Surgical intervention strategies for pediatric congenital cystic lesions of the lungs: A 20-year single-institution experience

Furukawa, Taiji; Kimura, Osamu; Sakai, Kazuhisa; Higashi, Michiyo; Fumino, Shigehisa; Aoi, Shigeyoshi; Tajiri, Tatsuro

doi:10.1016/j.jpedsurg.2015.08.019

Cited by 11 publications

(9 citation statements)

References 16 publications

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“…MINORS scores of nine single-arm studies were higher than 10 points and with high qualities. [34][35][36]40,42,45,46,48,50 Correlation between symptomatic percentage and conversion using VATS A total of 11 studies were involved for Pearson analysis, which was used to evaluate the correlation between percentage of symptomatic cases and conversion in patients who underwent VATS. It turned out that the Pearson correlation coefficient was 0.92 (95% CI, 0.71-0.98, P < 0.0001) and R square was 0.84 (Figure 5A).…”

Section: Risk Of Biasmentioning

confidence: 99%

Is thoracoscopy superior to thoracotomy in the treatment of congenital lung malformations? An updated meta-analysis

Xie¹,

2020

Ther Adv Respir Dis

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Background: A meta-analysis was performed for a comparison of outcomes between video-assisted thoracoscopic surgery (VATS) and thoracotomy for congenital lung malformations (CLM). Methods: Electronic databases, including PubMed, Scopus, Embase, and the Cochrane Library were searched systematically for literature aimed mainly at reporting the therapeutic effects for CLM administrated by VATS and thoracotomy. Results: A total of 40 studies meeting the inclusion criteria were included, involving 2896 subjects. VATS was associated with fewer complications [odds ratio (OR) 0.54; 95% confidence interval (CI), 0.42–0.69], less use of epidural anesthesia (OR, 0.08; 95% CI, 0.03–0.23), shorter length of hospital stay [standard mean difference (SMD) −0.98; 95% CI, −1.4 to −0.55] and chest drainage (SMD, −0.43; 95% CI, −0.7 to −0.17), as compared with thoracotomy. However, thoracotomy showed superiority in reduced operative time (SMD, 0.44; 95% CI, 0.04–0.84). Pearson analysis (Pearson r = 0.85, 95% CI, 0.28 to 0.98, p = 0.01) and linear regression ( R square 0.73) confirmed a positive correlation between percentage of symptomatic cases and conversion in patients using VATS. Conclusion: VATS is associated with fewer complications, less use of epidural anesthesia, shorter length of stay and length of chest drainage, but longer operative time, as compared with thoracotomy. Symptomatic patients with CLM using VATS may be prone to conversion to thoracotomy. The reviews of this paper are available via the supplemental material section.

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Section: Risk Of Biasmentioning

confidence: 99%

Is thoracoscopy superior to thoracotomy in the treatment of congenital lung malformations? An updated meta-analysis

Xie¹,

2020

Ther Adv Respir Dis

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“…Surgery is recommended for all complex foregut malformations due to the risk of malignancy as well as increased difficulty and risk with resection due to inflammation if surgery is delayed until the patient becomes symptomatic with recurrent infections . For CPAMs specifically, surgical resection is recommended, but the timing remains controversial.…”

Section: Discussionmentioning

confidence: 99%

A congenital cystic pulmonary airway malformation occurring together with both an extralobar pulmonary sequestration and an esophageal duplication cyst

Dewberry

Trecartin

Galambos

et al. 2019

Clinical Case Reports

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A foregut duplication cyst occurring together with both a congenital cystic pulmonary airway malformation and extralobar pulmonary sequestration is an unusual combination. Prenatal ultrasound, MRI, and postnatal CT are helpful for operative planning. Surgical resection is the definitive management for all three anomalies. K E Y W O R D Scystic lung disease, cystic pulmonary airway malformation, esophageal duplication cyst, extralobar pulmonary sequestration, prenatal imaging

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“…While the patient described in this report was surgically treated because of his symptoms, asymptomatic pediatric patients with CPAM should undergo regular radiological monitoring, with consideration of elective surgery if necessary. 15) …”

Section: Discussionmentioning

confidence: 99%

Case of mucinous adenocarcinoma of the lung associated with congenital pulmonary airway malformation in a neonate

et al. 2018

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Congenital pulmonary airway malformation (CPAM), previously known as congenital cystic adenomatoid malformation, is a rare developmental lung abnormality associated with rhabdomyosarcoma, pleuropulmonary blastoma, and mucinous adenocarcinoma of the lung. We report an unusual case of a 10-day-old male newborn with a left lower lobe pulmonary cyst who underwent lobectomy, which revealed type II CPAM complicated by multifocal mucinous adenocarcinoma. KRAS sequencing revealed a somatic mutation in Codon12 (GGT → GAT), suggesting the development of a mucinous adenocarcinoma in the background of mucinous metaplasia. Mucinous adenocarcinoma is the most common lung tumor associated with CPAM, but it generally occurs in older children and adults. Further, all cases in the literature are of type I CPAM. This case in a neonate indicates that malignant transformation can occur very early in type II CPAM.

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Surgical intervention strategies for pediatric congenital cystic lesions of the lungs: A 20-year single-institution experience

Cited by 11 publications

References 16 publications

Is thoracoscopy superior to thoracotomy in the treatment of congenital lung malformations? An updated meta-analysis

Is thoracoscopy superior to thoracotomy in the treatment of congenital lung malformations? An updated meta-analysis

A congenital cystic pulmonary airway malformation occurring together with both an extralobar pulmonary sequestration and an esophageal duplication cyst

Case of mucinous adenocarcinoma of the lung associated with congenital pulmonary airway malformation in a neonate

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