Suppression of Helicobacter pylori infection during intensive care stay: Related to stress ulcer bleeding incidence?

Diagnostics of Helicobacter pylori Infection in Patients with Peptic Ulcer Bleeding

“…Potential reasons relate to all factors reducing H. pylori colonization density: lower acid output, older age, and severe illness. During intensive care, suppression of Helicobacter pylori infection has been reported which was not related to drugs [31]. The concept of a recent decline of H. pylori colonization density, occurring already before the onset of bleeding, is further supported by the following two of our observations: Firstly, four patients without HpSuT had active gastritis in the absence of identifiable H. pylori colonization.…”

Systematic reviews of the clinical effectiveness and cost-effectiveness of proton pump inhibitors in acute upper gastrointestinal bleeding

“…Re-bleeding not evaluated Sheu, No control group (all patients received H. pylori eradication therapy) Less than 6 months' follow-up Siu, 1999 194 No control group (all patients received H. pylori eradication therapy) Sonnenberg, 1999 195 No previous UGI bleeding van der Voort, 2001 196…”

An observational study of upper gastrointestinal bleeding in intensive care units: Is Helicobacter pylori the culprit?*

“…Indeed, stool antigen detection was positive for two patients with UGIB for whom gastric biopsy was negative. In ICU patients, selective digestive decontamination has been shown to reduce the prevalence of active H. pylori infection from 38% to 0% in Ͻ10 days (32). Contrary to histology, stool antigen detection focuses on bacterial wall antigens and therefore does not require intact cells.…”