Surface engineering of additively manufactured titanium alloys for enhanced clinical performance of biomedical implants: A review of recent developments

Muthaiah, V.M. Suntharavel; Indrakumar, Sushma; Suwas, Satyam; Chatterjee, Kaushik

doi:10.1016/j.bprint.2021.e00180

Cited by 46 publications

(20 citation statements)

References 115 publications

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“…Roughening dental implant surfaces can be done by various methods ( Shayganpour et al., 2015 ; Muthaiah et al., 2022 ). Roughness sizes vary depending on the surface treatment.…”

Section: Surface Modification Of Ti Implantsmentioning

confidence: 99%

RETRACTED: Titanium and titanium alloys in dentistry: Current trends, recent developments, and future prospects

Hoque¹,

Showva²,

Ahmed³

et al. 2022

Heliyon

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“…Roughening dental implant surfaces can be done by various methods ( Shayganpour et al., 2015 ; Muthaiah et al., 2022 ). Roughness sizes vary depending on the surface treatment.…”

Section: Surface Modification Of Ti Implantsmentioning

confidence: 99%

RETRACTED: Titanium and titanium alloys in dentistry: Current trends, recent developments, and future prospects

Hoque¹,

Showva²,

Ahmed³

et al. 2022

Heliyon

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“…These implanted scaffolds are translational therapeutic approaches [5] using tissue engineering techniques [6] to treat degenerative diseases [7] and improve cartilage regeneration efficiency [8] for osteoarthritis patients. At present, titanium filler [9] is still the most commonly used in metallic scaffolds [10] in advanced combinations with polymer-based biomaterials [11][12][13] during the green composite fabrication processes [14]. However, the existing titanium dioxide filler in these applications [15] was over-strengthened or too hard, resulting in a thin oxide surface layer not being discussed [16].…”

Section: Introductionmentioning

confidence: 99%

Structural Characterization Analyses of Low Brass Filler Biomaterial for Hard Tissue Implanted Scaffold Applications

et al. 2022

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A biomaterial was created for hard tissue implanted scaffolds as a translational therapeutic approach. The existing biomaterials containing titanium dioxide filler posed a risk of oxygen gas vacancy. This will block the canaliculars, leading to a limit on the nutrient fluid supply. To overcome this problem, low brass was used as an alternative filler to eliminate the gas vacancy. Low brass with composition percentages of 0%, 2%, 5%, 15%, and 30% was filled into the polyester urethane liquidusing the metallic filler polymer reinforced method. The structural characterizations of the low brass filler biomaterial were investigated by Field Emission Scanning Electron Microscopy. The results showed the surface membrane strength was higher than the side and cross-section. The composition shapes found were hexagon for polyester urethane and peanut for low brass. Low brass stabilised polyester urethane in biomaterials by the formation of two 5-ringed tetrahedral crystal structures. The average pore diameter was 308.9 nm, which is suitable for articular cartilage cells. The pore distribution was quite dispersed, and its curve had a linear relationship between area and diameter, suggestive of the sphere-shaped pores. The average porosities were different between using FESEM results of 6.04% and the calculated result of 3.28%. In conclusion, this biomaterial had a higher surface membrane strength and rather homogeneous dispersed pore structures.

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“…Notably, in earlier work with conventionally manufactured alloys, the surfaces were initially smoothened to low roughness prior to the EPD of nanoHAp. , However, we successfully prepared these coatings even on surfaces of the additively manufactured parts with markedly higher roughness. Surface engineering of additively manufactured metallic implants and specifically for titanium implants is an active area fo research . These results will enable the fabrication of orthopedic implants of complex geometry, leveraging the opportunities of additive manufacturing, and their clinical performance can be augmented by coating with nanoHAp prepared by EPD.…”

Section: Resultsmentioning

confidence: 99%

Electrophoretic Deposition of Nanocrystalline Calcium Phosphate Coating for Augmenting Bioactivity of Additively Manufactured Ti-6Al-4V

et al. 2021

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Additive manufacturing (AM) is being widely explored for engineering biomedical implants. The microstructure and surface finish of additively manufactured parts are typically different from wrought parts and exhibit limited bioactivity despite the other advantages of using AM for fabrication. The aim of this study was to enhance the bioactivity of selective laser melted Ti-6Al-4V alloy by electrophoretic deposition of nanohydroxyapatite (nanoHAp) coatings. The deposition parameters were systematically investigated after the coatings were deposited on the as-manufactured surface or after polishing the surface of the additively-manufactured sample. The surfaces were coated with nanoHAp suspended in either ethanol or butanol using different voltages (10, 30, or 50 V) for varied deposition times. The formation of the nanoHAp coating was confirmed by Fourier-transform infrared spectroscopy and X-ray diffraction. Microstructural analysis revealed that several conditions of the coating led to crack formation. The coated samples were subsequently heat-treated to improve the integrity of the coating. Heat treatment led to crack formation in several conditions due to thermal shrinkages. Coatings prepared using butanol were more uniform and had minimal cracks compared with the use of ethanol. Nanoindentation confirmed good stability and integrity of the nanoHAP coatings on the as-manufactured and polished surfaces. The coating on the as-manufactured sample exhibited higher hardness and lower elastic modulus as compared with the coating on the polished sample. In vitro study revealed that the nanoHAp coating markedly enhanced the attachment, proliferation, and differentiation of preosteoblasts on the alloy. These results provide a viable route to enhancing the bioactivity through deposition of nanoHAp with important implications for engineering additively manufactured orthopedic and dental implants suitable for better clinical performance.

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Surface engineering of additively manufactured titanium alloys for enhanced clinical performance of biomedical implants: A review of recent developments

Cited by 46 publications

References 115 publications

RETRACTED: Titanium and titanium alloys in dentistry: Current trends, recent developments, and future prospects

RETRACTED: Titanium and titanium alloys in dentistry: Current trends, recent developments, and future prospects

Structural Characterization Analyses of Low Brass Filler Biomaterial for Hard Tissue Implanted Scaffold Applications

Electrophoretic Deposition of Nanocrystalline Calcium Phosphate Coating for Augmenting Bioactivity of Additively Manufactured Ti-6Al-4V

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