Surface interaction of ribonucleic acid constituents with spinel ferrite nanoparticles: a prebiotic chemistry experiment

Iqubal, Md. Asif; Sharma, Rachana; Kamaluddin, .

doi:10.1039/c6ra12247g

Cited by 17 publications

(11 citation statements)

References 40 publications

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“…Although several metal oxides have been used in previous oligomerization studies, to the best of our knowledge this important group of binary oxide minerals has not yet been tested. The experimental findings reported here, in relation to the latest use of spinel ferrite for the entrapment of ribonucleotides on its surface [ 46 , 47 ], further sheds light on the role of spinel ferrites during the prebiotic chemistry epoch.…”

Section: Introductionmentioning

confidence: 64%

Thermal Condensation of Glycine and Alanine on Metal Ferrite Surface: Primitive Peptide Bond Formation Scenario

Iqubal

Sharma

Jheeta³

et al. 2017

Life

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The amino acid condensation reaction on a heterogeneous mineral surface has been regarded as one of the important pathways for peptide bond formation. Keeping this in view, we have studied the oligomerization of the simple amino acids, glycine and alanine, on nickel ferrite (NiFe2O4), cobalt ferrite (CoFe2O4), copper ferrite (CuFe2O4), zinc ferrite (ZnFe2O4), and manganese ferrite (MnFe2O4) nanoparticles surfaces, in the temperature range from 50–120 °C for 1–35 days, without applying any wetting/drying cycles. Among the metal ferrites tested for their catalytic activity, NiFe2O4 produced the highest yield of products by oligomerizing glycine to the trimer level and alanine to the dimer level, whereas MnFe2O4 was the least efficient catalyst, producing the lowest yield of products, as well as shorter oligomers of amino acids under the same set of experimental conditions. It produced primarily diketopiperazine (Ala) with a trace amount of alanine dimer from alanine condensation, while glycine was oligomerized to the dimer level. The trend in product formation is in accordance with the surface area of the minerals used. A temperature as low as 50 °C can even favor peptide bond formation in the present study, which is important in the sense that the condensation process is highly feasible without any sort of localized heat that may originate from volcanoes or hydrothermal vents. However, at a high temperature of 120 °C, anhydrides of glycine and alanine formation are favored, while the optimum temperature for the highest yield of product formation was found to be 90 °C.

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Section: Introductionmentioning

confidence: 64%

Thermal Condensation of Glycine and Alanine on Metal Ferrite Surface: Primitive Peptide Bond Formation Scenario

Iqubal

Sharma

Jheeta³

et al. 2017

Life

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“…As the adsorbent pH pz is equal to 6.7, the surface charge of photocatalyst is positive and cationic at pH less than pH pz , and the adsorbent appears as anion with negative charge at pH higher than 6.7. Therefore, at acidic pHs (pH = 3), as the photocatalyst surface and the CIP molecule, both have a positive charge, the electrostatic repulsion is produced and the rate of degradation is reduced (45). The reason for the highest antibiotic stability in the acidic pH is the lack of the ionized carboxyl group (COOH) (46).…”

Section: Discussionmentioning

confidence: 99%

“…At pH 7, the adsorbent surface charge is negative and CIP has positive surface charge. The electrostatic attraction is then generated and the CIP molecule is transferred to the photocatalyst and causes further degradation of hydroxyl radicals (45). At basic pH (pH = 11), the photocatalyst and CIP molecule both have a negative charge, electrostatic repulsion is generated, and the CIP degradation is reduced (40).…”

Section: Discussionmentioning

confidence: 99%

“…HCl and NaOH solutions (0.1 N) were used for adjusting pH. The effects of different concentrations of antibiotics (3, 5, 7, and 9 mg/L), pHs (3, 7, and 11), amounts of photocatalysts (0.025, 0.05, 0.1, 0.2, 0.3, and 0.4 g), and irradiation times (15,30,45,60,75, and 90 minutes) were investigated in the presence of UV-C lamp on the antibiotic removal efficiency. During the research stages, the investigated parameters were optimized.…”

