The problem of managing medical hazardous and toxic waste still becomes an obstacle faced by most hospitals, due to the limited facilities, infrastructure, manpower, and of course the very large funds required. X Hospital Palembang has implemented a liquid medical hazardous and toxic materials waste management system at the Wastewater Treatment Plant (WWTP) using the aerobic filter method. This research aimed to evaluate the liquid medical hazardous and toxic waste management system carried out at X Hospital Palembang and whether it follows the Indonesian Minister of Health Regulation Number 7 of 2019 concerning Hospital Environmental Health. It also hoped that it can help provide assessments for the accreditation programs. This research was conducted using interviews, field observations, and laboratory tests such as bioassay (BOD) to measure the effects of a substance on a living organism, the chemical oxygen demand (COD) to measure the number of organic pollutants in a water body as an indicator of water quality, total dissolved solids (TDS) to find out the measurement of the total amount of dissolved organic and inorganic content present in water, the total suspended solids (TSS) to determine the operational behavior of a waste treatment system, oil and fat test to identify the presence of oils and fats in the given sample, a methylene blue active substances assay (MBAS) to detect the presence of anionic, ammoniacal nitrogen (NH3-N) to find out the amount of ammonia in waste products, and literature studies. Based on the research results, almost all processes in the liquid medical hazardous and toxic waste management system are in accordance with regulations. However, it needs to be corrected that the liquid waste quality test needs to be done at the beginning of the month; then analysis and follow-up are carried out if there are quality standards that do not fill the requirements. DO check has not been done for daily self-monitoring of liquid waste quality. Health checks, routine vaccinations, and special training for waste management officers have not been done.