How good is compliance with surgical antibiotic prophylaxis guidelines in a tertiary care private hospital in India? A prospective study

Parulekar, Lipika; Soman, Rajeev; Singhal, Tanu; Rodrigues, Camilla; Fd, Dastur; Mehta, Ajita

doi:10.1007/s12262-009-0004-9

Cited by 40 publications

(43 citation statements)

References 18 publications

(17 reference statements)

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“…Similar finding was found in study from Sudan (56.3%) [14]. There is false belief that broad/multiple antibiotics are more effective in preventing SSIs [15].…”

Section: Discussionsupporting

confidence: 84%

“…Furthermore, studies from different countries have found that SAP was used excessively and inappropriately [8][9][10][11][12][13][14][15][16][17][18][19]. A wide variation of overall compliance was seen that range from 0 to 71.9% in various surgical procedures, majority of these studies revealed that noncompliance were in terms of selection, timing of administration and prolonged duration of SAP; indication and dose of SAP were more satisfactory compliant than other parameters [20].…”

Section: Introductionmentioning

confidence: 99%

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Utilization Assessment of Surgical Antibiotic Prophylaxis at Ayder Referral Hospital, Northern Ethiopia

Mohamoud¹,

Yesuf²

2016

J App Pharm

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“…Similar finding was found in study from Sudan (56.3%) [14]. There is false belief that broad/multiple antibiotics are more effective in preventing SSIs [15].…”

Section: Discussionsupporting

confidence: 84%

Section: Introductionmentioning

confidence: 99%

Utilization Assessment of Surgical Antibiotic Prophylaxis at Ayder Referral Hospital, Northern Ethiopia

Mohamoud¹,

Yesuf²

2016

J App Pharm

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“…Studies conducted in Asian countries have generally reported higher prevalence of inappropriate antibiotic use for prophylaxis (48-100%) when compared to developed countries (23.4%-55.2%) [15,16,17,18,19]. Inappropriate timing of antibiotic administration (36.4%) and inappropriate duration (34.5%) were found to be the main reasons for inappropriate prophylactic antibiotic which was also similar to previous studies [17,18,20]. The inappropriate timing of administration in our setting was most likely due to the lack of local institutional guidelines.…”

Section: Discussionmentioning

confidence: 99%

Antibiotics in surgical wards: use or misuse? A newly industrialized country’s perspective

Lim

Lai

Ponnampalavanar

et al. 2015

J Infect Dev Ctries

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Introduction: Studies exploring the appropriateness of therapeutic antibiotic use among surgical patients are limited, particularly in developing countries. Therefore, the aim of our study was to determine the appropriateness of antibiotics prescribed in a surgical setting in Malaysia. Methodology: A prospective observational study was conducted in two surgical wards at a tertiary hospital in Malaysia from November 2012-July 2013. Data was collected using a case report form. The appropriateness of antibiotic therapy was based on compliance with either the Malaysian National Antibiotic Guidelines 2008 or International Clinical Practice Guidelines and determined by an expert panel (consisting of two infectious disease consultants and a pharmacist). Results: Over the study period, a total of 593 antibiotic courses were prescribed for 129 patients (4.6±3.4 antibiotics/patient). Only 34 (26.4%) patients received appropriate antibiotic therapy, whilst 95 (73.6%) patients received at least one course of inappropriate antibiotic therapy. The prevalence of inappropriate antibiotic use was 214 (66.3%) and 55 (42.0%) for prophylactic and therapeutic purposes, respectively. The most common causes of inappropriate prophylactic antibiotics were inappropriate timing 20 (36.4%) and inappropriate duration of prophylaxis 19 (34.5%). In cases of inappropriate timing, 9 (45%) were administered too late while 6 (30%) were too early. . In contrast, inappropriate choice of antibiotics (42.1%) and inappropriate indication (40.7%) were the most common reasons encountered for inappropriate therapeutic antibiotics. Conclusion: Our study suggests considerable inappropriate use of both prophylactic and therapeutic antibiotics in the surgical wards; highlighting an urgent need for antibiotic stewardship initiatives in this setting.

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“…6 However, despite the presence of evidence-based guidelines, poor adherence to guidelines has been reported internationally. [7][8][9][10][11][12][13] The King Hussein Cancer Centre (KHCC) in Amman, Jordan, is a 170-bed comprehensive teaching cancer centre with a surgical service consisting of nine teams with various specialties. Among these teams, an average of 25 patients are seen and five major elective surgeries are performed per day.…”

mentioning

confidence: 99%

Improvement in Adherence to Surgical Antimicrobial Prophylaxis Guidelines after Implementation of a Multidisciplinary Quality Improvement Project

Telfah¹,

Nazer²,

Dirani³

et al. 2015

SQUMJ

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abstract:Objectives: This study aimed to show the impact of a multidisciplinary quality improvement project on adherence to antimicrobial prophylaxis guidelines in oncological surgery. Methods: This pre-and post-intervention prospective observational study was carried out at the King Hussein Cancer Centre (KHCC) in Amman, Jordan, between August 2009 and February 2012. The quality improvement project consisted of revising the institutional guidelines for surgical antimicrobial prophylaxis, assigning a clinical pharmacist to the surgical department, establishing an operating room satellite pharmacy and providing education regarding the appropriate utilisation of antibiotics. The medical records of adult cancer patients who underwent surgery were evaluated one month before and one month after the project was implemented to assess adherence to the guidelines with regards to antibiotics prescribed, drug doses and timing and treatment duration. Results: A total of 70 patients were evaluated before and 97 patients were evaluated after the intervention, of which 57 (81.4%) and 95 (97.9%) patients received antibiotics, respectively. In comparing the pre-and post-intervention groups, an improvement was observed in the proportion of patients who received antibiotics at the appropriate time (n = 12 versus n = 79; 21.1% versus 83.2%; P <0.01), for the appropriate duration of time (n = 22 versus n = 94; 38.6% versus 99.0%; P <0.01) and in the appropriate dose (n = 9 versus n = 87; 56.3% versus 98.9%; P <0.01). Conclusion: Adherence to the antimicrobial prophylaxis guidelines at KHCC improved significantly after the implementation of a quality improvement project.

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How good is compliance with surgical antibiotic prophylaxis guidelines in a tertiary care private hospital in India? A prospective study

Cited by 40 publications

References 18 publications

Utilization Assessment of Surgical Antibiotic Prophylaxis at Ayder Referral Hospital, Northern Ethiopia

Utilization Assessment of Surgical Antibiotic Prophylaxis at Ayder Referral Hospital, Northern Ethiopia

Antibiotics in surgical wards: use or misuse? A newly industrialized country’s perspective

Improvement in Adherence to Surgical Antimicrobial Prophylaxis Guidelines after Implementation of a Multidisciplinary Quality Improvement Project

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