Susceptibility of Three Laboratory Strains of &lt;I&gt;Anopheles albimanus&lt;/I&gt; (Diptera: Culicidae) to Coindigenous &lt;I&gt;Plasmodium vivax&lt;/I&gt; Circumsporozoite Protein Phenotypes in Southern Mexico

González-Cerón, Lilia; Rodrı́guez, Mario H.; Santillán, Frida; Hernandez, Juan E.; Wirtz, Robert A.

doi:10.1603/0022-2585(2000)037[0331:sotlso]2.0.co;2

Cited by 6 publications

(2 citation statements)

References 21 publications

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“…The A/WS-R colony was developed in the late 1990s from mosquitoes gathered in the Soconusco region, the southern-most tip of Chiapas, Mexico. This strain is highly susceptible to P. vivax Vk210/Pvs25-A (refers to Pvs25-130Ile) [12, 19] and almost refractory to either P. vivax Vk247 or Vk210 and Pvs25-B (refers to Pvs25-130Thr) [12]. The P/TAP-R colony, raised in 1995 from larvae collected in Malpaso (Tapachula, Chiapas) [17], was very susceptible to P. vivax Vk247 and Vk210 expressing Pvs25-B but almost resistant to Vk210/Pvs25-A [12].…”

Section: Methodsmentioning

confidence: 99%

Plasmodium vivax CSP-Pvs25 variants from southern Mexico produce distinct patterns of infectivity for Anopheles albimanus versus An. pseudopunctipennis, in each case independent of geographical origin

et al. 2019

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Background The susceptibility of Anopheles albimanus and An. pseudopunctipennis to local Plasmodium vivax has been associated in southern Mexico with two ookinete surface proteins (Pvs25/28) polymorphism. Perhaps parasite population selection (i.e. adaptation to local vectors) contributes to this phenomenon. It is also possible that certain molecular interactions exist between P. vivax and each mosquito species independently of geographical origin. This study aimed to explore the susceptibility of An. albimanus and An. pseudopunctipennis (collected from different geographical sites) to P. vivax cspVk/Pvs25-130 haplotypes from southern Mexico. Results Of the 120 P. vivax -infected blood samples used to simultaneously feed An. albimanus and An. pseudopunctipennis mosquitoes originating from various geographical sites, 80 produced at least one infected mosquito species. Three parasite haplotypes were identified in infected blood: Vk210/Pvs25-A (12.5%), Vk210/Pvs25-B (20%) and Vk247/Pvs25-B (67.5%). Two parameters (the proportion of infected mosquitoes and number of oocysts/mosquito) showed a similar pattern for each mosquito species (independently of geographical origin). For An. albimanus mosquitoes (from the Pacific coast, Mexican gulf and Lacandon Forest lowlands), these two parameters were higher in specimens infected with P. vivax Vk210/Pvs25-A versus Vk210/Pvs25-B or Vk247/Pvs25-B ( P < 0.001). For An. pseudopunctipennis mosquitoes (from the Pacific coast, northeast Mexico and east Guatemala foothills), the same two parameters were higher in specimens infected with Vk247/Pvs25-B or Vk210/Pvs25-B versus Vk210/Pvs25-A ( P < 0.001). Higher infection rates were caused by Vk247/Pvs25-B than Vk210/Pvs25-B parasites in An. pseudopunctipennis ( P = 0.011 ) and An. albimanus ( P = 0.001). The greatest parasitaemia, gametocytaemia and microgamete formation was observed in Vk247/Pvs25-B infected blood, and each of these parameters correlated with each other and with the number of oocysts in An. pseudopunctipennis from the sympatric colony. Conclusions Plasmodium vivax Vk247/Pvs25-B infections were the most prevalent, likely due to the higher parasitaemia produced in the susceptible vector (especially An. pseudopunctipennis ). The analysis of mosquito-parasite interactions indicate that ...

