Intracranial venous thrombosis in young women.

Estañol, B; Rodriguez, Alej O; Conte, Guillermo; Aleman, Jose; Loyo, Maur O; Pizzuto, J

doi:10.1161/01.str.10.6.680

Cited by 90 publications

(31 citation statements)

References 21 publications

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“…She completely recovered after treatment with heparin, hydrochlorothiazide, and ampicillin. Estanol et al 32 reported 20 women between the ages of 15 and 45 years with intracranial venous thrombosis; 14 of the 20 studied were without evidence of circulating anticoagulant.…”

Section: Discussionmentioning

confidence: 99%

Cerebral venous thrombosis with lupus anticoagulants. Report of two cases.

Levine¹,

Kieran²,

Puzio³

et al. 1987

Stroke

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Section: Discussionmentioning

confidence: 99%

Cerebral venous thrombosis with lupus anticoagulants. Report of two cases.

Levine¹,

Kieran²,

Puzio³

et al. 1987

Stroke

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“…Rheumatologic diseases that have been associated with thrombosis include systemic lupus erythematosus and Behcet's disease. Other conditions that have been associated with both hypercoagulability and cerebral dural thrombosis include nephrotic syndrome, anti-thrombin III deficiency, cancer, pregnancy (ie, postpartum period), 4 and oral contraceptive use. [5][6][7][8] Protein S is a cofactor for anticoagulant and fibrinolytic properties of activated protein C. Reduced protein S levels can be seen in nephrotic syndrome, pregnancy, and the use of oral contraceptives.…”

Section: Commentsmentioning

confidence: 99%

Transverse Sinus Thrombosis: An Unusual Cause of Headache

Wasson¹,

Redenbaugh²

1997

Headache

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A 24-year-old woman presented with headache of 6 days' duration, described as throbbing pain in the right periorbital region radiating to her right ear and neck. The pain was unresponsive to oral analgesics. She had no speech or hearing difficulties, no previous history of migraines, and no family history of neurologic disease. Her medications included oral contraceptives for 8 months' duration. This report describes the salient features of dural sinus thrombosis and recent advances in diagnostic and therapeutic procedures. The relationship between oral contraceptives and protein S levels is also discussed. Cerebral dural sinus thrombosis should be considered in the differential of new onset of headaches, seizures, or focal neurological deficits.

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“…The scarce studies that do exist are mostly retrospective or comprise a small number of patients. 5,15,16 The International Study on Cerebral Venous and dural sinus Thrombosis (ISCVT) is, to date, the largest prospective cohort study on CVST. 3 Women comprise approximately three fourths of patients included in this cohort.…”

mentioning

confidence: 99%

Cerebral Venous and Sinus Thrombosis in Women

Coutinho

Ferro

Canhão

et al. 2009

Stroke

346

268

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Background and Purpose-Little is known about the gender-specific manifestations of cerebral venous and sinus thrombosis, a disease that is much more common in women than men. Methods-We used data of the International Study on Cerebral Vein and Dural sinus Thrombosis (ISCVT), a multicenterprospective observational study, to analyze gender-specific differences in clinical presentation, etiology, and outcome of cerebral venous thrombosis. Results-Four hundred sixty-five of a total of 624 patients were women (75%). Women were significantly younger, had less often a chronic onset of symptoms, and had more often headache at presentation. There were no gender differences in ancillary investigations or treatment. A gender-specific risk factor (oral contraceptives, pregnancy, puerperium, and hormonal replacement therapy) was present in 65% of women. Women had a better prognosis than men (complete recovery 81% versus 71%l Pϭ0.01), which was entirely due to a better outcome in female patients with gender-specific risk factors. Women without gender-specific risk factors are similar to men in clinical presentation, risk factor profile, and outcome. Logistic regression analysis confirmed that the absence of gender-specific risk factors is a strong and independent predictor of poor outcome in women with sinus thrombosis (OR, 3.7; CI, 1.9 to 7.4). Conclusions-Our study identified important differences between women and men in presentation, course, and risk factors of cerebral venous and sinus thrombosis and showed that women with a gender-specific risk factor have a much better prognosis than other patients.

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Intracranial venous thrombosis in young women.

Cited by 90 publications

References 21 publications

Cerebral venous thrombosis with lupus anticoagulants. Report of two cases.

Cerebral venous thrombosis with lupus anticoagulants. Report of two cases.

Transverse Sinus Thrombosis: An Unusual Cause of Headache

Cerebral Venous and Sinus Thrombosis in Women

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