Suprasellar Mature Cystic Teratoma: An Unusual Location for an Uncommon Tumor

Sweiss, Raed; Shweikeh, Faris; Sweiss, Fadi; Zyck, Stephanie; Dalvin, Lauren A; Siddiqi, Javed

doi:10.1155/2013/180497

Cited by 12 publications

(11 citation statements)

References 16 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…They can be further classified as mature, immature, or malignant [8]. Mature teratomas are well-differentiated, generally benign masses possessing locally aggressive behavior (adhesion to/displacement of adjacent structures) [9]. Head and neck sites are rare and represent only 2% of all teratomas [5].…”

Section: Discussionmentioning

confidence: 99%

“…CT and MRI imaging are essential to determine lesion characteristics, such as the presence of mixed density tissues such as fat, muscle, bone, soft tissue, and cartilage. Suprasellar teratomas can be particularly challenging as the pituitary infundibulum can appear convoluted or elongated from local mass effect [9]. Such lesions that involve the skull base have been previously removed using an endoscopic endonasal approach [10].…”

Section: Discussionmentioning

confidence: 99%

“…Benign, mature teratomas have been reported to have survival rates over 90% after 10 years [9]. However, tumor recurrence has been reported through a phenomenon known as “growing teratoma syndrome,” which is extremely rare and refers to a relapse of malignancy due to partial response to surgical resection or chemotherapy [18].…”

Section: Discussionmentioning

confidence: 99%

See 2 more Smart Citations

Endoscopic Resection of Skull Base Teratoma in Klippel-Feil Syndrome through Use of Combined Ultrasonic and Bipolar Diathermy Platforms

Edward

Psaltis

Williams

et al. 2017

Case Reports in Otolaryngology

View full text Add to dashboard Cite

Klippel-Feil syndrome (KFS) is associated with numerous craniofacial abnormalities but rarely with skull base tumor formation. We report an unusual and dramatic case of a symptomatic, mature skull base teratoma in an adult patient with KFS, with extension through the basisphenoid to obstruct the nasopharynx. This benign lesion was associated with midline palatal and cerebral defects, most notably pituitary and vertebrobasilar arteriolar duplications. A multidisciplinary workup and a complete endoscopic, transnasal surgical approach between otolaryngology and neurosurgery were undertaken. Out of concern for vascular control of the fibrofatty dense tumor stalk at the skull base and need for complete teratoma resection, we successfully employed a tissue resection tool with combined ultrasonic and bipolar diathermy to the tumor pedicle at the sphenoid/clivus junction. No CSF leak or major hemorrhage was noted using this endonasal approach, and no concerning postoperative sequelae were encountered. The patient continues to do well now 3 years after tumor extirpation, with resolution of all preoperative symptoms and absence of teratoma recurrence. KFS, teratoma biology, endocrine gland duplication, and the complex considerations required for successfully addressing this type of advanced skull base pathology are all reviewed herein.

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Endoscopic Resection of Skull Base Teratoma in Klippel-Feil Syndrome through Use of Combined Ultrasonic and Bipolar Diathermy Platforms

Edward

Psaltis

Williams

et al. 2017

Case Reports in Otolaryngology

View full text Add to dashboard Cite

show abstract

“…Spinal teratoma is included in the category of extragonadal teratomas arising within the neuraxis, together with those developing in the pineal gland [9], sellar and suprasellar regions [10], third ventricle [11] or fourth ventricle [12].…”

Section: Discussionmentioning

confidence: 99%

Mature Teratoma of the Filum Terminale in the Elderly, Incidentally Diagnosed after an Unmyelinated Lumbar Spine Trauma

Dumitrescu

Eva²,

Munteanu³

et al. 2014

Arch Clin Cases

View full text Add to dashboard Cite

Introduction: Spinal teratoma is an extremely rare entity as it represents 0.10-0.60% of all spinal tumors. It is mainly diagnosed during the first two decades of life and can be associated with spinal dysraphism. Aim: To present a case of an asymptomatic mature teratoma of filum terminale, incidentally diagnosed in an elderly patient admitted to the Neurosurgery Department for multiple traumas after falling from 3 meters height. Case description: A 76 year-old patient was admitted in the 2 nd Neurosurgery Department, "Prof. Dr.N. Oblu" Emergency Clinical Hospital, Iaşi with multiple traumas after falling from 3 meters height. The patient presented bilateral paresthesia of lower limbs and urinary incontinence. Radiography of the dorsal-lumbar spine column in emergency highlighted a dorsal -lumbar fracture (D12-L1) with medullar compression. MRI examination revealed a neoformation of filum terminale that filled almost the entire spinal canal, which had a composite, fatty and fluid structure, corresponding to L2-L4 and compressing the medullary cone. The neurosurgical decision was the excision of the entire neoformation. The histopathological examination of excised pieces revealed the presence of adipose tissue mixed together with striated and smooth muscle fibers, small and large cysts lined by various epithelia ranging from malpighian keratinized multilayered to simple ciliated columnar epithelium. No immature or malignant cells were identified and therefore the diagnosis was mature teratoma of filum terminale. The evolution of the patient was favorable with the remission of the neurological deficit. Conclusions: Our patient is one of the oldest patients diagnosed up to date with a mature teratoma of filum terminale. Moreover, the location of neoformation at the lumbar (L2-L4) level is extremely rare. This case also highlights the fact that this mature teratoma was discovered by chance, when the patient came to the Neurosurgery Department for a spinal injury due to a falling from a tree.

show abstract

“…16,42 Epidemiology: The majority of these tumors, that is almost 90%, are found during the 1st year of life. They are rarely diagnosed later.…”

Section: Teratomamentioning

confidence: 99%

Pathologic aspects of skull base tumors

Marszałek

Szylberg

Wiśniewski

2016

Reports of Practical Oncology & Radiotherapy

View full text Add to dashboard Cite

Skull base tumors form a highly heterogeneous group. As there are several structures in this anatomical site, a large number of different primary malignancies might develop, as well as a variety of secondary (metastatic) tumors. In this article, the most common malignancies are presented, along with a short histopathologic description. For some entities, an immunohistochemical profile is also given that should be helpful in proper diagnosis. As many pathologic diagnoses nowadays also include genetic studies, the most common genetic abnormalities in skull base tumors are presented.

show abstract

Suprasellar Mature Cystic Teratoma: An Unusual Location for an Uncommon Tumor

Cited by 12 publications

References 16 publications

Endoscopic Resection of Skull Base Teratoma in Klippel-Feil Syndrome through Use of Combined Ultrasonic and Bipolar Diathermy Platforms

Endoscopic Resection of Skull Base Teratoma in Klippel-Feil Syndrome through Use of Combined Ultrasonic and Bipolar Diathermy Platforms

Mature Teratoma of the Filum Terminale in the Elderly, Incidentally Diagnosed after an Unmyelinated Lumbar Spine Trauma

Pathologic aspects of skull base tumors

Contact Info

Product

Resources

About