Surface modification of plastic, glass and titanium by photoimmobilization of polyethylene glycol for antibiofouling

Ito, Yoshihiro; Hasuda, Hirokazu; Sakuragi, Makoto; Tsuzuki, Saki

doi:10.1016/j.actbio.2007.05.010

Cited by 77 publications

(77 citation statements)

References 42 publications

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“…10,11 Pure titanium was vacuum deposited on the plate by an electron beam of 400 nm (±25%) in width. The thickness of the titanium layer was controlled to maintain the transparency for optical microscopic observations.…”

Section: Materials and Methods Materialsmentioning

confidence: 99%

“…To biologically modify metal surfaces, silane-based coupling methods have been conventionally employed to prepare an initial organic layer on the metal surface. [7][8][9][10] However, in addition to physicochemical modification, [11][12][13] recent biomimetic approaches inspired by underwater organisms for surface modification have been proposed by many studies.…”

Section: Introductionmentioning

confidence: 99%

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Nanolayer formation on titanium by phosphonated gelatin for cell adhesion and growth enhancement

Zhou¹,

Park²,

Mao³

et al. 2015

IJN

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Phosphonated gelatin was prepared for surface modification of titanium to stimulate cell functions. The modified gelatin was synthesized by coupling with 3-aminopropylphosphonic acid using water-soluble carbodiimide and characterized by 31 P nuclear magnetic resonance and gel permeation chromatography. Circular dichroism revealed no differences in the conformations of unmodified and phosphonated gelatin. However, the gelation temperature was changed by the modification. Even a high concentration of modified gelatin did not form a gel at room temperature. Time-of-flight secondary ion mass spectrometry showed direct bonding between the phosphonated gelatin and the titanium surface after binding. The binding behavior of phosphonated gelatin on the titanium surface was quantitatively analyzed by a quartz crystal microbalance. Ellipsometry showed the formation of a several nanometer layer of gelatin on the surface. Contact angle measurement indicated that the modified titanium surface was hydrophobic. Enhancement of the attachment and spreading of MC-3T3L1 osteoblastic cells was observed on the phosphonated gelatin-modified titanium. These effects on cell adhesion also led to growth enhancement. Phosphonation of gelatin was effective for preparation of a cell-stimulating titanium surface.

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Section: Materials and Methods Materialsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Nanolayer formation on titanium by phosphonated gelatin for cell adhesion and growth enhancement

Zhou¹,

Park²,

Mao³

et al. 2015

IJN

Self Cite

View full text Add to dashboard Cite

show abstract

“…5,6 The repellency of hydrophobic surfaces is mainly ascribed to the lubricating gas films generated at the interface between the solid substrate and the liquid, which results in a shear-free liquid-air area and dramatically reduces the interaction at the solid-liquid interface. 7 For all the above mentioned applications, the robustness of a coating against complete wetting is crucial.…”

Section: Introductionmentioning

confidence: 99%

Manufacturing of mushroom-shaped structures and its hydrophobic robustness analysis based on energy minimization approach

et al. 2017

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The construction of stable hydrophobic surfaces has increasingly gained attention owing to its wide range of potential applications. However, these surfaces may become wet and lose their slip effect owing to insufficient hydrophobic stability. Pillars with a mushroom-shaped tip are believed to enhance hydrophobicity stability. This work presents a facile method of manufacturing mushroom-shaped structures, where, compared with the previously used method, the modulation of the cap thickness, cap diameter, and stem height of the structures is more convenient. The effects of the development time on the cap diameter and overhanging angle are investigated and well-defined mushroom-shaped structures are demonstrated. The effect of the microstructure geometry on the contact state of a droplet is predicted by taking an energy minimization approach and is experimentally validated with nonvolatile ultraviolet-curable polymer with a low surface tension by inspecting the profiles of liquid–vapor interface deformation and tracking the trace of the receding contact line after exposure to ultraviolet light. Theoretical and experimental results show that, compared with regular pillar arrays having a vertical sidewall, the mushroom-like structures can effectively enhance hydrophobic stability. The proposed manufacturing method will be useful for fabricating robust hydrophobic surfaces in a cost-effective and convenient manner.

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“…Another key is the immobilization or conjugation of bioactive molecules on gold nanoparticles for targeted drug delivery, molecular imaging, and in vitro diagnosis. To satisfy these key requirements, we developed a novel random copolymer composed of a "surface anchor part" (thiol group), 13,14,[18][19][20] "antibiofouling part" (PEG), 13,15,[21][22][23][24][25] and "bioreactivity part" (carboxyl group) for gold surface modification in particular.…”

mentioning

confidence: 99%

Synthesis of Novel Copolymer for Selective Biomolecule Immobilization on Gold Surface

Kim¹,

Lee²

2012

Bulletin of the Korean Chemical Society

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Surface modification of plastic, glass and titanium by photoimmobilization of polyethylene glycol for antibiofouling

Cited by 77 publications

References 42 publications

Nanolayer formation on titanium by phosphonated gelatin for cell adhesion and growth enhancement

Nanolayer formation on titanium by phosphonated gelatin for cell adhesion and growth enhancement

Manufacturing of mushroom-shaped structures and its hydrophobic robustness analysis based on energy minimization approach

Synthesis of Novel Copolymer for Selective Biomolecule Immobilization on Gold Surface

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