Surface plasmon resonance immuno assays – A perspective

Quantitative blood group typing using surface plasmon resonance

“…This is because detectors are often coupled with a microfluidic system with a diameter similar to the average cell size which ranges from 10 to15 mm. Therefore, most large cells are unsuited for use with microfluidic systems as cells are more likely to settle or congregate (Gutiérrez-Gallego et al, 2009). However, unlike most cells, RBCs are highly deformable in nature to allow for easy vascular transport, which bares similarities to microfluidics.…”

Biochemical markers of bone turnover in tibia fracture patients randomly assigned to growth hormone (GH) or placebo injections

“…As the ratio between the two pituitary-derived GH of 20 kDa and 22 kDa is rather constant in normal subjects, an altered ratio would be highly suggestive of administration of the 22 kDa recombinant GH [32]. This method is still being optimized [33] but the short time span required for a correct evaluation (within 24-36 h from GH injection) greatly limits this investigational tool and obviously the use of pituitary-derived GH, IGF-I, GH secretagogues, and gene doping will not be detected. However, the first athlete abusing GH was recently caught, using the isoform approach, in an unannounced out-of-competition test [34].…”

Trends and Perspectives in Immunosensors

“…The main types of direct optical immunosensor detectors are based on grating-couplers, Mach-Zehnder interferometers and SPR [78,79,80,81]. Some of the most sensitive optical immunosensors involve SPR, an optoelectronic phenomenon, first observed by Wood in 1902 [82].…”