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Section: Methodsmentioning

confidence: 99%

Plasmodium vivax CSP-Pvs25 variants from southern Mexico produce distinct patterns of infectivity for Anopheles albimanus versus An. pseudopunctipennis, in each case independent of geographical origin

et al. 2019

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“…albimanus was the predominant species [7]. This species is geographically variable in its infectivity by Plasmodium species throughout its distribution in the Americas [10-13]. …”

Section: Introductionmentioning

confidence: 99%

Population structure analyses and demographic history of the malaria vector Anopheles albimanus from the Caribbean and the Pacific regions of Colombia

Gutiérrez

Naranjo-Díaz

Cienfuegos-Gallet

et al. 2009

Malar J

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BackgroundAnopheles albimanus is an important malaria vector in some areas throughout its distribution in the Caribbean and the Pacific regions of Colombia, covering three biogeographic zones of the neotropical region, Maracaibo, Magdalena and Chocó.MethodsThis study was conducted to estimate intra-population genetic diversity, genetic differentiation and demographic history of An. albimanus populations because knowledge of vector population structure is a useful tool to guide malaria control programmes. Analyses were based on mtDNA COI gene sequences and four microsatellite loci of individuals collected in eight populations from the Caribbean and the Pacific regions of Colombia.ResultsTwo distinctive groups were consistently detected corresponding to COI haplotypes from each region. A star-shaped statistical parsimony network, significant and unimodal mismatch distribution, and significant negative neutrality tests together suggest a past demographic expansion or a selective sweep in An. albimanus from the Caribbean coast approximately 21,994 years ago during the late Pleistocene. Overall moderate to low genetic differentiation was observed between populations within each region. However, a significant level of differentiation among the populations closer to Buenaventura in the Pacific region was observed. The isolation by distance model best explained genetic differentiation among the Caribbean region localities: Los Achiotes, Santa Rosa de Lima and Moñitos, but it could not explain the genetic differentiation observed between Turbo (Magdalena providence), and the Pacific region localities (Nuquí, Buenaventura, Tumaco). The patterns of differentiation in the populations from the different biogeographic provinces could not be entirely attributed to isolation by distance.ConclusionThe data provide evidence for limited past gene flow between the Caribbean and the Pacific regions, as estimated by mtDNA sequences and current gene flow patterns among An. albimanus populations as measured by MS loci which may be mainly influenced by semi-permeable natural barriers in each biogeographical region that lead to the genetic differences and effective population sizes detected. The relatively high genetic differentiation in the port city of Buenaventura may be the result of specific ecological conditions, human migration and activities and/or differences in effective population sizes. This knowledge could serve to evaluate and coordinate vector control strategies in these regions of Colombia.

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Ookinete destruction within the mosquito midgut lumen explains Anopheles albimanus refractoriness to Plasmodium falciparum (3D7A) oocyst infection

Baton

Ranford-Cartwright

2012

International Journal for Parasitology

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Graphical abstractHighlights► Development of a human malaria parasite is compared between two mosquito vector species. ► Ookinete formation within the midgut lumen is equivalent in both mosquito species. ► Plasmodium falciparum fails to produce oocyst infections in Anopheles albimanus. ► All ookinetes are destroyed within the midgut lumen of A. albimanus. ► Malaria parasite survival in all of the different midgut compartments is quantified.

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Susceptibility of Three Laboratory Strains of <I>Anopheles albimanus</I> (Diptera: Culicidae) to Coindigenous <I>Plasmodium vivax</I> Circumsporozoite Protein Phenotypes in Southern Mexico

Cited by 6 publications

References 21 publications

Plasmodium vivax CSP-Pvs25 variants from southern Mexico produce distinct patterns of infectivity for Anopheles albimanus versus An. pseudopunctipennis, in each case independent of geographical origin

Plasmodium vivax CSP-Pvs25 variants from southern Mexico produce distinct patterns of infectivity for Anopheles albimanus versus An. pseudopunctipennis, in each case independent of geographical origin

Population structure analyses and demographic history of the malaria vector Anopheles albimanus from the Caribbean and the Pacific regions of Colombia

Ookinete destruction within the mosquito midgut lumen explains Anopheles albimanus refractoriness to Plasmodium falciparum (3D7A) oocyst infection

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