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2022
DOI: 10.1016/j.mtbio.2022.100380
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Surface configuration of microarc oxidized Ti with regionally loaded chitosan hydrogel containing ciprofloxacin for improving biological performance

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Cited by 8 publications
(6 citation statements)
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“…At present, research on adhesive materials in the drug delivery phase mainly aims at precise targeting and dosing, and low toxicity in order to achieve the best therapeutic effect. 109 Adhesive materials can provide space and time control for the release of various therapeutic drugs, including small-molecule and macromolecule drugs, and cells. 35,39 Adhesive materials have the characteristics of adjustable physical properties, controllable degradability to protect unstable drugs from degradation, 110 and the use of a platform for various physical chemistry interactions between the adhesive material and encapsulated drug, which can also reduce the administration frequency for convenient medication.…”
Section: Drug Deliverymentioning
confidence: 99%
“…At present, research on adhesive materials in the drug delivery phase mainly aims at precise targeting and dosing, and low toxicity in order to achieve the best therapeutic effect. 109 Adhesive materials can provide space and time control for the release of various therapeutic drugs, including small-molecule and macromolecule drugs, and cells. 35,39 Adhesive materials have the characteristics of adjustable physical properties, controllable degradability to protect unstable drugs from degradation, 110 and the use of a platform for various physical chemistry interactions between the adhesive material and encapsulated drug, which can also reduce the administration frequency for convenient medication.…”
Section: Drug Deliverymentioning
confidence: 99%
“…Incorporating drugs, such as antibiotics, is an effective means of rapid sterilization during early implantation stages. For example, Zhou et al [154] used ciprofloxacin-loaded CS hydrogel to modify the coating, effectively sterilizing the sample with the bacteriostatic zone. Xu et al [155] covalently grafted vancomycin to the MAO coating, creating Ti-@MV with significant antibacterial properties and enhanced osteogenic differentiation of BMSCs.…”
Section: Antibacterialmentioning
confidence: 99%
“…A Cell Counting Kit-8 (CCK8) assay was used to test the cell viability of (COL/PS) 4 @CaCO 3 using mouse fibroblast (L929) cells. 39 The subcutaneous implantation model, which has been previously reported, 40 was used to evaluate the in vivo degrading property and host response of (COL/PS) 4 @CaCO 3 .…”
Section: Study Of Hemocompatibility Cytocompatibility and Biodegradab...mentioning
confidence: 99%