Surface Properties of Ti6Al7Nb Alloy: Surface Free Energy and Bacteria Adhesion

Krzywicka, Monika; Szymańska, Jolanta; Tofil, Szymon; Malm, Anna; Grzegorczyk, Agnieszka

doi:10.3390/jfb13010026

Cited by 7 publications

(6 citation statements)

References 43 publications

(59 reference statements)

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“…The high bacterial adhesion observed in anodized specimens is in accordance with the linear relationship between high SFE and the number of adherent bacteria reported in the literature [ 43 ]. Furthermore, it appears that marked hydrophobicity reduces bacterial adhesion [ 44 , 45 ], while up to now no dependence between bacterial adhesion and topographical characteristics has been found [ 46 , 47 ].…”

Section: Discussionsupporting

confidence: 89%

Bacterial and Cellular Response to Yellow-Shaded Surface Modifications for Dental Implant Abutments

et al. 2022

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Dental implants have dramatically changed the rehabilitation procedures in dental prostheses but are hindered by the possible onset of peri-implantitis. This paper aims to assess whether an anodization process applied to clinically used surfaces could enhance the adhesion of fibroblasts and reduce bacterial adhesion using as a reference the untreated machined surface. To this purpose, four different surfaces were prepared: (i) machined (MAC), (ii) machined and anodized (Y-MAC), (iii) anodized after sand-blasting and acid etching treatment (Y-SL), and (iv) anodized after double acid etching (Y-DM). All specimens were characterized by scanning electron microscopy (SEM) and energy-dispersive X-ray spectroscopy (EDX). Moreover, the mean contact angle in both water and diiodomethane as well as surface free energy calculation was assessed. To evaluate changes in terms of biological responses, we investigated the adhesion of Streptococcus sanguinis (S. sanguinis) and Enterococcus faecalis (E. faecalis), fetal bovine serum (FBS) adsorption, and the early response of fibroblasts in terms of cell adhesion and viability. We found that the anodization reduced bacterial adhesion, while roughened surfaces outperformed the machined ones for protein adsorption, fibroblast adhesion, and viability independently of the treatment. It can be concluded that surface modification techniques such as anodization are valuable options to enhance the performance of dental implants.

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Section: Discussionsupporting

confidence: 89%

Bacterial and Cellular Response to Yellow-Shaded Surface Modifications for Dental Implant Abutments

et al. 2022

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“…The modification of the physico-chemical properties [47,48] of the surface (e.g., surface charge, hydrophobicity, surface free energy), in the presence of CATASAN, could be responsible for the reduced microbial adhesion to a polystyrene surface. Although very initial data indicate that CATASAN could reduce the hydrophobicity of the polystyrene surface (Figure S2) and previous studies have demonstrated that surface hydrophobicity influences the initial binding of S. epidermidis [49], it is likely that the reduction of hydrophobicity is not the only reason of the reduction of cell adhesion.…”

Section: Discussionmentioning

confidence: 99%

CATASAN Is a New Anti-Biofilm Agent Produced by the Marine Antarctic Bacterium Psychrobacter sp. TAE2020

et al. 2022

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The development of new approaches to prevent microbial surface adhesion and biofilm formation is an emerging need following the growing understanding of the impact of biofilm-related infections on human health. Staphylococcus epidermidis, with its ability to form biofilm and colonize biomaterials, represents the most frequent causative agent involved in infections of medical devices. In the research of new anti-biofilm agents against S. epidermidis biofilm, Antarctic marine bacteria represent an untapped reservoir of biodiversity. In the present study, the attention was focused on Psychrobacter sp. TAE2020, an Antarctic marine bacterium that produces molecules able to impair the initial attachment of S. epidermidis strains to the polystyrene surface. The setup of suitable purification protocols allowed the identification by NMR spectroscopy and LC-MS/MS analysis of a protein–polysaccharide complex named CATASAN. This complex proved to be a very effective anti-biofilm agent. Indeed, it not only interferes with cell surface attachment, but also prevents biofilm formation and affects the mature biofilm matrix structure of S. epidermidis. Moreover, CATASAN is endowed with a good emulsification activity in a wide range of pH and temperature. Therefore, its use can be easily extended to different biotechnological applications.

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“…textured Ti-6Al-7Nb bio-alloy to correlate change in surface energy of the sample with microbial adhesion. 16 Thus, it is beyond doubt that judicious modification of the implant surface can be used as a means to successfully fine-tune its interaction mechanism with body and accelerate osseointegration.…”

Section: Introductionmentioning

confidence: 99%

“…Various macro/micro/nano topographies generated on Ti‐6Al‐4V and SS using ps‐laser are known to produce anti‐adhesive and antifouling surfaces with applications in food and medical industries 13,14 . Yu et al used laser to texture Ti‐6Al‐4V to promote cell adhesion, proliferation and growth of new blood vessels, 15 while Krzywicka et al textured Ti‐6Al‐7Nb bio‐alloy to correlate change in surface energy of the sample with microbial adhesion 16 . Thus, it is beyond doubt that judicious modification of the implant surface can be used as a means to successfully fine‐tune its interaction mechanism with body and accelerate osseointegration.…”

Section: Introductionmentioning

confidence: 99%

Picosecond laser‐induced hybrid groove structures on Ti‐6Al‐4V bio‐alloy to accelerate osseointegration

et al. 2023

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Regulating cell growth, extracellular matrix deposition and mineralization of artificial implants are some important parameters that decide the longevity of implants in the body. Picosecond laser-induced hybrid groove structures have been shown to improve these properties of the Ti-6Al-4V bio-alloy. Two hybrid structures containing groove patterns with periodic and non-periodic substructures therein were generated on Ti-6Al-4V by varying the extent of laser pulse overlapping on sample surface.Laser-induced alteration in surface topography, chemical composition and wettability of Ti-6Al-4V resulted in 3-fold increase in the rate of hydroxyapatite growth, 2.5-fold increment in protein adsorption and 2-fold enhancement in cell adhesion in comparison to pristine sample. While the periodic substructure was found to guide cell growth, the nonperiodic sub structure offered homogenous growth leading to higher overall cell density on the substrate surface.

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Surface Properties of Ti6Al7Nb Alloy: Surface Free Energy and Bacteria Adhesion

Cited by 7 publications

References 43 publications

Bacterial and Cellular Response to Yellow-Shaded Surface Modifications for Dental Implant Abutments

Bacterial and Cellular Response to Yellow-Shaded Surface Modifications for Dental Implant Abutments

CATASAN Is a New Anti-Biofilm Agent Produced by the Marine Antarctic Bacterium Psychrobacter sp. TAE2020

Picosecond laser‐induced hybrid groove structures on Ti‐6Al‐4V bio‐alloy to accelerate osseointegration

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