Highlights
Health systems in the least developed, fragile, and conflict-affected countries (LDFCAC) are chronically underfunded and are often sustained largely by international development assistance.
The perception of the impact of coronavirus disease 2019 (COVID-19) in LDFCAC populations is likely to be dwarfed by their experience with other existential threats, such as the daily need to find food for their families, violence, or even death from conflicts.
LDFCAC must have access to tests, treatments, and vaccines as they become available in developed countries.
As long as human mobility cannot be adequately curtailed, circulating severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in LDFCAC will become a permanent threat.
There is an urgent need in LDFCAC for funds to expand testing and contact-tracing, and when feasible, for the use of proximity-tracing technology and apps that allow people to self-report symptoms and confirmed infections.