Survival and predictive factors of mortality after 30 days in patients treated with percutaneous implantation of the CoreValve aortic prosthesis

Muñoz-García, Antonio J.; Hernández-García, José M.; Jiménez-Navarro, Manuel F.; Alonso‐Briales, Juan H.; Domínguez-Franco, Antonio J.; Rodríguez–Bailón, Isabel; Molina-Mora, María J.; Hernández-Rodríguez, Paula; Such-Martínez, Miguel; Teresa–Galván, Eduardo de

doi:10.1016/j.ahj.2011.11.013

Cited by 22 publications

(16 citation statements)

References 27 publications

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“…Our rate of bleeding and vascular complications is comparable with recent meta-analysis (6.6%) [12] and real-world TAVI registries (2.2 -16%) [5,13,14]. The crossover percentage from radial to femoral was low (<3%), which is comparable to previous studies and acceptable bearing in mind the age of our patient population, expected vessel calibre and subclavian tortuosity.…”

Section: Discussionsupporting

confidence: 92%

Transradial Secondary Arterial Access for Transcatheter Aortic Valve Implantation: Experience and Limitations

Wynne¹,

Rampat²,

Trivedi³

et al. 2015

Heart, Lung and Circulation

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Section: Discussionsupporting

confidence: 92%

Transradial Secondary Arterial Access for Transcatheter Aortic Valve Implantation: Experience and Limitations

Wynne¹,

Rampat²,

Trivedi³

et al. 2015

Heart, Lung and Circulation

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“…ADL dependence (5 minutes) was statistically significantly associated with mortality in 2 of the 3 studies. (54, 55) The Clinical Frailty Scale (3 minutes), a global assessment based on medical problems, activity level, and disability, predicted mortality,(50, 60) whereas subjective assessment without such a scale did not. (12, 56, 57) A majority of studies of single-component instruments were conducted in highly representative samples, but the risk of bias was high due to determination of frailty status without using previously validated or clinical cutpoints and lack of validation (Appendix Figure 2 panel A).…”

Section: Resultsmentioning

confidence: 99%

“…Although widely validated frailty phenotype(17) predicted mortality and MACCE after TAVR,(59) this finding was not consistent in other studies. (49, 54) The deficit accumulation frailty index is another validated frailty instrument,(18, 67) but its association with clinical outcomes has not been tested in patients undergoing cardiac surgical procedures.…”

Section: Discussionmentioning

confidence: 99%

Preoperative Frailty Assessment and Outcomes at 6 Months or Later in Older Adults Undergoing Cardiac Surgical Procedures

et al. 2016

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Background Frailty assessment may inform surgical risk and prognosis that are not captured by conventional surgical risk scores. Purpose To evaluate the evidence for various frailty instruments to predict mortality, functional status, or major adverse cardiovascular and cerebrovascular events (MACCE) in older adults undergoing cardiac surgical procedures. Data Sources MEDLINE and EMBASE (without language restrictions), from their inception to May 2, 2016. Study Selection Cohort studies that evaluated the association of frailty with mortality or functional status at ≥6 months in patients aged ≥60 years undergoing major or minimally invasive cardiac surgical procedures. Data Extraction Two reviewers independently extracted study data and assessed study quality. Data Synthesis Mobility, disability, and nutrition were frequently assessed domains of frailty in both types of procedures. In patients undergoing major procedures (N=18388, 8 studies), 9 frailty instruments were evaluated. There was moderate-quality evidence to assess mobility or disability and very-low-to-low-quality evidence to use a multi-component instrument to predict mortality or MACCE. No studies examined functional status. In patients undergoing minimally invasive procedures (N=5177, 17 studies), 13 frailty instruments were evaluated. There was moderate-to-high-quality evidence to assess mobility to predict mortality or functional status. Several multi-component instruments predicted mortality, functional status, or MACCE, but the quality of evidence was low to moderate. Multi-component instruments that measure different frailty domains seemed to outperform single-component instruments. Limitations Heterogeneity of frailty assessment, limited generalizability of multi-component frailty instruments, few validated frailty instruments, and potential publication bias. Conclusions Frailty status, assessed by mobility, disability, and nutritional status, can predict mortality at 6 months or later after major cardiac surgical procedures and functional decline after minimally invasive cardiac surgical procedures. Primary Funding Source National Institute on Aging and National Heart, Lung, and Blood Institute; there was no registration for this review.

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“…[5][6][7][8][12][13][14][15][16][18][19][20]24,25,30,33 One-year mortality of men and women was 22.0% and 16.9%, respectively. Pooled analysis using a random-effects model showed that men had significantly higher 1-year mortality (pooled RR, 1.30; 95% CI, 1.14-1.49; Figure 7).…”

Section: One-year Mortalitymentioning

confidence: 99%

Sex-Related Differences in Outcomes After Transcatheter Aortic Valve Implantation

Zhang

Liao

Peng

et al. 2013

Circ: Cardiovascular Interventions

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Studies were initially screened at the level of title and abstract, and then full-length reports were retrieved for detailed evaluation. Two authors independently selected articles according to prespecified inclusion and exclusion criteria. Articles were included if they (1) reported Background-There were considerable discrepancies with regard to sex-related differences in complications and prognosis after transcatheter aortic valve implantation. Methods and Results-The Cochrane library and PubMed online databases were searched. Articles reporting sex-specific post-transcatheter aortic valve implantation complications and mortality were identified. Two authors selected studies and extracted data independently. Random-and fixed-effects models were used depending on between-study heterogeneity. There were 27 articles, a total of 9118 patients, enrolled in our systematic review and meta-analysis, including 4176 men and 4942 women. Pooled analyses suggested considerable sex-related differences in complications and early as well as midterm outcomes after transcatheter aortic valve implantation. The difference in the risk for heart block requiring permanent pacemaker implantation was noted to be significant only in the subgroup of the CoreValve-dominating studies (pooled risk ratio [RR, men versus women], 1.29; 95% confidence interval [CI], 1.13-1.47). Although men had significantly lower risks for major/life-threatening bleeding (pooled RR, 0.81; 95% CI, 0.68-0.96) and major vascular complications (pooled RR, 0.49; 95% CI, 0.37-0.66), they had poorer prognosis. In fact, male sex was associated with significantly higher risks for deaths at both 30 days (RR, 1.37; 95% CI, 1.07-1.76) and 1 year (RR, 1.30; 95% CI, 1.14-1.49). Conclusions-Although men had lower risks for major/life-threatening bleeding and major vascular complications after transcatheter aortic valve implantation, they had less favorable short-term and midterm survival. (Circ Cardiovasc Interv. 2013;6:543-551.)

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Survival and predictive factors of mortality after 30 days in patients treated with percutaneous implantation of the CoreValve aortic prosthesis

Cited by 22 publications

References 27 publications

Transradial Secondary Arterial Access for Transcatheter Aortic Valve Implantation: Experience and Limitations

Transradial Secondary Arterial Access for Transcatheter Aortic Valve Implantation: Experience and Limitations

Preoperative Frailty Assessment and Outcomes at 6 Months or Later in Older Adults Undergoing Cardiac Surgical Procedures

Sex-Related Differences in Outcomes After Transcatheter Aortic Valve Implantation

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