Surgical Treatment of Culture-Negative Aortic Infective Endocarditis

Polat, Adil; Tuncer, Altug; Tuncer, Eylem; Mataracı, İlker; Aksoy, Eray; Dönmez, Arzu Antal; Balkanay, Mehmet; Zeybek, Rahmi; Yakut, Cevat

doi:10.1016/j.athoracsur.2011.08.067

Cited by 5 publications

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“…Brucellosis is an endemic disease in Turkey [23,24]. Endocarditis is an important fatal complication of brucellosis [40]. In this study 4.2% of the cases with etiology had Brucella endocarditis.…”

Section: Discussionmentioning

confidence: 50%

“…Underlying heart diseases in percentage (from references number:[6,15,19,20,[25][26][27][28][29][30][31][32][33][35][36][37]39,40],). Involved infection sites in cases (from references number:[6,15,19,20,[25][26][27]30,31,[33][34][35][36]39,40]). …”

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confidence: 99%

“…Summary of echocardiographic findings in percentage (and numbers). ,15,19,20,25,26,27,28,29,30,31,33,34,36,38,40] Vegetation 83.2% (n = 1132)[6,15,19,20,25,26,27,28,29,30,31,33,34,36,38,40] Endocarditis complications in percentage (and numbers).…”

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confidence: 99%

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Pooled analysis of 1270 infective endocarditis cases in Turkey

Vahabi

Gül

Garakhanova

et al. 2019

J Infect Dev Ctries

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Introduction: Despite developments in medicine, infective endocarditis (IE) is still associated with significant morbidity and mortality. In this study it was aimed to systematically review the infective endocarditis literature published or presented from Turkey. Methods: To find the published series, one national database (Ulakbim), and three international databases (Scopus, Pubmed and Sci-e) were searched between 31 October-3 November 2014. also, abstracts of congresses by three national congresses were searched for studies regarding infective endocarditis. Results: Data for 1270 patients (38.3% female, mean age 46.2, 28% prosthetic valve endocarditis) with a diagnosis of infective endocarditis were obtained from 21 reports (18 published articles and three congress abstracts). Of the 18 articles, four were in peer-reviewed medical journals indexed in national databases and 14 were in international databases. There was an underlying heart disease in 51.9% and history of dental procedure was 6.7%. Fever, heart murmur and fatigue were present in 94%, 71.4% and 69% respectively. most commonly involved site was mitral valve (43.3%), followed by aortic (33.8%) and tricuspid valve (6.4%). Staphylococcus aureus, coagulase-negative staphylococci and enterococci comprised the 22.8%, 9.7% and 7.5% of the cases while 31.1% were culture-negative. Overall mortality was 23.4%. When we compared series related to years 2008 and before and 2009 and after, the mortality rates were (24.1%-224/931) vs (20.1%-32/159), respectively (p = 0,31). Conclusion: Infective endocarditis is still associated with significant mortality. S. aureus seems to be the most common etiologic agent. There was a slight decrease in the recent years in mortality.

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Section: Discussionmentioning

confidence: 50%

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confidence: 99%

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Pooled analysis of 1270 infective endocarditis cases in Turkey

Vahabi

Gül

Garakhanova

et al. 2019

J Infect Dev Ctries

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“…First, we had a very high rate of culture-negative cases, and this was discussed in detail in a previous analysis. [18] Thus, our findings regarding the microorganisms must be viewed with caution. In addition, we had a low number of patients which did not allow us to perform a multivariable analysis.…”

Section: Discussionmentioning

confidence: 99%

Surgical treatment of aortic valve endocarditis with aortic annular involvement: a 26-years experience

Şişmanoğlu¹

2014

Turk Gogus Kalp Dama

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Amaç: Bu çalışmada aortik anülüsü etkileyen aort kapak endokarditinin cerrahi tedavisine ilişkin erken ve geç dönem sonuçlar bildirildi. Ça lış mapla nı:Aralık 1985 -Ocak 2011 tarihleri arasında toplam 42 ardışık hasta (32 erkek, 10 kadın; ort. yaş 39.0±13.3 yıl; dağılım 16-67 yıl) cerrahi bulgular ve uygulanan cerrahiler açısından retrospektif olarak incelendi. Hastaların 25'inde (%59.5) kan kültüründe üreme tespit edildi ve streptokok en çok (n=15, %35.7) tespit edilen mikroorganizma oldu. On dört hastanın (%33.3) tıbbi öyküsünde geçirilmiş kalp ameliyatı varken, 13 hastada (%31) protez kapak endokarditi vardı. Ortalama takip süresi 7.9±4.4 (dağılım 0.1-18.2 yıl) yıl idi. Bul gu lar: Hastaların tümüne toplam 64 cerrahi işlem uygulandı. Yirmi altı (%61.9) hasta ile aort kapak replasmanı en sık uygulanan işlem iken, bunu 15 hasta ile aort kök replasmanı ve bir hasta (%2.4) ile periprostetik kaçağın primer onarımı takip etti. Dokuz hastaya (%21.4) eş zamanlı mitral kapak işlemi yapıldı. Hastane mortalitesi dokuz hastada (%21.4) görüldü. Ameliyat sonrası yedi hastada (%16.7) düşük kalp debisi, altı hastada (%14.3) ise kalp bloku gelişti, fakat yalnızca iki hastada kalıcı kalp pili kullanımı gerekti. Hastaların hesaplanan bir, beş ve 10 yıllık sağkalım oranları sırasıyla %80.0±6.3, %69.9±7.3 ve %64.9±8.3 idi. So nuç:Aortik anülüsü etkileyen aort kapak endokarditi cerrahisi yüksek hastane mortalitesine sahip olsa da, yaşayan hastaların uzun dönem sağkalımları tatmin edicidir.Anah tar söz cük ler: Anülüs; aort kapak; endokardit.Background:In this study, we report early and late results of surgical treatment of aortic valve endocarditis with aortic annular involvement. Methods: Between December 1985 and January 2011, 42 consecutive patients (32 males, 10 females; mean age 39.0±13.3 years; range 16 to 67 years) were retrospectively analyzed in terms of surgical findings and operative procedures. The blood cultures were positive in 25 patients (59.5%) and the most commonly identified microorganism was streptococcus (n=15, 35.7%). Fourteen patients (33.3%) had a medical history of previous cardiac surgery and 13 (31.0%) had prosthetic valve endocarditis. The mean duration of follow-up were 7.9±4.4 years (range 0.1 to 18.2 years). Results: All patients underwent a total of 64 surgical procedures. The most commonly performed procedure was aortic valve replacement with 26 patients (61.9%), followed by aortic root replacement in 15 (35.7%) and primary repair of periprosthetic leakage in one patient (2.4%). Nine patients (21.4%) had concomitant procedures for the mitral valve. In-hospital mortality was seen in nine patients (21.4%). Postoperatively seven patients had (16.7%) low cardiac output, six had (14.3%) heart block, however, only two of them required permanent pacemaker. The actuarial survival rates at one, five and 10 years were 80.0±6.3%, 69.9±7.3% and 64.9±8.3%, respectively. Conclusion:Although surgery for aortic valve endocarditis with annular involvement has high in-hospital mortality rate, long-term survival is ...

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Invited Commentary

SampathKumar¹

2012

The Annals of Thoracic Surgery

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Surgical Treatment of Culture-Negative Aortic Infective Endocarditis

Cited by 5 publications

References 16 publications

Pooled analysis of 1270 infective endocarditis cases in Turkey

Pooled analysis of 1270 infective endocarditis cases in Turkey

Surgical treatment of aortic valve endocarditis with aortic annular involvement: a 26-years experience

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