Surgical Treatment of Acute Periprosthetic Knee Infection with Concurrent Presumed COVID-19

Sunkin, Jonathan A; Lindsey, Matthew H; Stenquist, Derek S; Fuller, Brian C.; Chen, Antonia F.; Shah, Vivek M.

doi:10.2106/jbjs.cc.20.00226

Cited by 3 publications

(4 citation statements)

References 3 publications

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“…The characteristics of included trials were presented in Table 1 . A total of 269 patients from 47 studies [16] , [17] , [18] , [19] , [20] , [21] , [22] , [23] , [24] , [25] , [26] , [27] , [28] , [29] , [30] , [31] , [32] , [33] , [34] , [35] , [36] , [37] , [38] , [39] , [40] , [41] , [42] , [43] , [44] , [45] , [46] , [47] , [48] , [49] , [50] , [51] , [52] , [53] , [54] , [55] , [56] , [57] , [58] , [59] , [60] , [61] , [62] were included in our meta-analysis. The mean age of operative patients with COVID-19 was 50.91 [95% CI, 42.49; 59.34], and 49% [95% CI, 0.33, 0.65] patients were female.…”

Section: Resultsmentioning

confidence: 99%

“…Of the 47 studies included in the analysis, only 20 studies [ 16 , [18] , [19] , [20] , 24 , 25 , 29 , 32 , 39 , 42 , 45 , 46 , 50 , 53 , [55] , [56] , [57] , [58] , [59] , 61 ] reported the information of medical staff infection which identified that a total of 38 medical staff were infected, and medical staff who used biosafety level 3 (BSL-3) protective equipment during the perioperative period did not get infected.…”

Section: Resultsmentioning

confidence: 99%

See 1 more Smart Citation

Factors affecting the mortality of patients with COVID-19 undergoing surgery and the safety of medical staff: A systematic review and meta-analysis

Wang¹,

Wu²,

Xu³

et al. 2020

EClinicalMedicine

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Background The 2019 novel coronavirus disease (COVID-19) can complicate the perioperative course to increase postoperative mortality in operative patients, and also is a serious threat to medical staff. However, studies summarizing the impact of COVID-19 on the perioperative mortality of patients and on the safety of medical staff are lacking. Methods We searched PubMed, Cochrane Library, Embase and Chinese database National Knowledge Infrastructure (CNKI) with the search terms “COVID-19″ or “SARS-CoV-2″ and “Surgery” or “Operation” for all published articles on COVID-19 from December 1, 2019 to October 5, 2020. Findings A total of 269 patients from 47 studies were included in our meta-analysis. The mean age of operative patients with COVID-19 was 50.91 years, and 49% were female. A total of 28 patients were deceased, with the overall mortality of 6%. All deceased patients had postoperative complications associated with operation or COVID-19, including respiratory failure, acute respiratory distress syndrome (ARDS), short of breath, dyspnea, fever, cough, fatigue or myalgia, cardiopulmonary system, shock/infection, acute kidney injury and severe lymphopenia. Patients who presented any or more of the symptoms of respiratory failure, ARDS, short of breath and dyspnea after operation were associated with significantly higher mortality ( r = 0.891, p < 0.001), while patients whose symptoms were presented as fever, cough, fatigue or myalgia only demonstrated marginally significant association with postoperative mortality ( r = 0.675, p = 0.023). Twenty studies reported the information of medical staff infection, and a total of 38 medical staff were infected, and medical staff who used biosafety level 3 (BSL-3) protective equipment did not get infected. Interpretation COVID-19 patients, in particular those with severe respiratory complications, may have high postoperative mortality. Medical staff in close contact with infected patients is suggested to take high level personal protective equipment (PPE). Funding Heilongjiang postdoctoral scientific research developmental fund and the National Natural Science Foundation of China.

