Surface active ionic liquid and Tween-80 blend as an effective dispersant for crude oil spill remediation

Nazar, Mudassar; Shah, Mansoor Ul Hassan; Yahya, Wan Zaireen Nisa; Goto, Masahiro; Moniruzzaman, Muhammad

doi:10.1016/j.eti.2021.101868

Cited by 17 publications

(26 citation statements)

References 44 publications

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“…The SLNs were prepared using stearic acid as the physiological lipid that is widely available, is relatively cheap, and dissolves soluble flurbiprofen . Tween 80 was added as an emulsifier due to its HLB value, surface tension-reducing properties, stearic ability, nonionic nature, and improved permeation enhancement attribute . The particle size determined using photon correlation spectroscopy for the optimized SLN formulation (F5) was larger as compared to their SEM results (Table and Figure ).…”

Section: Resultsmentioning

confidence: 99%

Optimization of Chitosan-Decorated Solid Lipid Nanoparticles for Improved Flurbiprofen Transdermal Delivery

et al. 2023

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Transdermal delivery is a potential alternative route to oral administration for drugs associated with stomach discomfort, such as flurbiprofen, a widely nonsteroidal anti-inflammatory drug (NSAID). This study aimed to design solid lipid nanoparticle (SLN) transdermal formulations of flurbiprofen. Chitosan-coated SLNs were prepared by the solvent emulsification method, and their properties and permeation profiles across the excised rat skin were characterized. The particle size of uncoated SLNs was at 695 ± 4.65 nm, which increased to 714 ± 6.13, 847 ± 5.38, and 900 ± 8.65 nm upon coating with 0.05, 0.10, and 0.20% of chitosan, respectively. The drug association efficiency was improved when a higher concentration of chitosan was employed over SLN droplets that endowed a higher affinity of flurbiprofen with chitosan. The drug release was significantly retarded as compared to the uncoated entities and followed non-Fickian anomalous diffusion that was depicted by "n" values of >0.5 and <1. Also, the total permeation of chitosan-coated SLNs (F7−F9) was significantly higher than that of the noncoated formulation (F5). Overall, this study has successfully designed a suitable carrier system of chitosan-coated SLNs that provide insight into the current conventional therapeutic approaches and suggest new directions for the advancements in transdermal drug delivery systems for improved permeation of flurbiprofen.

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Section: Resultsmentioning

confidence: 99%

Optimization of Chitosan-Decorated Solid Lipid Nanoparticles for Improved Flurbiprofen Transdermal Delivery

et al. 2023

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“…This ratio was selected because it gave the highest effectiveness in our previous study. 14 The total surfactant mass fraction was 5%.…”

Section: Methodsmentioning

confidence: 99%

“…A 60:40 (w/w) mixture of Tween-80 and [Bmim][Lausar] was prepared in water. This ratio was selected because it gave the highest effectiveness in our previous study . The total surfactant mass fraction was 5%.…”

Section: Methodsmentioning

confidence: 99%

“…The resulting aggregation behavior and crude oil dispersion were impressive, and the newly developed formulation effectively dispersed the Arab crude oil at a rate of 81.19%. 14 The toxicity and biodegradability of this dispersant need to be evaluated to ensure its safe utilization in the marine environment. 15 , 16 To prevent irreversible harm and disturbance of the natural ecosystem, the applied dispersant must be biodegradable.…”

Section: Introductionmentioning

confidence: 99%

“…Recently, we formulated a novel environmentally benign dispersant for oil spill remediation by mixing the food-based surfactant Tween-80 with the SAIL 1-butyl-3-methylimidazolium lauroyl sarcosinate [Bmim][Lausar]. The resulting aggregation behavior and crude oil dispersion were impressive, and the newly developed formulation effectively dispersed the Arab crude oil at a rate of 81.19% . The toxicity and biodegradability of this dispersant need to be evaluated to ensure its safe utilization in the marine environment. , To prevent irreversible harm and disturbance of the natural ecosystem, the applied dispersant must be biodegradable. , Alicyclic SAILs containing morpholinium and piperidinium cations have shown 100% biodegradation after 28 days of testing .…”

Section: Introductionmentioning

confidence: 99%

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Ionic Liquid and Tween-80 Mixture as an Effective Dispersant for Oil Spills: Toxicity, Biodegradability, and Optimization

et al. 2022

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Chemical dispersants are used extensively for oil spill remediation. Most of these dispersants are composed of a mixture of surfactants and organic solvents, which raises concerns about aquatic toxicity and environmental impact. In this study, the toxicity and biodegradability of an oil spill dispersant composed of the surface-active ionic liquid 1-butyl-3-methylimidazolium lauroyl sarcosinate [Bmim][Lausar] and Tween-80 were investigated. In addition, important environmental factors including salinity, temperature, and wave-mixing energy were optimized to obtain maximum dispersion effectiveness. The acute toxicity against zebrafish ( Danio rerio ) showed that the developed dispersant was practically non-toxic with a median lethal dose of more than 100 mg L –1 after 96 h. The dispersant also demonstrated outstanding biodegradability of 66% after 28 days. A model was developed using a response surface methodology that efficiently ( R 2 = 0.992) related the salinity, temperature, and wave-mixing energy of seawater to dispersion effectiveness. The system was then optimized, and a high dispersion effectiveness of 89.70% was obtained with an experimental error of less than 2%. Our findings suggest that the surface-active ionic liquid and Tween-80 mixture could be a viable alternative to toxic chemical dispersants for oil spill remediation.

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Enhanced remediation of hydrocarbons contaminated soil using electrokinetic soil flushing – Landfarming processes

Effendi

Ramadan

Helmy

2022

Bioresource Technology Reports

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Surface active ionic liquid and Tween-80 blend as an effective dispersant for crude oil spill remediation

Cited by 17 publications

References 44 publications

Optimization of Chitosan-Decorated Solid Lipid Nanoparticles for Improved Flurbiprofen Transdermal Delivery

Optimization of Chitosan-Decorated Solid Lipid Nanoparticles for Improved Flurbiprofen Transdermal Delivery

Ionic Liquid and Tween-80 Mixture as an Effective Dispersant for Oil Spills: Toxicity, Biodegradability, and Optimization

Enhanced remediation of hydrocarbons contaminated soil using electrokinetic soil flushing – Landfarming processes

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