Surface Acoustic Wave Driven Microfluidics – A Review

Luong, Trung-Dung; Nguyen, Nam Trung

doi:10.2174/1876402911002030217

Cited by 70 publications

(19 citation statements)

References 48 publications

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“…Furthermore, this phenomenon of streaming-induced acoustic traps have led to the development of digital acoustofluidic devices whereby a carrier droplet can be manoeuvered in a 2-D grid driven by hydrodynamic acoustic traps [48,51]. A variety of SAW-I tweezers for droplet manipulation has been discussed elsewhere [20].…”

Section: (I) Bulk Acoustic Manipulationmentioning

confidence: 99%

“…Such technologies are classified here as active actuation techniques. A gamut of previous literature surveys provide a comprehensive assessment of acoustic tweezers based on BAW [10,12], SAW [8,9,20] or both [1,5]. However, a few reports address acoustically actuated autonomous agents and are typically limited to only a single type of agent [15,21].…”

Section: Introductionmentioning

confidence: 99%

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Contactless acoustic micro/nano manipulation: a paradigm for next generation applications in life sciences

2020

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Acoustic actuation techniques offer a promising tool for contactless manipulation of both synthetic and biological micro/nano agents that encompass different length scales. The traditional usage of sound waves has steadily progressed from mid-air manipulation of salt grains to sophisticated techniques that employ nanoparticle flow in microfluidic networks. State-of-the-art in microfabrication and instrumentation have further expanded the outreach of these actuation techniques to autonomous propulsion of micro-agents. In this review article, we provide a universal perspective of the known acoustic micromanipulation technologies in terms of their applications and governing physics. Hereby, we survey these technologies and classify them with regards to passive and active manipulation of agents. These manipulation methods account for both intelligent devices adept at dexterous non-contact handling of micro-agents, and acoustically induced mechanisms for self-propulsion of micro-robots. Moreover, owing to the clinical compliance of ultrasound, we provide future considerations of acoustic manipulation techniques to be fruitfully employed in biological applications that range from label-free drug testing to minimally invasive clinical interventions.

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Section: (I) Bulk Acoustic Manipulationmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Contactless acoustic micro/nano manipulation: a paradigm for next generation applications in life sciences

2020

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“…Moreover, SAW devices are largely employed in telecommunications with more than three billion SAW components manufactured every year and used as band pass filters and resonators in radio receivers of mobile cell phones, base stations, and RF front ends [7][8][9][10][11][12][13]. Finally, they are employed in many other different areas, such as automotive [14] and bioengineering applications, where they are used, for instance, as microfluidic devices [15][16][17] by exploiting the fact that, by inducing an electric field and generating a mechanical wave, it is possible to pump and drive liquids. The main advantages of SAW-based sensors as opposed to other kinds of sensors are their low cost, small size, high-temperature stability, and the possibility to be used as wireless passive sensors [18].…”

Section: Introductionmentioning

confidence: 99%

On the Performance Evaluation of Commercial SAW Resonators by Means of a Direct and Reliable Equivalent-Circuit Extraction

et al. 2021

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Nowadays, surface acoustic wave (SAW) resonators are attracting growing attention, owing to their widespread applications in various engineering fields, such as electronic, telecommunication, automotive, chemical, and biomedical engineering. A thorough assessment of SAW performance is a key task for bridging the gap between commercial SAW devices and practical applications. To contribute to the accomplishment of this crucial task, the present paper reports the findings of a new comparative study that is based on the performance evaluation of different commercial SAW resonators by using scattering (S-) parameter measurements coupled with a Lorentzian fitting and an accurate modelling technique for the straightforward extraction of a lumped-element equivalent-circuit representation. The developed investigation thus provides ease and reliability when choosing the appropriate commercial device, depending on the requirements and constraints of the given sensing application. This paper deals with the performance evaluation of commercial surface acoustic wave (SAW) resonators by means of scattering (S-) parameter measurements and an equivalent-circuit model extracted using a reliable modeling procedure. The studied devices are four TO-39 packaged two-port resonators with different nominal operating frequencies: 418.05, 423.22, 433.92, and 915 MHz. The S-parameter characterization was performed locally around the resonant frequencies of the tested SAW resonators by using an 8753ES Agilent vector network analyzer (VNA) and a home-made calibration kit. The reported measurement-based study has allowed for the development of a comprehensive and detailed comparative analysis of the performance of the investigated SAW devices. The characterization and modelling procedures are fully automated with a user-friendly graphical user interface (GUI) developed in the Python environment, thereby making the experimental analysis faster and more efficient.

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“…A miniaturised reactor also allows for more precise control over reaction parameters, as well as the safer handling of hazardous or exothermic reactions [3][4][5][6]. Owing to these advantages and the development of microfluidic devices [7][8][9], microreactors-particularly, microfluidic reactors-have attracted enormous research interests [10][11][12][13][14]. Nevertheless, these microreactors face difficulties in handling minute amounts of reactants.…”

Section: Introductionmentioning

confidence: 99%

Liquid Marbles as Miniature Reactors for Chemical and Biological Applications

et al. 2020

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The need for miniaturised reaction systems has led to the development of various microreactor platforms, such as droplet-based microreactors. However, these microreactors possess inherent drawbacks, such as rapid evaporation and difficult handling, that limit their use in practical applications. Liquid marbles are droplets covered with hydrophobic particles and are a potential platform that can overcome the weaknesses of bare droplets. The coating particles completely isolate the interior liquids from the surrounding environment, thus conveniently encapsulating the reactions. Great efforts have been made over the past decade to demonstrate the feasibility of liquid marble-based microreactors for chemical and biological applications. This review systemically summarises state-of-the-art implementations of liquid marbles as microreactors. This paper also discusses the various aspects of liquid marble-based microreactors, such as the formation, manipulation, and future perspectives.

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Surface Acoustic Wave Driven Microfluidics – A Review

Cited by 70 publications

References 48 publications

Contactless acoustic micro/nano manipulation: a paradigm for next generation applications in life sciences

Contactless acoustic micro/nano manipulation: a paradigm for next generation applications in life sciences

On the Performance Evaluation of Commercial SAW Resonators by Means of a Direct and Reliable Equivalent-Circuit Extraction

Liquid Marbles as Miniature Reactors for Chemical and Biological Applications

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