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Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Factors affecting the mortality of patients with COVID-19 undergoing surgery and the safety of medical staff: A systematic review and meta-analysis

Wang¹,

Wu²,

Xu³

et al. 2020

EClinicalMedicine

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“…Studies were excluded if they reported tracheostomy outcomes only; did not involve a surgical intervention; the diagnosis of COVID-19 was based on symptoms or X-ray findings only; did not 16 Paris Urology All Yes Di Martino 17 Spain Gen Surg All Yes Alvarez Gallego 18 Spain Gen Surg All Yes Kayani 19 UK Ortho Emergency Yes Egol 20 USA Ortho Emergency Yes Cai 21 China Gen Surg Emergency Yes Javanmard-Emamghissi 22 UK Gen Surg Emergency Yes Barkhordari 23 Iran Cardiac Emergency Yes Sobti 24 UK Trauma/Orthopaedics Emergency Yes COVIDSurg Collaborative 8 Global All All No Dai 25 China Cancer Elective No Lei 26 China All Elective No Shrikhande 27 India Cancers Elective No Aminian 28 Iran Gen Surg Elective No Zhong 29 China Ortho/Gynae Emergency No Munoz Vives 30 Spain Ortho Emergency No Bellosta 31 Italy Vascular Emergency No Chen 32 China Caesarean Section Emergency No Senent-Boza 33 Spain All Emergency No Barret 34 Spain Burns Emergency No Hussain 35 London Cardiac Emergency No Li 36 China Thoracic Not stated No Case reports Gou, SM 37 China Pancreas Emergency Garcia-Portabella 38 Spain Ortho Emergency Davis-Sandfoss 39 USA Breast Cancer Elective Han 40 China Thoracic Emergency Lepre 41 Italy General Surgery Emergency Lyra 42 Portugal Obstetrics Elective Powezka 43 UK Vascular Emergency Qin 44 China Liver Transplant Emergency Rinaldi 45 Italy Vascular Emergency Stevenson 46 UK Ortho cancers Elective Sunkin 47 USA Orthopaedics Emergency Wen 48 China Neurosurgery Emergency Xuan 49 China Lung Transplant Emergency report on surgical outcomes; were incidence only studies, practice guidelines, consensus stateme...…”

Section: Inclusion and Exclusion Criteriamentioning

confidence: 99%

Mortality of patients with COVID‐19 who undergo an elective or emergency surgical procedure: a systematic review and meta‐analysis

Brown

Moore

Watters

2020

ANZ Journal of Surgery

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This meta‐analysis demonstrated that the odds ratio for mortality in patients who underwent a surgical procedure while coronavirus disease 2019 (COVID‐19) positive was 7.9 (95% confidence interval: 3.2–19.4) when compared with patients who were not COVID positive. This confirms findings from uncontrolled cohort studies and mandates health systems to seek ways to reduce the risk of operating on patients with COVID‐19, and when surgery is necessary, provide an environment where close monitoring for complications will enable early intervention.

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“…One clinical case was found by authors as a result of the literature search on the topic in the PubMed and MEDLINE databases ( 16 ). This clinical case describes a patient with comorbid background with COVID-19 infection and PJI, and its management in the operating room.…”

Section: Discussionmentioning

confidence: 99%

Case Report: Complex Treatment Using Vibroacoustic Therapy in a Patient With Co-Infection and COVID-19

et al. 2022

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The present report highlights a case of successful treatment of a 59-year-old patient who experienced pain, swelling, hyperemia, the presence of a wound of the right knee joint, impaired function of the right lower limb, weakness, fatigue, and labored breathing. Sepsis was detected in the patient as a result of periprosthetic infection with concomitant severe COVID-19. The patient was admitted to the hospital for 59 days, with 57 days of treatment of the patient at the intensive care unit. A therapy of multiple organ failure involved complex treatment using antiviral and combined antibiotic therapy, taking into account the sensitivity of the pathogen to antibiotics; glucocorticoid therapy; anticoagulant therapy; the concept of non-invasive ventilation; and vibroacoustic pulmonary therapy as a method of physiotherapy as well. An integrated approach using a vibroacoustic device in the therapy of the patient with sepsis due to periprosthetic infection with concomitant coronavirus infection had a positive effect despite the lack of etiological treatment against the COVID-19.

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Surgical Treatment of Acute Periprosthetic Knee Infection with Concurrent Presumed COVID-19

Cited by 3 publications

References 3 publications

Factors affecting the mortality of patients with COVID-19 undergoing surgery and the safety of medical staff: A systematic review and meta-analysis

Factors affecting the mortality of patients with COVID-19 undergoing surgery and the safety of medical staff: A systematic review and meta-analysis

Mortality of patients with COVID‐19 who undergo an elective or emergency surgical procedure: a systematic review and meta‐analysis

Case Report: Complex Treatment Using Vibroacoustic Therapy in a Patient With Co-Infection and COVID-19

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