Surfactant-modified clinoptilolite as a salicylate carrier, salicylate kinetic release and its antibacterial activity

Natural Polymer/Inorganic Material Based Hybrid Scaffolds for Skin Wound Healing

“…These positively charged ions get attracted to the negatively charged cell membrane of bacteria. Oxidative damage takes places when these ions hit the proteins on the 154 In support to this, further investigations proved the bactericidal action of natural clinoptilolite modified with Cu C , Ag C , and benzalkonium ions were effective against Gram negative bacteria, Acinetobacter baumanii. 155 The bactericidal action of Quaternary ammonium compounds (QAC) incorporated zeolites A, X and Y were studied against Bacillus subtilis (B.subtilis).…”

Antibacterial activity of modified natural clinoptilolite against clinical isolates of Acinetobacter baumannii

“…However, the numbers of A. baumannii in the tubes with BCNZ were not higher than the corresponding control, suggesting that bacteria did not use BC as the source of carbon. Rapid decrease of bactericidal activity by decrease of BCNZ concentration and decrease of the antibacterial activity after 5 h of contact was also described for E. coli, while not for S. aureus [18].…”

“…The modified zeolites contained 20.33 mg Cu 2+ , 50.65 mg Ag + or 85.00 mg BC per gram of dry weight and denoted as CuNZ, AgNZ and BCNZ, respectively. The details of their characterization have been previously published [18,21]. The AgNZ and BCNZ were tested for antibacterial activity without previous sterilization in order to avoid the disintegration of loaded cations.…”

“…The BC at concentration of 850 mg L À1 and Cu at concentration of 260 mg L À1 resulted in 100% reduction of E. coli and S. aureus after 1 min and 24 h of contact, respectively [16,18]. The MBC values of BC against clinical isolates of Streptococcus agalactiae after 24 h of contact ranged between 0.70 and 12.50 mg L À1 [28].…”

“…We have previously reported the antibacterial activity of copper- [16] and surfactant-modified clinoptilolite [17,18] towards Acinetobacter junii, Escherichia coli and Staphylococcus aureus. Also, good antibacterial activity of silver-modified zeolite has been recently reported [19,20].…”