Suppurative meningitis due to streptococci of lancefield group B: A study of 33 infants

Baker, Carol J.; Barrett, Fred F.; Gordon, Ralph C.; Yow, Martha D.

doi:10.1016/s0022-3476(73)80606-7

Cited by 281 publications

(121 citation statements)

References 11 publications

Supporting

Mentioning

111

Contrasting

Unclassified

Order By: Relevance

“…[1][2][3] From the 1960s through the 1990s, Streptococcus agalactiae, group B streptococcus (GBS), overtook S. aureus as the primary Gram-positive infecting organism. [4][5][6][7] Over the course of the following years, the list of not uncommon pathogens has continued to grow and be influenced by current medical practices and the pressures applied on these microorganisms from the rampant use of antimicrobials, including many broad-spectrum drugs that have contributed to the selection for multidrug-resistant organisms in and out of the hospital settings. CONS are now the most prevalent infecting organism in the neonatal setting, owing this distinction to the late-onset infection rate in neonatal intensive care units.…”

Section: Historical Perspectivesmentioning

confidence: 99%

See 1 more Smart Citation

The changing spectrum of neonatal infectious disease

Plano

2010

J Perinatol

View full text Add to dashboard Cite

To understand the changing spectrum of neonatal infectious disease, one must first be familiar with the history, the variety of organisms and the progression of change of neonatal infections over the years. As progressively more immature neonates are surviving, the spectrum of infectious disease has changed in response to current medical practice responsible for this success and to selective pressures on the microorganisms. The surviving very low birth weight infants are at a significant risk for contracting infections from this expanding repertoire of pathogens. Microorganisms once thought seemingly benign and nonpathogenic are now commonly accepted as pathogens and are among the most likely organisms to cause infections in this extremely vulnerable patient population. When considering the possible identity of infecting organisms and attempting to tailor specific therapies to decrease unwanted consequences, one must consider the level of maturity and the age of neonate, as well as the intensity of care necessary for a successful outcome. This brief review focuses primarily on the changing spectrum of bacterial and fungal infections and will not substantially address viral infections.

show abstract

Section: Historical Perspectivesmentioning

confidence: 99%

“…[8][9][10] Joining these organisms are E. coli, and multidrug-resistant Gram-negative organisms including Pseudomonas, Klebsiella and the fungi. [3][4][5][6][7][8][9][10][11][12] Although systemic infection of the term newborn indeed occurs, severe sepsis is now primarily a complication of preterm delivery.…”

Section: Historical Perspectivesmentioning

confidence: 99%

The changing spectrum of neonatal infectious disease

Plano

2010

J Perinatol

View full text Add to dashboard Cite

show abstract

“…[1][2][3][4] Multiple clinical trials demonstrated that the administration of intrapartum antibiotic prophylaxis (IAP) to mothers colonized with GBS was an effective means of preventing GBS infection that occurred before 7 days of age, that is, early onset (EOGBS) disease. 5 As a result, the Centers for Disease Control and Prevention (CDC) published guidelines recommending risk-based screening and prophylaxis of GBS carriers in 1996.…”

Section: Introductionmentioning

confidence: 99%

Continued early onset group B streptococcal infections in the era of intrapartum prophylaxis

et al. 2008

View full text Add to dashboard Cite

Objective: The objective of the study was to determine the rate of early onset group B streptococcus (EOGBS) infection in Utah and identify potential areas of failure in EOGBS prevention.Study Design: We queried the microbiology records of Intermountain Healthcare for infants with culture-confirmed EOGBS between 1 January 2002 and 31 May 2006 and calculated rates of EOGBS per 1000 deliveries. We reviewed the infant and maternal records of each EOGBS case to identify possible failures in EOGBS prevention.Result: There were 54 cases of EOGBS among the 127 205 births (0.42/1000 births). Of all, 12 were preterm. Of the 39 (93%) women prenatally screened for GBS, 31 (79%) had negative results and 7/8 (88%) women with positive prenatal GBS screens either did not receive intrapartum antibiotic prophylaxis (IAP) or received inadequate IAP. Of the 54 infants with EOGBS, 3 (6%) died.Conclusion: Utah's rates of EOGBS were higher than the national average. Factors associated with EOGBS include missed screening opportunities, inadequate IAP, and false-negative maternal GBS culture.

show abstract

“…O Streptococcus agalactiae (SGB) foi reconhecido como causa importante de morbidade e mortalidade neonatal nos Estados Unidos no início de 1970 (1)(2)(3)(4) , com taxa de mortalidade de 15 a 50%.…”

Section: Introductionunclassified

“…A prevalência de colonização no trato genital em mulheres grávidas varia de 10 a 30% (5,6) e a transmissão vertical ocorre em 30 a 70% de neonatos cujas mães são colonizadas pelo SGB na gestação (1) . Recomendações de profilaxia intraparto para prevenir doença perinatal pelo SGB de início precoce foram revisadas recentemente pelo Centers for Disease Control and Prevention (CDC) (7) .…”

Section: Introductionunclassified

Gestantes colonizadas pelo Streptococcus do grupo B e seus recém-nascidos: análise crítica da conduta adotada no Instituto Fernandes Figueira, Fundação Oswaldo Cruz

Costa

Carvalho

Pone

et al. 2010

Rev. paul. pediatr.

View full text Add to dashboard Cite

Conclusões: Apesar de o protocolo para prevenção de sepse precoce pelo SGB estar implementado na instituição, ainda é possível observar falhas na profilaxia intraparto materna. Essas falhas representam oportunidades perdidas na prevenção da sepse precoce pelo SGB.Palavras-chave: streptococcus agalactiae; antibioticoprofilaxia; sepse; fidelidade a diretrizes. ABSTRACTObjective: To evaluate the use of the guidelines of the Centers of Disease Control (CDC, 2002) regarding the prophylaxes of group B Streptococcus (GBS) early onset neonatal sepsis.Methods: We conducted a retrospective study by chart review of 125 pregnant women colonized by GBS and 133 neonates born at a 3 rd level maternity hospital, from January/2003 to December/2006. The intrapartum management was deemed correct when pregnant women were given prophylactic antibiotic at least four hours before delivery or when they did not receive medication but were submitted to elective cesarean section.

show abstract

Suppurative meningitis due to streptococci of lancefield group B: A study of 33 infants

Cited by 281 publications

References 11 publications

The changing spectrum of neonatal infectious disease

The changing spectrum of neonatal infectious disease

Continued early onset group B streptococcal infections in the era of intrapartum prophylaxis

Gestantes colonizadas pelo Streptococcus do grupo B e seus recém-nascidos: análise crítica da conduta adotada no Instituto Fernandes Figueira, Fundação Oswaldo Cruz

Contact Info

Product

Resources

About