Surgical treatment of obesity

Albaugh, Vance L.; Abumrad, Naji N.

doi:10.12688/f1000research.13515.1

Cited by 33 publications

(26 citation statements)

References 113 publications

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“…Another study has found that RYGB and SG have similar effects in improving body weight [23]. Our results also showed that although the BW of the patients improved significantly 12 months after the operation, there was no significant difference between the two groups.…”

Section: Discussionsupporting

confidence: 68%

The Correlation Between RDW, MPV and Weight Indices After Metabolic Surgery in Patients with Obesity and DM/IGR: Follow-Up Observation at 12 Months

et al. 2020

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Introduction Red blood cell distribution width (RDW) and mean platelet volume (MPV) are both new biomarkers for the prognosis of many diseases. This study aimed to observe the predictive values of RDW and MPV for weight loss after different metabolic surgeries in patients with obesity and abnormal glucose metabolism [diabetes mellitus or impaired glucose regulation (DM/IGR)]. Methods We retrospectively analyzed the body weight (BW), body mass index (BMI) and blood routine index of 98 patients with obesity and DM/IGR who underwent Roux-en-Y gastric bypass (RYGB) or sleeve gastrectomy (SG). Results Levels of RDW and MPV in both groups were significantly higher than before 1 month after surgery and then gradually decreased. Twelve months after surgery, the RDW level in the RYGB group was significantly lower than that before surgery. In the RYGB group, the RDW level of patients in the high-level percentage weight loss (%BW) (≥ 31.90) at 6 and 12 months after surgery decreased significantly compared to those in the corresponding low level. %BW and change in BW and BMI (ΔBW and ΔBMI) at 6 and 12 months after surgery in the high-level RDW (≥ 12.90) before surgery were significantly higher than those in the low level in the RYGB group. No significant difference in weight index was found in the high and low levels of the MPV before surgery in either group at other follow-up time points. Conclusions Preoperative baseline RDW and postoperative RDW levels can preliminarily predict the effect of different metabolic surgeries in patients with obesity and DM/IGR.

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Section: Discussionsupporting

confidence: 68%

The Correlation Between RDW, MPV and Weight Indices After Metabolic Surgery in Patients with Obesity and DM/IGR: Follow-Up Observation at 12 Months

et al. 2020

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“…Negative health consequences of obesity include cardiovascular disease, obstructive sleep apnea (OSA), systemic hypertension, pulmonary hypertension, diabetes, musculoskeletal problems, and various malignancies [1]. Given the severe health consequences of obesity and the difficulty that many patients have maintaining a healthy weight, surgical management has become an effective therapeutic option for many patients with morbid obesity [2].…”

Section: Introductionmentioning

confidence: 99%

Low-Dose Ketamine Infusion for Perioperative Pain Management in Patients Undergoing Laparoscopic Gastric Bypass: A Prospective Randomized Controlled Trial

Seman

Malan

Buras

et al. 2021

Anesthesiology Research and Practice

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Introduction. Obesity is a common comorbidity seen in the perioperative setting and is associated with many diseases including cardiovascular disease and obstructive sleep apnea. Laparoscopic Roux-en-Y gastric bypass is the gold standard surgical treatment for patients whose weight is refractory to diet and exercise. Caring for these patients perioperatively presents unique challenges to anesthesiologists and is associated with an increased risk of adverse respiratory events. In our study, we hypothesize that a low-dose perioperative ketamine infusion will reduce opioid consumption and improve analgesia when compared to standard therapy. Methods. This is a single-center, prospective randomized controlled study enrolling 35 patients in total. Patients were randomized equally into the ketamine and control group. Preop, intraop, and postop management regimens were standardized. The ketamine group received a 0.3 mg/kg ideal body weight ketamine bolus after induction followed by a 0.2 mg/kg/hr ketamine infusion continued into the postop setting for up to 24 hours. Data collected included total perioperative opioids used converted to oral morphine equivalents (ME), pain scores, side effects, hospital length of stay, and patient satisfaction captured via postoperative questionnaires. Results. The use of perioperative opioid consumption was significantly lower in the ketamine group when compared with the control group (179.9 ME versus 248.7 ME, P = 0.03 ). There was no statistically significant difference in pain scores or hospital length of stay postoperatively between the two groups. There were also no reported adverse respiratory events, prolonged sedation, agitation, or other side effects reported in either group. The patient satisfaction questionnaires showed a significant difference with the ketamine group reporting lower maximum pain scores, a decrease in how pain limited activities of daily living once discharged, and increased hospital pain management satisfaction scores. Conclusions. Perioperative low-dose ketamine infusions significantly reduced opioid consumption in morbidly obese patients undergoing laparoscopic gastric bypass surgery.

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“…Excess weight is thought to be responsible for one out of every 13 deaths in the EU. 3 The consequential economic inferences and the load on national health expenses are quite significant.…”

Section: Introductionmentioning

confidence: 99%

Updated modalities for management of obesity

Alsudairy

Alsadhan²,

Alghaith

et al. 2021

Int J Community Med Public Health

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Obesity treatment has become vastly more challenging as our comprehension of weight control has grown. Its treatment needs a close collaboration between a dedicated multidisciplinary healthcare team and a motivated patient. The team can include dietitian, health educator, physical activity mentor, personal trainer, clinical psychologist, and physician will be among the team members. Successful obesity care should overcome both the medical and social burdens of the condition. New prevention methods have Aby health care professionals since it is a condition with significant health implications. Obesity management consists of many options surgically, pharmacologically, dietary and physical activity. The best management option for each patient is determined by a healthcare professional. Bariatric surgery results in a larger decrease in BMI in the short and long term, when compared to non-surgical interventions. However, doctors and patients should recommend bariatric surgery at a lower threshold where lifestyle and pharmacological treatments have failed. Updates in obesity management are regular, and healthcare workers should continuously be updated with these management modalities.

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Surgical treatment of obesity

Cited by 33 publications

References 113 publications

The Correlation Between RDW, MPV and Weight Indices After Metabolic Surgery in Patients with Obesity and DM/IGR: Follow-Up Observation at 12 Months

The Correlation Between RDW, MPV and Weight Indices After Metabolic Surgery in Patients with Obesity and DM/IGR: Follow-Up Observation at 12 Months

Low-Dose Ketamine Infusion for Perioperative Pain Management in Patients Undergoing Laparoscopic Gastric Bypass: A Prospective Randomized Controlled Trial

Updated modalities for management of obesity

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