Surgical resection of metastatic intraventricular tumors

Choroid Plexus Metastasis of Follicular Thyroid Carcinoma Diagnosed due to Intraventricular Hemorrhage

“…On the other hand, metastases to the brain parenchyma are frequently reported to originate from lung, breast and colon cancers, whereas kidney and thyroid lesions account for only 5.3% and 0.9-1.5% of cases, respectively (Table 2) (1, 6, 12, 34). The higher incidence of CPM derived from RCC suggests that there may be a tropism of this tumor type for the ventricle, possibly due to the structural similarity of the kidney and choroid plexus, as both organs act as plasma-filtering systems (38). Similarly, the increased tendency of thyroid cancers to be a more common source of CPM than brain metastases suggests that thyroid cancer cells possess a biological affinity to the choroid plexus.…”

Stereotactic Radiosurgical Treatment of Brain Metastases to the Choroid Plexus

“…Most metastases are found in the brain parenchyma and, to a lesser degree, the dura and leptomeninges (8). Metastases to the choroid plexus are rare and have generally been reported singly or in groups up to four cases, more to illustrate an uncommon lesion or a technique rather than to outline a comprehensive management approach (10)(11)(12)(13)(14)(15)(16)(17)(18). To date, no consensus for treating CPMs has been developed.…”

“…Similarly, patients with lesions deep in the brain, in eloquent areas, or with multiple tumors are frequently excluded as candidates for surgery because of the potential for injury of normal, intervening neural structures, which may sometimes lead physicians to prefer WBRT over SRS as well (2,3,(27)(28)(29). Most surgical approaches to the lateral and third ventricles require either a transcortical or transcallosal approach and lesions in the fourth ventricle often require splitting the cerebellar vermis, which may increase operative morbidity (2,10). Less invasive treatment strategies to lesions in this area would be welcome.…”

“…CPMs from any primary source have only rarely been reported (2,8,(10)(11)(12)(13)(14)(15)(16)(17)(18)(19). Because of their rarity and their anatomic location, no consensus has been developed regarding optimal management.…”

“…Choroid plexus metastases (CPM) from any primary source are rare (8,10). Most cases of CPMs reported previously have been identified in patients with RCC, have been described individually, and have been treated with a variety of management modalities, including surgery, whole-brain radiation therapy (WBRT), stereotactic radiosurgery (SRS), or a combination (10)(11)(12)(13)(14)(15)(16)(17)(18)(19). No study has reported a comprehensive series of patients treated with a single strategy.…”