Surgical treatment of 45 horses affected by squamous cell carcinoma of the penis and prepuce

Abstract

Summary The medical records of 45 horses treated for suspected squamous cell carcinoma of the penis and/or prepuce were reviewed. The age of 40 horses was known, and these had a mean age of 17.4 years. The duration of neoplasia was known foronly 3 of the 45 horses. The results of histological evaluation of lesions, available for 35 horses, confirmed that the diseased tissue was squamous cell carcinoma. The location of gross neoplastic lesions was recorded for 43 horses; the glans penis was involved in 24 horses, the body of the penis or the inner lamina of the preputial fold in 27 horses, and the external fold of the prepuce in 10 horses. Surgical treatments of these horses included phallectomy (penile amputation) in 35 horses, segmental posthectomy in 4 horses, phallectomy plus segmental posthectomy in 2 horses, and en bloc resection of the penis, prepuce and superficial inguinal lymph nodes with penile retroversion in 4 cases. Short‐term complications in the immediate postoperative period included preputial oedema and haemorrhage at the end of urination. One horse developed acute urinary retention because of severe urethral oedema. Long‐term (>1 year) follow‐up information was obtained for 31 horses. Neoplasia of the penis and/or prepuce recurred in 6 of these 31 horses (19%), and in 5 of these the recurrence necessitated euthanasia of the horse.

Use of a modified Vinsot technique for partial phallectomy in 11 standing horses

“…4-7 Partial phallectomy is generally regarded as a salvage procedure in stallions and is commonly performed with the horse anesthetized to facilitate surgery. 14,15 Intermittent hemorrhage at the end of urination is expected postoperatively and may persist for up to 5 weeks before it resolves spontaneously. Horses with more extensive lesions involving the internal preputial lamina require a phallectomy with en bloc resection with or without penile retroversion.…”

Estudo retrospectivo de fimose traumática em equinos e tratamento utilizando a técnica de circuncisão com encurtamento de pênis (1982-2007)

“…A ocorrência de traumas envolvendo o pênis e prepúcio são causas comuns de infertilidade em garanhões (MACKINNON & VOSS, 1992). Os traumatismos produzidos na genitália externa são considerados uma condição de risco para os garanhões e devem ser tratadas como emergência a fim de se evitar danos à espermatogênese, à habilidade de realização da cópula e em especial à ejaculação do animal (PERKINS & FRAZER, 1994).…”

“…A técnica de circuncisão com encurtamento do pênis é indicada na preparação de rufiões equinos, remoção de neoplasias, granulomas e excesso de tecido cicatricial como em fimoses (TURNER & MCILWRAITH, 1985;MAIR et al, 2000). Esta técnica apresenta um período de intervenção curto, poucos planos anatômicos atingidos, fácil reconstrução da ferida cirúrgica, além de poder ser realizada a campo (SILVA et al, 1995).…”

A Penile Squamous Cell Carcinoma With Systemic Metastasis in a Thoroughbred Horse

“…[6][7][8] Peritoneal metastasis of PSCC has been reported in one human case and occasionally in equine PSCC studies without detailed information. 7,8 Herein, we describe a case of peritoneal carcinomatosis from PSCC, con¯rmed by immunohistochemistry (IHC), in a Thoroughbred horse. Pathogenesis of PSCC and precancerous lesions is also discussed.…”

“…6 Distant metastasis of PSCC is rare occurring most often in the lungs and liver, 6 and the peritoneal metastasis (peritoneal carcinomatosis) of PSCC is extremely rare. [6][7][8] Peritoneal metastasis of PSCC has been reported in one human case and occasionally in equine PSCC studies without detailed information. 7,8 Herein, we describe a case of peritoneal carcinomatosis from PSCC, con¯rmed by immunohistochemistry (IHC), in a Thoroughbred horse.…”