Surface-modification of polystyrene-microtitre plates via grafting of glycidylmethacrylate and coating of poly-glycidylmethacrylate

Elimination and Prevention of Microbial Colonization of Central Venous Catheters Using Antibiotic Lock Technique and NonLeachable Form of Catheter Surface Incorporated Antibiotic by Gamma Radiation

“…The increase in grafting yield may be attributed to the increase in free radicals concentration that arises from the increase in the monomer concentration (Charlesby, 1960) and hence increase in the epoxy groups' content on polyurethane that act as surface linkers for the nucleophilic amino group of gentamicin. Other nucleophilic groups, as linkers, including NH2, OH, SH were reported by others (Eckert et al 2000 andNishiyama et al 2002). On the other hand, methanol facilitates the accessibility of GMA to the polymer active site; similar results were recorded by Inderjeet et al (1999) and El-Hag Ali et al (2008).…”

Covalent Immobilization of Glucose Oxidase on Well-Defined Polymer-Silicon Wafer Hybrids via Surface-Initiated Raft-Mediated Process

“…In this work, glycidyl methacrylate (GMA) was chosen because its corresponding polymer is wellknown potential linkers for biomolecules. 24,25,31 As shown in C 1s core-level spectra of the Si-PGMA surface (Fig. 3a), the presence of the grafted polymer on the silicon surface was ascertained by XPS analysis.…”

“…PGMA is a known surface linker and spacer for biomolecules. 24,25 Then GOD was covalently immobilized on the modified silicon surface through the ring-opening reaction between the amine groups of the GOD and the epoxide groups of the grafted GMA polymer chains. The composition of the modified silicon surface was characterized by X-ray photoelectron spectroscopy (XPS).…”

Polyacrylonitrile Fiber as Matrix for Immunodiagnostics

“…Covalent immobilization is difficult with the non-functionalized surfaces including PS. Eckert et al [Eckert, et al, 2000] have grafted glycidal methacrylate on PS microtiter plate for immobilizing proteins and have reported poor reproducibility of the results. Hence, modified and synthesized functional groups containing solid surfaces are being employed for ELISA.…”