The differential diagnosis of cystic adnexal masses, some placed retroperitoneally, includes various pathologies. Preoperative diagnosis is important to prevent major neurological deficits during surgery. Herein, we present a case of anterior sacral meningocele diagnosed in an infertile woman using magnetic resonance imaging (MRI) and eliminated with surgery. An MRI performed to determine the origin of retroperitoneal fixated masses helps direct the patient to the right consultant department and may avoid an inappropriate surgical approach, which may lead to a failure. A retroperitoneal mass, such as anterior sacral meningocele, may contribute to the pathogenesis of infertility by distorting the utero-tuboovarian anatomy.