Surface plasmon resonance biosensor based on grating disc with circular fluidic channel

Yih, Jenq Nan; Chiu, Kuo-Chi; Chou, Sheng-Yu; Lin, Chih‐Ming; Lan, Yung-Sung; Chen, Shu‐Jen; Cheng, Nai–Jen

doi:10.1109/nems.2011.6017420

Cited by 5 publications

(7 citation statements)

References 12 publications

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“…The preliminary results found by the authors of [ 34 ] showed SPR angle modification using a biomolecular layer on the CD-based biosensor structure. The authors of [ 35 ] presented an SPR-based CD biosensor with a circular fluidic channel. In the AFM test before 50 nm gold layer sputtering, the authors showed a grating groove depth of 64 nm and width of 468 nm.…”

Section: Swg and Nanograting-based Sensors Configurationsmentioning

confidence: 99%

“…Many other applications can be implemented using CDs-based structures, for example, SERS-based CDs have been described by the authors of [ 32 , 44 , 45 ]. Moreover, schematic, SEM, and AFM characterization of the CDs-based structures and the materials used to manufacture the different types of CDs have been described by the authors of [ 30 , 32 , 33 , 34 , 35 , 36 , 37 , 38 , 39 , 40 , 41 , 42 , 43 , 44 , 45 , 46 , 47 ], including the treatment methods made on the sample to prepare them for sensing applications. The main treatment method is exposure to metallic film.…”

Section: Swg and Nanograting-based Sensors Configurationsmentioning

confidence: 99%

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Resonant Subwavelength and Nano-Scale Grating Structures for Biosensing Application: A Comparative Study

Abutoama

Abuleil

Abdulhalim

2021

Sensors

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Resonant-based sensors are attractive optical structures due to the easy detection of shifts in the resonance location in response to variations in the analyte refractive index (RI) in comparison to non-resonant-based sensors. In particular, due to the rapid progress of nanostructures fabrication methods, the manufacturing of subwavelength and nano-scale gratings in a large area and at a low cost has become possible. A comparative study is presented involving analysis and experimental work on several subwavelength and nanograting structures, highlighting their nano-scale features’ high potential in biosensing applications, namely: (i) Thin dielectric grating on top of thin metal film (TDGTMF), which can support the excitation of extended surface plasmons (ESPs), guided mode resonance, or leaky mode; (ii) reflecting grating for conventional ESP resonance (ESPR) and cavity modes (CMs) excitation; (iii) thick dielectric resonant subwavelength grating exhibiting guided mode resonance (GMR) without a waveguide layer. Among the unique features, we highlight the following: (a) Self-referenced operation obtained using the TDGTMF geometry; (b) multimodal operation, including ESPR, CMs, and surface-enhanced spectroscopy using reflecting nanograting; (c) phase detection as a more sensitive approach in all cases, except the case of reflecting grating where phase detection is less sensitive than intensity or wavelength detection. Additionally, intensity and phase detection modes were experimentally demonstrated using off-the-shelf grating-based optical compact discs as a low-cost sensors available for use in a large area. Several flexible designs are proposed for sensing in the visible and infrared spectral ranges based on the mentioned geometries. In addition, enhanced penetration depth is also proposed for sensing large entities such as cells and bacteria using the TDGTMF geometry.

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Section: Swg and Nanograting-based Sensors Configurationsmentioning

confidence: 99%

Section: Swg and Nanograting-based Sensors Configurationsmentioning

confidence: 99%

Resonant Subwavelength and Nano-Scale Grating Structures for Biosensing Application: A Comparative Study

Abutoama

Abuleil

Abdulhalim

2021

Sensors

View full text Add to dashboard Cite

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“…SPR biosensing is based on changes in the refractive index very close to the sensor surface (usually gold or silver) caused when the analyte (in solution) binds to the biorecognition element immobilised on the sensor surface [165]. Grating-based [166] and prism-based [87] SPR approaches have been proposed. We have demonstrated an SPR-LoaD platform to simple multi-analyte immunoassay adaptable to detect specific diseases just by changing the capture antibody loaded onto the gold sensor [87].…”

Section: Optical Detectionmentioning

confidence: 99%

Advances in Microfluidics Technology for Diagnostics and Detection

2021

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Section: Amperometry/voltammetrymentioning

confidence: 99%

Biosensing on the Centrifugal Microfluidic Lab-on-a-Disc Platform

2020

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Lab-on-a-Disc (LoaD) biosensors are increasingly a promising solution for many biosensing applications. In the search for a perfect match between point-of-care (PoC) microfluidic devices and biosensors, the LoaD platform has the potential to be reliable, sensitive, low-cost, and easy-to-use. The present global pandemic draws attention to the importance of rapid sample-to-answer PoC devices for minimising manual intervention and sample manipulation, thus increasing the safety of the health professional while minimising the chances of sample contamination. A biosensor is defined by its ability to measure an analyte by converting a biological binding event to tangible analytical data. With evolving manufacturing processes for both LoaDs and biosensors, it is becoming more feasible to embed biosensors within the platform and/or to pair the microfluidic cartridges with low-cost detection systems. This review considers the basics of the centrifugal microfluidics and describes recent developments in common biosensing methods and novel technologies for fluidic control and automation. Finally, an overview of current devices on the market is provided. This review will guide scientists who want to initiate research in LoaD PoC devices as well as providing valuable reference material to researchers active in the field.

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Surface plasmon resonance biosensor based on grating disc with circular fluidic channel

Cited by 5 publications

References 12 publications

Resonant Subwavelength and Nano-Scale Grating Structures for Biosensing Application: A Comparative Study

Resonant Subwavelength and Nano-Scale Grating Structures for Biosensing Application: A Comparative Study

Advances in Microfluidics Technology for Diagnostics and Detection

Biosensing on the Centrifugal Microfluidic Lab-on-a-Disc Platform

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