Sustained silver-releasing dressing in the treatment of diabetic foot ulcers

Abstract

This study investigated the clinical performance and safety of a sustained silver-releasing foam dressing, Contreet Foam, in the treatment of diabetic foot ulcers. Twenty-seven patients with diabetic foot ulcers of grade I or II (Wagner's classification) were followed for six weeks: one week run-in using Biatain dressings, four weeks' treatment with Contreet dressings. Four ulcers healed during the four-week treatment with Contreet 56% in average. Contreet Foam showed good exudate management properties and was considered easy to use. Only two infections occurred showed that all six of the non-study ulcers developed an infection during the study. All ulcers (study ulcers as well as non-study ulcers) were treated according to good practice of diabetic wound care. There were no directions for the treatment of secondary wounds. No device-related adverse events were observed. This study demonstrated that Contreet Foam is safe and easy to use and effectively supports healing and good wound progress of diabetic foot ulcers.

Effectiveness of silver in wound care treatment

“…15 This study demonstrates the benefit of using a silver impregnated dressing in the treatment of chronic venous leg ulcers with signs of delayed healing. Similar to Rayman et al, 14 the authors of this study stated that the results of the study 'suggest an important role of sustained silver-releasing dressings in the treatment of critically colonized chronic wounds'. 15 Jurczak et al 16 compared Hydrofiber Ag to povidone-iodine gauze in the treatment of open surgical and traumatic wounds using the visual analogue scale (VAS) to assess pain and investigator evaluation of exudate handling, wound size and appearance, infection and ease of use for each treatment among other outcome measures.…”

“…(2) ionic silver; (3) infection; (4) Ag; (5) wound; (6) wound care; (7) ulcer; (8) diabetic foot ulcer; (9) pressure ulcer; (10) venous leg ulcer; (11) antimicrobial; (12) bacteria; (13) colonization; (14) alginate; (15) RCTs. Each of the keyword combinations listed above were separated by 'or' for each publication search.…”

“…Jørgensen et al 15 also examined the effectiveness of Contreet Foam dressing in wound care. However, unlike Rayman et al, 14 Jørgensen et al 15 compared Contreet Foam dressing to a foam dressing without added silver, Allevyn Hydrocellular, in the treatment of venous leg ulcers. Jørgensen et al 15 used Image Pro Plus S.O software with wound tracing sheets to assess wound healing and investigators evaluated ease of use, exudate level, leakage and odor.…”

A comparative study of the effect on healing of ulcer using silver dressing

“…8 Munter reported that silver dressing supports faster healing of delayed healing wounds. 3 No adverse reaction was observed in the study group where as in the control group 23.33 % (7) patients had adverse reactions which included itching and hyperpigmentation (Table 16).…”

Are Silver Products Safe and Effective for Chronic Wound Management?

“…Case series [13][14][15][16][17][18] and a retrospective chart review 19 (Table 3) on a total of 58 pressure ulcers, 213 venous ulcers, and 108 diabetic foot ulcers supported the general conclusion that silver dressings are safe on these chronic wounds. However, these data report ef- ionic released from the silver salt when it reacts with wound fluid.…”