Sustainable use of sodium butyrate as a source of bioactive additive: impact on calf growth performance, rumen fermentation characteristics, and microbial count

Rodríguez, Germán Buendía; Carmona, Diego; Elghandour, Mona M.Y.; Salem, Abdelfattah Z.M.; Soto, Héctor Reyes; Sánchez, Ricardo Ruiz; Adegbeye, Moyosore J.

doi:10.1007/s13399-022-02707-7

Cited by 4 publications

(2 citation statements)

References 22 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Contrary to what was expected, sodium butyrate supplementation did not exert a positive effect on the feed intake, weight gain, performance, and digestibility of the supplemented calves. These findings corroborate others that did not demonstrate increases in performance [36,37], DMI [19,37,38], or digestibility [34,36,39] through butyrate supplementation. Reinforcing our findings, previous works found no differences in ADG and biometrical evaluations such as WH, HG, and RH between supplemented and control animals when evaluating the same product and dosage used in this present work [35].…”

Section: Feed Intake Rumen Parameters Performance and Feed Efficiencysupporting

confidence: 90%

Effects of Supplementing Milk Replacer with Sodium Butyrate on Dairy Calves

Belli,

Coelho,

Campolina

et al. 2024

Animals

View full text Add to dashboard Cite

Diarrhea and respiratory diseases pose significant challenges in the rearing of pre-weaned calves, motivating the investigation of tools to improve gastrointestinal tract development, health, and overall performance in young calves. Consequently, the primary objective of this study was to assess the effectiveness of an additive incorporated into milk replacer to promote the development and health of the animals. Forty-six dairy calves were randomly assigned into two treatments: control (CON, n = 23; with 15 females and 8 males), and sodium butyrate (SB, n = 23; with 15 females and 8 males). The calves in the SB treatment group were supplemented with 4 g/d of unprotected sodium butyrate (Adimix, Adisseo, China), added to the milk replacer from 4 to 60 days of age. Water and starter were fed ad libitum. The study evaluated several parameters, including feed intake, nutrient digestibility, ruminal pH, ammonia and volatile fatty acids, blood metabolites (glucose, insulin-like growth factor type 1, urea, β–hydroxybutyrate), hemogram, health scores, performance, and feed efficiency. Bull calves were euthanized at 60 days of age for organ comparison, while heifer calves were assessed for carryover effects up to 90 days of age. Data were analyzed independently using linear mixed models using the nlme package in R, and the Artools package for non-parametric categorical outcomes. Although the feed intake and performance variables exhibited differences within weeks, no divergence was observed between treatment groups. Notably, a positive treatment-by-week interaction was identified for starter feed intake (p = 0.02) and total dry matter intake (p = 0.04) during pre-weaning for CON animals. Ruminal parameters, blood metabolites, and hemogram values such as glucose, urea, insulin-like growth factor type 1, mean corpuscular value, lymphocytes, and neutrophils displayed differences within weeks during the pre-weaning stage, but similar results within groups. No differences between supplemented and non-supplemented calves were found across nutrient digestibility, organ development, and histology. Regarding health scores, differences were noted within weeks for fecal and respiratory scores during the pre-weaning stage, and only the respiratory score during the post-weaning stage. Consequently, butyrate supplementation did not elicit improvements or negative effects in the body development or health status of dairy calves.

show abstract

Section: Feed Intake Rumen Parameters Performance and Feed Efficiencysupporting

confidence: 90%

Effects of Supplementing Milk Replacer with Sodium Butyrate on Dairy Calves

Belli,

Coelho,

Campolina

et al. 2024

Animals

View full text Add to dashboard Cite

show abstract

“…Similarly, although there was no significant effect of the addition of GAA on the efficiency of CH 4 , it was observed that efficiency increased quantitatively with all genotypes with GAA, since regardless of the state of the forage, the majority decreased CH 4 per unit from SCFA, ME, and OM. However, the state of the forage did affect the efficiency with the Olotillo and Amarillo genotypes; with Olotillo, this can be attributed to the low degradability caused by the high concentration of the detergent acid lignin, while with Amarillo, it was believed to be due to the increase in DMD, which increases gas production [83].…”

Section: Fermentation Characteristics and Ch 4 Conversion Efficiencymentioning

confidence: 96%

Effects of Guanidinoacetic Acid on Ruminal Fermentation and Greenhouse Gas Production Using Fresh Forage and Silage from Different Maize (Zea mays L.) Genotypes

et al. 2023

View full text Add to dashboard Cite

Guanidinoacetic acid (GAA) is a feed additive that promotes growth in animals, while maize (Zea mays L.) is used for the mitigation of ruminal greenhouse gases. However, it is unknown if GAA affects the efficiency of maize in mitigating gases or if there is synergy between them. Therefore, the objective of this study was to evaluate the in vitro production of total gas, methane (CH4), carbon monoxide (CO), and hydrogen sulfide (H2S), ruminal fermentation characteristics, and the CH4 conversion efficiency of fresh forage and silage of different genotypes (Amarillo, Montesa, Olotillo, Tampiqueño, and Tuxpeño) of maize, with and without the addition of GAA. The silage of the Amarillo genotype without AAG had the highest (p = 0.01) total gas production rate and the lowest (p = 0.044) delay time before gas production. In addition, at 48 h, the Amarillo silage with GAA increased the production of total gas (p = 0.0001) and CH4, as well as the proportion of CH4 (mL CH4 100 mL−1 total gas). The Amarillo and Tuxpeño genotype produced more (p = 0.033) CO in the first 24 h of incubation, while silage and the addition of GAA only increased (p = 0.001) CO at 6 h. The highest (p = 0.02) H2S production was observed with the ensiled Amarillo genotype with GAA. Regarding fermentation characteristics, the silage of the Amarillo and Montesa genotypes presented the highest degradation of dry matter (DMD), short-chain fatty acids (SCFA), and metabolizable energy (ME), and although there was no effect on CH4 efficiency, the Amarillo and Olotillo genotypes produced more SCFA, ME, and OM per unit of CH4. It can be concluded that rumen gas production, fermentation characteristics, and CH4 conversion efficiency are more influenced by the maize genotype and forage condition than by the addition of guanidinoacetic acid, and of the genotypes evaluated, the forage silage from Amarillo showed the best characteristics and efficiency of CH4.

show abstract