Swelling properties of chitosan hydrogels

Abstract

Chitosan hydrogels were prepared by crosslinking chitosan with glutaraldehyde. The swelling behaviour of the crosslinked and uncross-linked hydrogels was measured by swelling the gels in media of different pH and at different temperatures. The swelling behavior was observed to be dependent on pH, temperature and the degree of crosslinking. The gel films were characterized by Fourier transform Infrared spectroscopy (FT-IR) and Differential Scanning Calorimetry (DSC). The glass transition temperature (Tg) and the amount of free water in the hydrogels decreased with increasing crosslinking in the hydrogels.

Injectable gel from squid pen chitosan for bone tissue engineering applications

“…RS and RC gels can uptake and hold water more than their own weights (values are[100 %). However, the maximum water uptake ratio of Bars with different letters are significantly different at p \ 0.05 \2000 w/w % was obtained in this study for RC gel samples, which is comparable and higher to the results reported by Rohindra et al [51] who observed 1200 % of water uptake result for the chitosan hydrogels, cross-linked with gluteraldehyde. The lower water uptake can be related to the type of chitosan, DDA, type of cross-linker and the molecular weight of the chitosan.…”

Physical and structural characterisation of zein and chitosan edible films using nanotechnology tools

“…Film thickness depends on each component's nature and composition [25]. The chitosan solution, as a consequence of its large swelling capacity [26], is denser than zein, which promotes the formation of a thicker film once the solution is dried in a constant volume container. The interactions among zein, chitosan and glycerol in the composite films could have resulted in reactions that promoted a change not only in the density of the materials but also in the structure that allowed more water to be retained.…”

Collagen-chitosan scaffold - Lauric acid plasticizer for skin tissue engineering on burn cases

“…The analysis indicates that the COOH functional group turned into a group -COOC- [12]. This is possible because in addition to chitosan experiencing cross belt with collagen, cross belt also occurs in groups C=O and NH2 groups [13]. Therefore, the scaffold can be degraded [14].…”