Superior Sagittal Sinus Thrombosis

Gettelfinger, Dennis M.; Kokmen, Emre

doi:10.1001/archneur.1977.00500130022004

Cited by 152 publications

(54 citation statements)

References 31 publications

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“…17 The only therapeutic conclusion that can be drawn from the present study is that anticoagulants were not harmful since among the 23 heparin treated patients, there was not a single death and 19 made a complete recovery. Furthermore, the dramatic improvement seen in 3 patients just after initiation of heparin does suggest that anticoagulants may be beneficial; 9 -l0 ' 28 this seemed to be the case even in the patient who had a CT scan suggestive of an hemorrhagic infarct.…”

mentioning

confidence: 62%

Cerebral venous thrombosis--a review of 38 cases.

Bousser¹,

Chiras²,

Bories³

et al. 1985

Stroke

683

420

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199SUMMARY A series of 38 patients with angiographically proven cerebral venous thrombosis (CVT) affecting dural sinuses is reported. This study shows that CVT is not rare, that the clinical diagnosis is extremely difficult because of the variable modes of onset and groupings of symptoms, that most CT findings are non specific and that angiography remains the best diagnostic tool. Only 4 patients died, which suggests a more benign outcome than classically described. None of the 23 heparin treated patients died, which indicates that anticoagulants were not harmful in this series.

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mentioning

confidence: 62%

Cerebral venous thrombosis--a review of 38 cases.

Bousser¹,

Chiras²,

Bories³

et al. 1985

Stroke

683

420

View full text Add to dashboard Cite

show abstract

“…Several other studies followed, but the results were inconsistent. 24,33 Therefore, Scott et al 59 sought to improve the safety profile through local infusion. A 33-year-old man presented with progressive headache, but his condition quickly deteriorated to a comatose state.…”

Section: Fibrinolytic Agentsmentioning

confidence: 99%

A review of therapeutic strategies for the management of cerebral venous sinus thrombosis

Medel¹,

Monteith²,

Crowley³

et al. 2009

FOC

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Object Although initially described in the 19th century, cerebral venous sinus thrombosis (CVST) remains a diagnostic and therapeutic dilemma. It has an unpredictable course, and the propensity for hemorrhagic infarction produces significant consternation among clinicians when considering anticoagulation. It is the purpose of this review to analyze the evidence available on the management of CVST and to provide appropriate recommendations. Methods A thorough literature search was conducted through MEDLINE and PubMed, with additional sources identified through cross-referencing. A classification and level of evidence assignment is provided for recommendations based on the American Heart Association methodologies for guideline composition. Results Of the publications identified, the majority were isolated case reports or small case series. Few prospective trials have been conducted. Existing data support the use of systemic anticoagulation as an initial therapy in all patients even in the presence of intracranial hemorrhage. Chemical and/or mechanical thrombectomy, in conjunction with systemic anticoagulation, is an alternative strategy in patients with progressive deterioration on heparin therapy or in those who are moribund on presentation. Mechanical thrombectomy is probably preferred in patients with preexisting intracranial hemorrhage. Conclusions Effective treatments exist for the management of CVST, and overall outcomes are more favorable than those for arterial stroke. Further research is necessary to determine the role of individual therapies; however, the rarity of the condition poses a significant limitation.

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“…He believed this therapy arrested progression of the illness and recommended it. More recently, Gettelfinger and Kohmen 11 reported that medical therapy with antiedema agents and dipyridamole may be the treatment of choice. Seventeen patients in our series received conservative treatment with anticonvulsants, antiedema agents and dipyridamole.…”

mentioning

confidence: 99%

Intracranial venous thrombosis in young women.

Estañol¹,

Rodriguez²,

Conte³

et al. 1979

Stroke

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SUMMARY Twenty women of child-bearing age with intracraniai venous thrombosis are reported. Thirteen developed thrombosis post-partum; 6 while on oral contraceptives. In one patient no cause was found. All diagnoses were confirmed by carotid angiography and in 10 out of 14 patients laboratory data indicated a hypercoagulable state. Coagulation studies were performed in 14 normal puerperal women, matched by age, who served as controls. No statistical differences was found between thrombotic and control groups. Radiologic signs of sino-venous occlusion are reviewed. Conservative treatment with anti-edematous agents, anticonvulsants and antiplatelet aggregants is advocated.

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Superior Sagittal Sinus Thrombosis

Abstract: Seven patients had superior sagittal sinus thrombosis diagnosed by cerebral arteriography. We recommend that anticoagulants not be used in the therapy of this entity, but rather that one should rely on antiedematous agents and anticonvulsants.

Cited by 152 publications

References 31 publications

Cerebral venous thrombosis--a review of 38 cases.

Cerebral venous thrombosis--a review of 38 cases.

A review of therapeutic strategies for the management of cerebral venous sinus thrombosis

Intracranial venous thrombosis in young women.

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