Survival for eight major cancers and all cancers combined for European adults diagnosed in 1995–99: results of the EUROCARE-4 study

Berrino, Franco; Angelis, Roberta De; Sant, Milena; Rosso, Stefano; Lasota, Magdalena B; Coebergh, Jan Willem; Santaquilani, Mariano

doi:10.1016/s1470-2045(07)70245-0

Cited by 717 publications

(506 citation statements)

References 18 publications

(20 reference statements)

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“…1 Mean (SD). 2 Self-reported data. Number of participants with missing data: For total flavonoids T1:6.6%; T2: 3.5%; T3: 14.6%; for TRAP T1: 5.7%; T2: 9.6%; T3: 9.4%.…”

Section: Discussionmentioning

confidence: 99%

Dietary flavonoid, lignan and antioxidant capacity and risk of hepatocellular carcinoma in the European prospective investigation into cancer and nutrition study

Zamora-Ros

Fedirko

Trichopoulou

et al. 2013

Intl Journal of Cancer

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Limited epidemiological evidence suggests a protective role for plant foods rich in flavonoids and antioxidants in hepatocellu- lar cancer (HCC) etiology. Our aim was to prospectively investigate the association between dietary intake of flavonoids, lignans and nonenzymatic antioxidant capacity (NEAC) and HCC risk. Data from the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort including 477,206 subjects (29.8% male) recruited from ten Western European countries, was analyzed. Flavonoid, lignan and NEAC intakes were calculated using a compilation of existing food composition databases linked to dietary information from validated dietary questionnaires. Dietary NEAC was based on ferric reducing antioxidant capacity (FRAP) and total radical-trapping antioxidant parameter (TRAP). Hepatitis B/C status was measured in a nested case– control subset. During a mean follow-up of 11-years, 191 incident HCC cases (66.5% men) were identified. Using Cox regres- sion, multivariable adjusted models showed a borderline nonsignificant association of HCC with total flavonoid intake (highest versus lowest tertile, HR 5 0.65, 95% CI: 0.40–1.04; ptrend 5 0.065), but not with lignans. Among flavonoid subclasses, flava- nols were inversely associated with HCC risk (HR 5 0.62, 95% CI: 0.39–0.99; ptrend 5 0.06). Dietary NEAC was inversely associ- ated with HCC (FRAP: HR 0.50, 95% CI: 0.31–0.81; ptrend 5 0.001; TRAP: HR 0.49, 95% CI: 0.31–0.79; ptrend 5 0.002), but statistical significance was lost after exclusion of the first 2 years of follow-up. This study suggests that higher intake of die- tary flavanols and antioxidants may be associated with a reduced HCC risk

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“…1 Mean (SD). 2 Self-reported data. Number of participants with missing data: For total flavonoids T1:6.6%; T2: 3.5%; T3: 14.6%; for TRAP T1: 5.7%; T2: 9.6%; T3: 9.4%.…”

Section: Discussionmentioning

confidence: 99%

Dietary flavonoid, lignan and antioxidant capacity and risk of hepatocellular carcinoma in the European prospective investigation into cancer and nutrition study

Zamora-Ros

Fedirko

Trichopoulou

et al. 2013

Intl Journal of Cancer

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“…In Europe 46% of all those diagnosed with cancer will be living 10 or more years beyond initial treatment (1). By 2030 it is projected that there will be more than 4 million cancer survivors within the UK population (2) and 13.7 million in the USA (3).…”

Section: Introductionmentioning

confidence: 99%

Patient-reported Outcome Measures in Radiotherapy: Clinical Advances and Research Opportunities in Measurement for Survivorship

2015

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“…In presence of an increase of breast cancer survivors [17], of an increased CBC risk among breast cancer patients [18] and of a worldwide obesity epidemic [19], we investigated a potential association between BMI and CBC events. Evolution of CBC hazard during the follow-up was assessed.…”

Section: Time-dependent Association a Introductionmentioning

confidence: 99%

Increased risk of contralateral breast cancers among overweight and obese women: a time-dependent association

Majed

Dozol

Ribassin-Majed

et al. 2010

Breast Cancer Res Treat

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Survival for eight major cancers and all cancers combined for European adults diagnosed in 1995–99: results of the EUROCARE-4 study

Cited by 717 publications

References 18 publications

Dietary flavonoid, lignan and antioxidant capacity and risk of hepatocellular carcinoma in the European prospective investigation into cancer and nutrition study

Dietary flavonoid, lignan and antioxidant capacity and risk of hepatocellular carcinoma in the European prospective investigation into cancer and nutrition study

Patient-reported Outcome Measures in Radiotherapy: Clinical Advances and Research Opportunities in Measurement for Survivorship

Increased risk of contralateral breast cancers among overweight and obese women: a time-dependent association

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