Susceptibility Vessel Sign on MRI Predicts Favorable Clinical Outcome in Patients with Anterior Circulation Acute Stroke Treated with Mechanical Thrombectomy

Abstract

BACKGROUND AND PURPOSE:The susceptibility vessel sign on MR imaging has been reported to indicate acute occlusion from erythrocyte-rich thrombus. The purpose of this study was to evaluate the influence of the susceptibility vessel sign seen on MR imaging before treatment on the clinical outcome after mechanical thrombectomy for anterior circulation acute stroke.

Susceptibility vessel sign on MRI predicts better clinical outcome in patients with anterior circulation acute stroke treated with stent retriever as first-line strategy

“…Our findings are in line with a previous smaller retrospective monocentric study, in which SVS+ appeared to be a radiologic biomarker predictive of favorable clinical outcome at 3 months after MT 10. However, a very large CI precluded any generalization of the results (OR=8.7; 95% CI 1.1 to 69.4; P value 0.…”

Prediction of Stroke Subtype and Recanalization Using Susceptibility Vessel Sign on Susceptibility-Weighted Magnetic Resonance Imaging

“…A recent study showed that the presence of an SVS predicted favorable clinical outcomes in patients with anterior circulation strokes who underwent endovascular treatment. 16 However, SVS was not significantly associated with successful recanalization (81% versus 70% of TICI ≥2b in the SVS-positive and SVS-negative groups, respectively; P =0.34). Soize et al showed that the longer thrombi were associated with poor recanalization using a stent retriever.…”

ASL and susceptibility-weighted imaging contribution to the management of acute ischaemic stroke

“…Whatever the origin of the thrombus, in acute ischaemic stroke, the susceptibility vessel sign would be correlated with:a lower rate of recanalisation after intravenous thrombolysis compared with arterial occlusion without the susceptibility vessel sign [10, 11], particularly for proximal localisations [12], for lengths greater than 20 mm, for thrombi with irregular contours [13], and for susceptibility artefacts extending beyond the arterial lumen [14];a favourable 3-month functional outcome in patients who undergo mechanical thrombectomy for anterior circulation occlusion [15], but not with a higher rate of recanalisation [16]. …”

“…a favourable 3-month functional outcome in patients who undergo mechanical thrombectomy for anterior circulation occlusion [15], but not with a higher rate of recanalisation [16]. …”