Surgical Treatment of Gastroesophageal Reflux in Children: A Combined Hospital Study of 7467 Patients

Fonkalsrud, Eric W.; Ashcraft, Keith W.; Coran, Arnold G.; Ellis, Dick G.; Grosfeld, Jay L.; Tunell, William P.; Weber, Thomas

doi:10.1542/peds.101.3.419

Cited by 240 publications

(187 citation statements)

References 14 publications

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“…29 In the present study, the observations of a major postoperative complication rate of 14.28% in each group and a minor complication rate of 28.57% in the VGP group are at the lower limit of the rates reported in the literature. The two deaths that occurred in the present study were unrelated to the surgical procedure.…”

Section: 24contrasting

confidence: 46%

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Vertical gastric plication versus Nissen fundoplication in the treatment of gastroesophageal reflux in children with cerebral palsy

2007

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RESULTS:The mean follow-up was 5.2 months; symptoms were reduced by 42.8% (NF) (p = 0.001) and 57.1% (VGP) (p = 0.006). The Boix-Ochoa score was favorable for both groups: NF (p < 0.001) and VGP (p < 0.042). The overall mortality was 14.28% in both groups and was due to causes unrelated to the surgical treatment. CONCLUSION:The two operative procedures were shown to be effi cient and effi cacious for the treatment of GERD in neuropathic patients, over the study period.

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Section: 24contrasting

confidence: 46%

“…20,24 Esophageal dysmotility, in association with the construction of a valve around the intra-abdominal portion of the esophagus, is the main agent responsible for the greater complication rate in these patients. 29 These symptoms may be persistent and diffi cult to treat, thus stimulating surgeons to seek new surgical alternatives.…”

Section: 24mentioning

confidence: 99%

Vertical gastric plication versus Nissen fundoplication in the treatment of gastroesophageal reflux in children with cerebral palsy

2007

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“…Apesar de ainda ser largamente usada, seu uso indiscriminado não é compatível com os conhecimentos atuais sobre a eficiência do tratamento farmacológico e com as altas taxas de falhas e morbidade cirúrgica 73 . Antes da indicação cirúrgica, a DRGE deve ser caracterizada como crônica e recorrente, sendo o paciente caracterizado como necessitando de IBP ao longo da vida.…”

Section: Tratamento Cirúrgico Da Drgeunclassified

Treatment of gastroesophageal reflux disease

Guimarães¹,

Marguet²,

Camargos³

2006

J Pediatr (Rio J)

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Objective: To review the literature on the treatment of gastroesophageal reflux disease (GERD) with emphasis on pharmacological aspects. To identify particularities of pharmacological treatment of esophageal and extraesophageal manifestations of the disease.Sources: Electronic search of the PubMed/MEDLINE and Cochrane Collaboration databases. Controlled and randomized studies published since 2000 and reviews representing consensus positions and directives published within the last 10 years were identified. Summary of the findings:The drugs currently available for the treatment of GERD do not act in the primary mechanism of the disease, i.e., transitory relaxation of the lower esophageal sphincter. Pharmacological treatment of GERD with symptoms or with esophageal injury is based on the suppression of acid secretion, particularly with proton pump inhibitors. When the hyperreactivity of the lower airways coexists with esophageal GERD symptoms, suppression of acid secretions should be of benefit in managing the respiratory disease in the presence of a causal relationship; however, this is not usual. When esophageal symptoms are not present, esophageal 24-hour pH study should be carried out prior to starting pharmacological treatment for GERD. Improvement of respiratory symptoms may be delayed with relation to esophageal symptoms. It is common for GERD to recur and pharmacological treatment should be repeated or continued indefinitely, depending on clinical presentation of the disease. Conclusions:The strategies that have been proposed for the pharmacological treatment of GERD in children are primarily based on studies of case series or on studies with adults. There have been very few controlled and randomized studies in children. Undertaking a greater number of these studies might reinforce existing aspects or establish new aspects of management.J Pediatr (Rio J). 2006;82(5 Suppl):S133-45: Gastroesophageal reflux, child, drug therapy, esophagitis, respiratory tract diseases, asthma. ResumoObjetivo: Rever a literatura sobre tratamento da doença do refluxo gastroesofágico (DRGE) com ênfase nos aspectos farmacológi-cos. Identificar particularidades do tratamento farmacológico nas manifestações esofágicas e extra-esofágicas da doença.Fontes de dados: Busca eletrônica na base de dados PubMed/ MEDLINE e Cochrane Collaboration. Procurou-se identificar estudos controlados e randomizados publicados a partir de 2000, bem como revisões que representassem consensos e diretrizes publicados nos últimos 10 anos.Síntese dos dados: Nenhuma das drogas atualmente usadas no tratamento da DRGE altera comprovadamente o mecanismo principal da doença, ou seja, os relaxamentos transitórios do esfíncter esofágico inferior. O tratamento farmacológico da DRGE com sintomas ou com lesões esofágicas é baseado na inibição da secreção ácida, em particular pelos inibidores da bomba de prótons (IBP). Nas situações em que a hiper-reatividade das vias aéreas inferiores coexiste com sintomas esofágicos da DRGE, a inibição da secreção ácida deve...

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“…Например, операция Ниссена является одним из наиболее распространенных хирургиче-ских вмешательств в детской хирургии. Она зани-мает третье место среди всех хирургических проце-дур, которые выполняются в детском возрасте [9]. Данные национального исследования из США де-монстрируют, что 45% антирефлюксных операций выполняются у детей в возрасте до 1 года [10].…”

Section: дискуссияunclassified

Endosurgical treatment of gastric diseases in newborns and infants

Kozlov¹,

Novozhilov²,

Mikhailov³

et al. 2015

Endosk. khir.

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25Операции на желудке составляют большую часть хирургических вмешательств на органах брюшной полости, которые выполняются у детей первых трех месяцев жизни. Спектр этих процедур у детей ран-него возраста достаточно широк и представлен в основном фундопликацией, гастростомией, пило-ромиотомией и гастрорафией.Опыт применения минимально инвазивного подхода в лечении заболеваний желудка у детей на-считывает чуть более 20 лет. Историческая публи-

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Surgical Treatment of Gastroesophageal Reflux in Children: A Combined Hospital Study of 7467 Patients

Cited by 240 publications

References 14 publications

Vertical gastric plication versus Nissen fundoplication in the treatment of gastroesophageal reflux in children with cerebral palsy

Vertical gastric plication versus Nissen fundoplication in the treatment of gastroesophageal reflux in children with cerebral palsy

Treatment of gastroesophageal reflux disease

Endosurgical treatment of gastric diseases in newborns and infants

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