“…3 Signs and symptoms include swelling of the face, head, neck, breast, cough, dyspnea, distended neck veins, orthopnea, and conjunctival suffusion; collateral circulation leads to distension of superficial veins in the chest wall. 3 Other less common symptoms of SVC syndrome include stridor, hoarseness, dysphagia, pleural effusion, head plethora, headache, nausea, lightheadedness, syncope, change in vision, altered mental status, upper body edema, cyanosis, papilledema, stupor, and coma. 1 Some rare but serious clinical consequences reported in SVC syndrome include cerebral edema and upper respiratory compromise secondary to edema of larynx and pharynx.…”