Surgical treatment of low anterior resection syndrome

Расулов, А. О.; Байчоров, А. Б.; Merzlykova, A M; Овчинникова, А. И.; Semyanikhina, A. V.

doi:10.17116/hirurgia202011153

Cited by 4 publications

(6 citation statements)

References 27 publications

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“…If these treatments were not working wonderfully, it's recommended to perform stoma surgery. the de nitive stoma surgery was considered if major LARS persisted for more than 2 years [7,21,28]. In 2021, K. Neumann et.al., [50] found that transanal endoscopic microsurgery (TEM) for rectal tumors was associated with signi cantly reduced hospitalization costs, which far exceeded the cost of acquiring and maintaining the technology, and reduced the incidence of LARS, so recommended that if possible use TEM to treat rectal cancer.…”

Section: Discussionmentioning

confidence: 99%

“…Every item has three options with a de ned scoring system used for evaluating the severity. The patients were divided into the no (0-20), minor (21)(22)(23)(24)(25)(26)(27)(28)(29), and major (30-42) LARS groups depending on their total score (Table 2). We used the Chinese version of the questionnaire.…”

Section: Lars Questionnaire and Data Collectionmentioning

confidence: 99%

“…LARS generally consists of fecal incontinence, urgency, and incomplete evacuation or evacuation di culties. several articles reported the leakage of gas and stool, stool clustering, frequent bowel movements, evacuation, and urgency as the main complaints [1,7,16,[19][20][21]. LARS can have two types of symptoms, the rst type appears within 6-12 months after surgery, which is called short-term symptoms.…”

Section: Introductionmentioning

confidence: 99%

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The Risk Factors of Low Anterior Resection Syndrome After Colorectal Cancer Surgery Compared with the Last Decade Studies

Kim

et al. 2022

Preprint

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Purpose This study aims to identify the independent risk factors compared with the last decade studies in the low anterior resection syndrome (LARS) after surgery for colorectal cancer (CRC). Method This was a cross-sectional, single-institution study in the Second Affiliation Hospital of Dalian Medical University, China. Patients underwent sphincter-preserving low anterior resection with total or partial mesorectal resection (with or without protective ileostomy) and completed a self-filled questionnaire over the phone to assess postoperative bowel dysfunction from January 2017 to December 2019. The predictors of LAR were evaluated using univariate and multivariate analyses, and compared with the last decade studies. Result The study population was 566 patients, 264 (46.64%), 224 (39.58%), and 78 (13.78%) patients with no, minor, and major LARS, respectively. In the univariate analysis, independent factors such as tumor location and size, anastomotic height, protective ileostomy, post-operation chemoradiotherapy, tumor T stage, lymphatic nodal metastasis classification, surgery duration, and time interval for closure of stoma were significantly associated with LARS points while we found the tumor T stage and lymphatic nodal metastasis classification as the new independent risk factors compared with the last decade studies. in the multivariate analysis, factors such as low and middle tumor location and protective ileostomy, and post operation treatment, nodal metastasis classification were the independent risk factors for major LARS. Conclusion The new independence risk factors were tumor T stage and lymphatic nodal metastasis status in univariate analysis in our study, with anastomotic height, low and middle tumor location, protective ileostomy, post-operation chemoradiotherapy, nodal metastasis status increasing LARS point in multivariate analysis after surgery for CRC.

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Section: Discussionmentioning

confidence: 99%

Section: Lars Questionnaire and Data Collectionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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The Risk Factors of Low Anterior Resection Syndrome After Colorectal Cancer Surgery Compared with the Last Decade Studies

Kim

et al. 2022

Preprint

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show abstract

“…LARS generally consists of fecal incontinence, urgency, and incomplete evacuation or evacuation difficulties. Several articles reported the leakage of gas and stool, stool clustering, frequent bowel movements, evacuation, and urgency as the main complaints ( 1 , 7 , 14 , 17 , 28 , 29 ). LARS can have two types of symptoms, the first type appears within 6–12 months after surgery, which is called short-term symptoms.…”

Section: Discussionmentioning

confidence: 99%

“…Every item has three options with a defined scoring system used for evaluating the severity. The patients were divided into the no (0–20), minor ( 21 – 29 ), and major ( 30 – 42 ) LARS groups depending on their total score ( Table 2 ).…”

Section: Methodsmentioning

confidence: 99%

The risk factors of low anterior resection syndrome after colorectal cancer surgery: A retrospective study of 566 patients in a single institution in China

Kang

et al. 2022

Front. Surg.

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PurposeThis study aims to identify the independent risk factors in the low anterior resection syndrome (LARS) after surgery for colorectal cancer (CRC).MethodThis was a retrospective, single-institution study in the Second Affiliation Hospital of Dalian Medical University, China. Patients underwent sphincter-preserving low anterior resection with total or partial mesorectal resection (with or without protective ileostomy) and completed a self-filled questionnaire over the phone to assess postoperative bowel dysfunction from January 2017 to December 2019. The predictors of LAR were evaluated using univariate and multivariate analyses.ResultThe study population was 566 patients, 264 (46.64%), 224 (39.58%), and 78 (13.78%) patients with no, minor, and major LARS, respectively. In the univariate analysis, independent factors such as tumor location and size, anastomotic height, protective ileostomy, post-operation chemoradiotherapy, tumor T stage, lymphatic nodal metastasis classification, surgery duration, and time interval for closure of stoma were significantly associated with LARS points while we found the tumor T stage and lymphatic nodal metastasis classification as the new independent risk factors compared with the last decade studies. In the multivariate analysis, factors such as low and middle tumor location and protective ileostomy, and post operation treatment, nodal metastasis classification were the independent risk factors for major LARS.ConclusionThe new independence risk factors were tumor T stage and lymphatic nodal metastasis status in univariate analysis in our study, with anastomotic height, low and middle tumor location, protective ileostomy, post-operation chemoradiotherapy, nodal metastasis status increasing LARS point in multivariate analysis after surgery for CRC.

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End-to-end anastomosis provides similar quality-of-life, compared with other reconstructive techniques six months following total mesorectal excision: Systematic review and meta-analysis

Kávási,

Iov,

Rancz

et al. 2024

European Journal of Surgical Oncology

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Surgical treatment of low anterior resection syndrome

Cited by 4 publications

References 27 publications

The Risk Factors of Low Anterior Resection Syndrome After Colorectal Cancer Surgery Compared with the Last Decade Studies

The Risk Factors of Low Anterior Resection Syndrome After Colorectal Cancer Surgery Compared with the Last Decade Studies

The risk factors of low anterior resection syndrome after colorectal cancer surgery: A retrospective study of 566 patients in a single institution in China

End-to-end anastomosis provides similar quality-of-life, compared with other reconstructive techniques six months following total mesorectal excision: Systematic review and meta-analysis

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