Sweat gland carcinoma: A clinico‐pathological reappraisal

Abstract

A case of sweat gland carcinoma arising from the right fifth finger which later metastasized to the regional lymph nodes and the lungs is the subject of this report which attempts to establish further the true characteristics of this definite pathological entity. The diagnosis of sweat gland carcinoma has been loosely applied to a variety of lesions, and it was not until recently that more exact and appropriate criteria were used to establish the diagnosis of sweat gland carcinoma. The case reported in this manuscript possesses most if not all the criteria necessary to make a diagnosis of sweat gland carcinoma. Further review of the literature shows that this is a rare and aggressive neoplasm as this case illustrates. Radical surgery of the primary lesions with radical regional lymph node dissection whenever possible is recommended for the initial treatment, and combination chemotherapy and radiotherapy may be employed in the palliative treatment of the more advanced forms of the disease.

Diagnostic dilemma in skin adnexa malignancy: a rare case report with review of literature

“…Apocrine adenocarcinoma also been observed to arise in association with other benign tumours such as apocrine adenoma and Apocrine hyperplasia. 6,7,8 It is often clinically diagnosed incorrectly. Mainly diagnosed on histopathological examination of resected specimen, which is again an incidental finding.…”

“…7,9,10 Treatment choice is wide local excision with adequate tumour free margins. 7,8 The prognosis of apocrine adenocarcinoma is very poor and its prognosis all depends on size of the tumors, histological type, lymph node involvement and distant metastasis. The disease-free survival rate for 10 years in the absence of metastasis to the lymph nodes is reported to be 56%.…”

Recurrent Pleural Effusion and Pulmonary Metastases from a Cutaneous Apocrine Tumour of the Axilla

“…Apocrine carcinomas manifest as non-tender single or multiple, firm, rubbery or cystic masses with red to purple overlying skin (1). The axilla is the most common site for apocrine gland carcinoma for its great abundance of these glands, followed by the anogenital region (2).…”

Applicability of lymphoscintigraphy with sentinel node biopsy to eccrine carcinoma of the head and neck

“…2,3 Traditionally, the recommended method of treatment has been wide excision of the primary tumor with possible regional lymph node dissection. [1][2][3][4][5][12][13][14][15] However, the role of lymph node dissection is only discussed in the literature with anecdotal outcomes. 3,12 For patients with clinically or radiographically involved regional lymph nodes, with an absence of known distant metas- tasis, nodal dissection with possible postoperative radiation has been used.…”