Survival of AIDS patients in a city in southeastern Brazil

Menesia, Elisa Ortúzar; Passos, A.D.C; Monteiro, Maria Elizabeth Brêa; Dal-Fabbro, Amaury Lélis; Laprega, Milton Roberto

doi:10.1590/s1020-49892001000700005

Cited by 5 publications

(2 citation statements)

References 14 publications

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“…This creates an important problem for survival analyses, in that the inclusion of these patients produces a bias by systematically reducing the survival period observed. Nevertheless, we have followed the procedures used in many other studies by including these cases, even though this results in shorter observed survival times 42 .…”

Section: Discussionmentioning

confidence: 99%

AIDS by mother-to-child transmission: survival analysis of cases followed from 1983 to 2002 in different regions of Brazil

Matida

Ramos

Moncau³

et al. 2007

Cad. Saúde Pública

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Antiretroviral therapy contributes to decreasing morbidity and mortality, and ultimately to increasing survival. In Brazil, there are regional differences in HIV epidemiology regarding pregnant women and children with HIV/AIDS. This study evaluates survival time after AIDS diagnosis in 914 children infected by mother-to-child transmission, reported between 1983 and 1998 and followed until 2002, in Brazil's five regions. Time between birth and HIV diagnosis decreased over the years, mainly in the South and Southeast Regions. There was a significant improvement in survival; more than 75% of cases were still living four years after diagnosis in the 1997-1998 group. This Brazilian study demonstrates that even with regional inequalities in health care infrastructure it is possible for a developing country to establish an effective system of universal and free access to antiretroviral therapy that produces a significant increase in survival for children with AIDS.

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Section: Discussionmentioning

confidence: 99%

AIDS by mother-to-child transmission: survival analysis of cases followed from 1983 to 2002 in different regions of Brazil

Matida

Ramos

Moncau³

et al. 2007

Cad. Saúde Pública

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show abstract

“…Another study, carried out in Ribeirão Preto, São Paulo State 16 , documented a substantial, but less pronounced increase, of the median survival time, vis-à-vis the national study 12 , and the studies carried out in Rio de Janeiro 13,15 . Data abstracted from the city database pointed to a median survival of approximately 29 months for those patients diagnosed with AIDS in 1996-1997.…”

Section: Post-haart Survival In Different Regional Contextsmentioning

confidence: 97%

The first ten years: achievements and challenges of the Brazilian program of universal access to HIV/AIDS comprehensive management and care, 1996-2006

et al. 2007

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The impact of late diagnosis on the survival of patients following their first AIDS-related hospitalization in Belo Horizonte, Brazil

2011

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The purpose of this study is to estimate the survival probability of patients following their first admission for the treatment of AIDS to an infectious disease reference hospital in Belo Horizonte, Brazil, during 2005. Study subjects were monitored during a 12-month period to identify factors associated with survival probability. Late diagnosis was recorded among many of the 250 study subjects: almost half (44.8%) were diagnosed less than 30 days prior to or during their hospitalization. A high mortality rate was also detected: 39.6% of the subjects died during the 12 months of monitoring. The cumulative survival probability of the cohort group was estimated at 68.0% after 3 months and at 61.2% after 12 months. However, certain patient subgroups analyzed had even lower cumulative survival probabilities after 12 months of monitoring: if diagnosed during hospitalization, it was estimated at only 48.0% and those with no record of antiretroviral treatment had a 48.5% cumulative survival probability. Patients with severe anemia had the lowest survival probability, similar among the two lymphocyte count groups (<1000 mm(3) and ≥1000 mm(3)), the former with a 45.5% survival probability and the latter with a 46.7% one. The proportional death risk was 2.5-fold higher for men residing in other area than the capital city of the State of Minas Gerais and greater metropolitan region when compared with women residing there. The findings of this study highlight the importance of early diagnosis for predicting patient survival and reinforce the necessity of facilitating HIV diagnosis.

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Survival of AIDS patients in a city in southeastern Brazil

Cited by 5 publications

References 14 publications

AIDS by mother-to-child transmission: survival analysis of cases followed from 1983 to 2002 in different regions of Brazil

AIDS by mother-to-child transmission: survival analysis of cases followed from 1983 to 2002 in different regions of Brazil

The first ten years: achievements and challenges of the Brazilian program of universal access to HIV/AIDS comprehensive management and care, 1996-2006

The impact of late diagnosis on the survival of patients following their first AIDS-related hospitalization in Belo Horizonte, Brazil

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