Surface-Enhanced Absorption Spectroscopy for Optical Fiber Sensing

Abstract

Visible and near-infrared spectroscopy are widely used for sensing applications but suffer from poor signal-to-noise ratios for the detection of compounds with low concentrations. Enhancement by surface plasmon resonance is a popular technique that can be utilized to increase the signal of absorption spectroscopy due to the increased near-field created close to the plasmons. Despite interest in surface-enhanced infrared absorption spectroscopy (SEIRAS), the method is usually applied in lab setups rather than real-life sensing situations. This study aimed to achieve enhanced absorption from plasmons on a fiber-optic probe and thus move closer to applications of SEIRAS. A tapered coreless fiber coated with a 100 nm Au film supported signal enhancement at visible wavelengths. An increase in absorption was shown for two dyes spanning concentrations from 5 × 10−8 mol/L to 8 × 10−4 mol/L: Rhodamine 6G and Crystal Violet. In the presence of the Au film, the absorbance signal was 2–3 times higher than from an identically tapered uncoated fiber. The results confirm that the concept of SEIRAS can be implemented on an optical fiber probe, enabling enhanced signal detection in remote sensing applications.

Is the Use of Surface-Enhanced Infrared Spectroscopy Justified in the Selection of Peptide Fragments That Play a Role in Substrate–Receptor Interactions? Adsorption of Amino Acids and Neurotransmitters on Colloidal Ag and Au Nanoparticles

“…The supplemented information in the databases on spectroscopy of amino acids and neurotransmitters will also allow a more accurate interpretation of the spectra of complex molecules, such as peptides and proteins. This is because many research groups have focused on the preparation of new substrates and the determination of signal enhancement and SEIRA mechanism using adsorbates, which usually contain carbonyl and thiol groups or adsorbates in the form of small and/or symmetric molecules ,,,,,− and less frequently thin polymer films. − Few literature reports indicate the use of SEIRA in the study of biosensors, − in cancer drug research (cis-platinum and doxorubicin), and as a diagnostic criterion for cancer. , …”