Section: Analysis and Characterization Of Nano-biomagnetic Cufe 2 O 4mentioning

confidence: 99%

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Magnetic nano-biocomposite CuFe2 O4 @methylcellulose (MC) prepared as a new nano-photocatalyst for degradation of ciprofloxacin from aqueous solution

Nasiri

Tamaddon

Mosslemin

et al. 2019

Environ Health Eng Manag

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Background: Antibiotics such as ciprofloxacin (CIP) are even more important in bacterial resistance, even at low concentrations. The aim of this research was to synthesize CuFe2 O4 @methylcellulose (MC) as a new nano-photocatalyst for degradation of CIP from aqueous solution. Methods: The nano-photocatalyst (CuFe2 O4 @MC) was characterized by FESEM, energy dispersive spectroscopy (EDS), X-ray diffraction (XRD) and Fourier transform infrared (FTIR), thermogravimetric analysis (TGA), and vibrating sample magnetometer (VSM). Powder XRD and EDS analysis confirmed the formation of pure-phase spinel ferrites. After CuFe2 O4 @MC characterization, the effective parameters in removal efficiency of CIP such as reaction time, initial antibiotic concentration, pH, photocatalyst loading, and degradation kinetic were investigated and conditions were optimized. Then, CIP degradation experiments were conducted on the real sample in the optimal conditions. The removal of chemical oxygen demand (COD) was determined under optimum conditions. Results: The structural characterization of the magnetic nanobiocomposite showed that it is in nanoscale, ferromagnetic property, and thermal stability. The optimal conditions were obtained at pH = 7, irradiation time (90 minutes), photocatalyst loading (0.2 g), and initial concentration of CIP (3 mg/L). The removal efficiency of CIP in the optimal conditions was obtained as 80.74% and 72.87% from the synthetic and real samples, respectively. The removal of COD was obtained as 68.26% in this process. The evaluation of kinetic linear models showed that the photocatalytic degradation process was fitted by pseudo-first order kinetic model and Langmuir-Hinshelwood. CuFe2 O4 @MC photocatalyst had a good stability and reusability for the fourth runs. Conclusion: The photocatalytic degradation of CIP from aqueous media with CuFe2 O4 @MC photocatalyst has a high efficiency, which can be used in the treatment of pharmaceutical wastewaters.

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“…According to Iqubal and co-workers, spinel metal ferrites might have played an important role in the context of prebiotic chemistry and the origin of life by concentrating and further condensing the important “bio-monomers” in the primeval soup. The latest studies involving spinel metal ferrite and ribonucleotides result in their oligomerization [ 41 , 42 ], shedding light on the importance of spinel metal ferrites during the prebiotic chemistry epoch.…”

Section: Metabolism Firstmentioning

confidence: 99%

The Landscape of the Emergence of Life

Jheeta¹

2017

Life

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This paper reports on the various nuances of the origins of life on Earth and highlights the latest findings in that arena as reported at the Network of Researchers on Horizontal Gene Transfer and the Last Universal Common Ancestor (NoR HGT and LUCA) which was held from the 3–4th November 2016 at the Open University, UK. Although the answers to the question of the origin of life on Earth will not be fathomable anytime soon, a wide variety of subject matter was able to be covered, ranging from examining what constitutes a LUCA, looking at viral connections and “from RNA to DNA”, i.e., could DNA have been formed simultaneously with RNA, rather than RNA first and then describing the emergence of DNA from RNA. Also discussed are proteins and the origins of genomes as well as various ideas that purport to explain the origin of life here on Earth and potentially further afield elsewhere on other planets.

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Surface interaction of ribonucleic acid constituents with spinel ferrite nanoparticles: a prebiotic chemistry experiment

Abstract: A prebiotic chemistry experiment involving interaction between ribonucleotides and spinel ferrite nanoparticles has been carried out.

Cited by 17 publications

References 40 publications

Thermal Condensation of Glycine and Alanine on Metal Ferrite Surface: Primitive Peptide Bond Formation Scenario

Thermal Condensation of Glycine and Alanine on Metal Ferrite Surface: Primitive Peptide Bond Formation Scenario

Magnetic nano-biocomposite CuFe2 O4 @methylcellulose (MC) prepared as a new nano-photocatalyst for degradation of ciprofloxacin from aqueous solution

The Landscape of the Emergence of Life

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