Surface functionalization of poly(lactic acid) film by UV‐photografting of N‐vinylpyrrolidone

Abstract

The photoinitiated grafting of N-vinylpyrrolidone (NVP) onto poly(lactic acid) (PLA) film with the use of benzophenone (BP) as the initiator, modified the natural hydrophobic PLA behavior to an hydrophilic film with desirable wettability. The surface photografting parameters-percent conversion of monomer to overall photopolymerization (Cp), percent conversion of monomer to the photograft polymerization (Cg), and grafting efficiency (Eg) were calculated. The resulting film surface was analyzed using ATR-FTIR and UV spectroscopy, derivative spectroscopy and water contact angle. Besides, we demonstrated that the grafted polyvinylpyrrolidone chains could easily react with iodine to form a complex as the homopolymer does with antibacterial activity.

Polylactic acid (PLA) synthesis and modifications: a review

“…N-vinylpyrrolidone (NVP) has seldom been used in surface photografting, although some researchers have used X-ray or other initiation methods to graft it onto different substrates [27].…”

“…Laminin-modified chitosan membrane significantly increases SCs attachment and affinity for directing peripheral nerve regeneration [26]. Gutierrez-Villarreal et al also chose the photoinduced grafting process to modify PLA for its low operation cost, weak penetration of absorbed UV light, and the required mild reaction conditions that do not affect the bulk polymer [27].…”

Surface modification of biomaterials by photochemical immobilization and photograft polymerization to improve hemocompatibility

“…Under the irradiation of UV, the purpose of improving surface properties can be realized via free radical surfacephotografting polymerization of functional unsaturated monomers. Monomers used in photografting polymerization are generally 2-hydroxyethyl methacrylate (HEMA) [12], glycidyl methacrylate (GMA) [13], N-vinylpyrrolidone (NVP) [14], 2-methacryloyloxyethyl phosphorylcholine (MPC) [15], N,N-dimethylaminoethyl methacrylate (DMAEMA) [16], 3-dimethyl(methacryloyloxyethyl) ammonium propane sulfonate (DMAPS), polyethylene glycol methacrylate (PEGMA) [17] (Fig. 3), etc.…”

Development and Characterization of Photoinduced Acrylamide-Grafted Polylactide Films for Biomedical Applications

“…These covalent grafting processes are very attractive as new desirable functional of different types can be introduced onto the polymer surfaces to change surface morphology, adhesiveness, and biocompatibility. For PLA, some research has been conducted on surface grafting with different materials [13,14].…”