Suppression of Murine Preadipocyte Differentiation and Reduction of Visceral Fat Accumulation by aPetasites japonicusEthanol Extract in Mice Fed a High-Fat Diet

Anti-obesity potential of Clerodendron glandulosum.Coleb leaf aqueous extract

“…In the past few decades, the role of PPAR␥-2 and SERBP1c in regulation of obesity and adipocyte differentiation (Chien et al, 2005;Brown and Goldstein, 1997;Kim et al, 2008b;Oben et al, 2008) has been highlighted and hence, PPAR␥-2 agonists and antagonists of synthetic or herbal origin have gained wide commercial popularity as therapeutic agents (Nerurkar et al, 2010;Watanabe et al, 2010). Significant up regulation of PPAR␥-2 and SERBP1c mRNA expressions in the present study are in accordance with the previous reports (Lee et al, 2008;Watanabe et al, 2010).…”

Anti-Obesity Effects of Germinated Brown Rice Extract through Down-Regulation of Lipogenic Genes in High Fat Diet-Induced Obese Mice

“…C/EBP-, PPAR-, and SREBP-1c are transcription factors important in adipogenesis. [38][39][40] C/EBP-and PPAR-, mainly found in adipose tissue, are key adipogenesis and lipogenesis transcription factors. 38,41) In the present study, GBR administration significantly suppressed the expression of these transcription factors in adipose tissue.…”

Anti-obesity effects of Geranium thunbergii extract via improvement of lipid metabolism in high-fat diet-induced obese mice

“…Obesity is characterized by increased fat mass due to an increase in the size and number of adipocytes that differentiated from preadipocytes (19). In obese conditions, adipocytes accumulate large amounts of lipids and become enlarged.…”