Superoxide-scavenging and Tyrosinase-inhibitory Activities of the Extracts of Some Chinese Medicines

Effect of Oren-gedoku-to (Huanglian-Jie-Du-Tang) extract on disruption of hepatic antioxidant defense systems in rats treated with d-galactosamine

“…Miao et al (1997) have shown that when Coptidis rhizoma, Scutellariae radix, and Phellodendri cortex are extracted with 50% methanol, the Scutellariae radix extract has much higher O 2 − -scavenging activity than the Phellodendri cortex extract, while the Coptidis rhizoma extract has little O 2 − -scavenging activity. Yokozawa et al (1997) have reported that although the boiled water extract of Coptidis rhizoma, Gardeniae frucuts, Scutellariae radix or Phellodendri cortex inhibits lipid peroxidation induced by H 2 O 2 in rat liver homogenates, the Coptidis rhizoma extract has the highest inhibitory activity, followed in the order of strength by the Gardeniae frucut extract > the Scutellariae radix extract > the Phellodendri cortex extract.…”

Hepatoprotective effects of Coptidis rhizoma aqueous extract on carbon tetrachloride-induced acute liver hepatotoxicity in rats

“…Rhizoma of Coptis chinensis Franch., one of the species, was chosen for our study due to its plentiful cultivation in China and most popular in TCM practice. Miao et al (1997) have shown that when Coptidis rhizoma, Scutellariae radix, and Phellodendri cortex are extracted with 50% methanol, the Scutellariae radix extract has much higher O 2 − -scavenging activity than the Phellodendri cortex extract, while the Coptidis rhizoma extract has little O 2 − -scavenging activity. Yokozawa et al (1997) have reported that although the boiled water extract of Coptidis rhizoma, Gardeniae frucuts, Scutellariae radix or Phellodendri cortex inhibits lipid peroxidation induced by H 2 O 2 in rat liver homogenates, the Coptidis rhizoma extract has the highest inhibitory activity, followed in the order of strength by the Gardeniae frucut extract > the Scutellariae radix extract > the Phellodendri cortex extract.…”

Pharmacological Evaluation of Bangladeshi Medicinal Plants for Antioxidant Activity

“…Similar plants used in traditional Chinese medicines have also shown superoxide scavenging active components (Okuda et al, 1995;Miao et al, 1997). Potent superoxide scavenging activity was found from ginger (Zingiber officinale Roscoe), and the active antioxidant compound isolated was gingerol; its structure was confirmed as 3-decanone, 5-hydroxy-1 (4-hydroxy-3-methoxy phenyl)-3-one on the basis of spectral evidence (Khanom et al, 2003).…”