In order to research the influence of friction conditions on the sheet metal deformation behavior under the fluid pressure, the experimental method that can test the relationship between fluid pressure and wall thickness was proposed in this paper. The theoretical model about the quantitative variation relationship between fluid pressure and wall thickness together with the theoretical model about the quantitative variation relationship between friction coefficient and wall thickness, was obtained by theoretical derivation. At the same time, it could be concluded that friction contact region close to the tensile end was easier to satisfy the plastic yield criterion. Therefore, the plastic deformation initially occurred at this area and fracture emerged on account of excessive reduction of the sheet thickness. Simulation analysis with 304 stainless steel was carried out. The result indicated that the capacity of sheet uniform deformation decreased with the increasing of the friction coefficient. When the friction coefficient increased from 0.08 to 0.20, the uniform elongation decreased by 32%. But when other conditions were kept unchanged, the greater the fluid pressure was, the thinner the sheet would be. Experiments indicated that the necking and fracture appeared in the gauge length near the tensile end with different lubricants. And these provided a theoretical basis for the process and device design of sheet metal hydroforming.