Surgical Antibiotic Prophylaxis in a Turkish University Hospital

Yalcin, Ata Nevzat; Serin, Salih; Gürses, Ercan; Zencir, Mehmet

doi:10.1179/joc.2002.14.4.373

Cited by 25 publications

(32 citation statements)

References 10 publications

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“…Similar studies conducted in other countries (8)(9)(10)(11)(12)(13)(14)(15)(16), revealed a high frequency of prescription of antibiotics when not required, inappropriate choice, and use of antibiotics for a prolonged duration. In the current study too, a similar prescription pattern was found, where 3rd generation cephalosporins were prescribed to all patients preoperatively.…”

Section: Discussionsupporting

confidence: 71%

Antibiotic Prescription Pattern in Surgical Wards of MGM Hospital, Kamothe

Sane¹,

Shahani²,

Kalyanshetti³

2018

Int J Infect

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Background: Surgical antimicrobial prophylaxis refers to a brief course of antibiotic given just before surgery. Surgical site infection increases the hospital stay and prophylaxis has the potential to shorten hospital stay and fasten return to normal activity after discharge from the hospital. Therefore, the present study was undertaken to observe and analyse antimicrobial prescription pattern in patients that had undergone surgery at a tertiary care hospital. Methods: This was a prospective case series study, with 200 patients irrespective of age or gender, presented to the surgical wards of a tertiary hospital and undergoing surgical intervention, conducted from October 2016 to April 2017. Permission of the institutional ethics committee was obtained before commencement of the study. Data was collected from all patients with the help of predesigned, pretested, and structured questionnaires. By comparison with international guidelines and national guidelines, the antibiotic prescription patterns were assessed. The researchers also observed whether a fixed protocol was followed for antimicrobial use for surgical prophylaxis. Results: Overall, 200 patients were studied, with a mean age of 40.2 and a range of 23 to 70 years old with 64% being males and 36% being females. The surgeries of these patients were hernioplast 36%, PCNL 8%, haemorrhoidectomy 20%, appendicectomy 4%, hydrocoel surgery 16%, lipoma excision 12%, and cholecystectomy 4%. The percentages of antibiotics used for these surgeries were cefotaxime 44%, amikacin 88%, ceftriaxone 52%, metronidazole 30%, and cefixime 54%. These were then compared with the International and National guidelines for surgical prophylaxis. Conclusions: Third generation cephalosporins were the preferred antibiotics for pre-operative use as well as for use in combination with aminoglycoside and metronidazole for better postoperative antibiotic coverage. This seems to be due to multiple factors in Indian settings, which makes Indian practitioners administer antibiotics for a prolonged duration.

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Section: Discussionsupporting

confidence: 71%

Antibiotic Prescription Pattern in Surgical Wards of MGM Hospital, Kamothe

Sane¹,

Shahani²,

Kalyanshetti³

2018

Int J Infect

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“…Several studies assessing compliance with surgical prophylaxis guidelines in hospitals abroad have been published [6][7][8][9][10][11][12][13][14][15][16][17][18][19][20][21][22][23][24]. Overall compliance to guidelines has varied from as low as 0-53%, usually in the range of 20-30%.…”

Section: Discussionmentioning

confidence: 99%

How good is compliance with surgical antibiotic prophylaxis guidelines in a tertiary care private hospital in India? A prospective study

Parulekar¹,

Soman

Singhal

et al. 2009

Indian J Surg

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Purpose There is a need to study compliance with surgical antibiotic prophylaxis guidelines in India.Methods In this prospective study, 100 consecutive surgical procedures performed at a tertiary care private hospital in Mumbai, India were observed. The choice of antibiotic, timing and duration of administration were recorded and compared to the hospital guidelines.Results Appropriateness of choice of antibiotic was seen in 68%, timing in 89%, dose in 75% and duration in 63% of cases. Hundred percent compliance to all criteria was observed in 52% of cases. The SSI rate was 3.3%.Conclusions These compliance rates though suboptimal are similar to those reported in world literature. There is an urgent need to improve compliance with optimal surgical antibiotic prophylaxis guidelines so as to reduce risk of SSI and to prevent resistance and costs potentially associated with antibiotic misuse.

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“…Studien zur Compliance bestätigten die Notwendigkeit, evidenzbasierte Maß-nahmen konsequent umzusetzen: In einer Studie von Pons-Busom et al [44] wurde die Compliance für die perioperative Antibiotikaprophylaxe (PAP) mit 80% ermittelt, wobei in einer anderen Studie der richtige Zeitpunkt nur in 29% der Fäl-le eingehalten wurde [56]. In einer prospektiven, doppelblinden Kohortenstudie wurde durch Einführung einer neuen Strategie die Compliance zur zeitgerechten PAP von 5,9% auf 92,6% und der perioperativen Normothermie von 60,5% auf 97,6% verbessert [16].…”

Section: Allgemeine Grundsätze Der Ssi-präventionunclassified

Hygiene am Operationstisch

Krämer

2011

Trauma Berufskrankh

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HintergrundIm Ergebnis einer retrospektiven Erhebung der DKG (Deutsche Krankenhausgesellschaft, [11]) betrug die SSI-Inzidenz (SSI: "surgical site infections") in der Allgemeinchirurgie 7,1% und in der Abdominalchirurgie 13,5%. Im OP-KISS [40] betrug sie im Zeitraum 2005-2009 z. B. für laparoskopisch operierte Leistenhernien 0,23%, für offen operierte Leistenhernien 0,6% und für die laparoskopische Kolonchirurgie 4,6%.Durch Fall-Kontroll-Studien konnte gezeigt werden, dass Patienten mit postoperativen Wundinfektionen ein 2-fach höheres Sterblichkeitsrisiko haben, die Wahrscheinlichkeit der Intensivpflichtigkeit um 60% erhöht ist und sich die Aufenthaltsdauer in der Klinik um etwa 6,5 Tage verlängert [28]. Vor diesem Hintergrund ist die Ausschöpfung aller Mög-lichkeiten zur Prävention von SSI sowohl eine ethische Herausforderung als auch ökonomisch relevant. Allgemeine Grundsätze der SSI-Prävention

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Surgical Antibiotic Prophylaxis in a Turkish University Hospital

Cited by 25 publications

References 10 publications

Antibiotic Prescription Pattern in Surgical Wards of MGM Hospital, Kamothe

Antibiotic Prescription Pattern in Surgical Wards of MGM Hospital, Kamothe

How good is compliance with surgical antibiotic prophylaxis guidelines in a tertiary care private hospital in India? A prospective study

Hygiene am Operationstisch

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