Background:
Salvia chloroleuca Rech. f. & Allen is an endemic or native perennial medicinal plant that grows wild in the central, north, and northeast of Iran
Objective:
The aim of this research was to give an overview of the chemical profile of Salvia chloroleuca, the principal chemical compounds, and their various biological activities and uses in traditional pharmacopoeia.
Method:
The literature search was done via specialized search databases (Scifinder, Scopus, PubMed, Web of Science and Google Scholar).
Results:
From the past to the present, people have consumed Salvia chloroleuca for carminatives, antibacterial, antitumoural, antiviral, antifungal, antiparasitic, antirheumatics, tonics, hepatoprotective, nephroprotective, immunoprotective, anticancer and neuroprotective properties. The principal ingredients of Salvia chloroleuca are salvigenin, luteolin, cirsiliol, daucosterol, and β-sitosterol and perhaps the remedial properties of this herb are regarded to these compounds. The bioactive components extracted from Salvia chloroleuca have promising prospects and make it possible to propose diverse solutions, due to their excellent dissimilarity and bioactivity for such various usages.
Conclutions:
This research is a beneficial compilation for further investigation and betterment of diverse properties of Salvia chloroleuca secondary metabolites. This study is a valuable source of information about an important native medicinal plant. It can be more extended for new investigations in the fields of phytochemistry and pharmacology, with the purpose of searching for novel natural bioactive structures with therapeutic properties.