Superior performance of a graphdiyne self-powered biosensor with exonuclease III-assisted signal amplification for sensitive detection of microRNAs

Abstract

Graphdiyne (GDY) is an sp and sp2 co-hydrocarbon allotrope whose particular structure endows it with many fascinating properties, including abundant chemical bonds, high conjugation, natural pores, high carrier mobility, high...

Current Advances in the Synthesis, Properties, and Biomedical Applications of Two-Dimensional Graphdiyne: A Review

“…2D carbon nanomaterials typically have high specific surface area and excellent physicochemical properties for energy storage, catalysis, solar cells, optoelectronic devices, and biomedical and environmental applications. − In 2010, GDY was successfully synthesized on copper (Cu) foil by a cross-coupling reaction for the first time, representing the theoretical idea of GDY for decades has become a reality and officially announcing a fresh addition to the 2D carbon nanomaterial family . Although the synthesis conditions of GDY were relatively harsh before, with the development, new processes for preparing GDY emerged, such as chemical vapor deposition (CVD), vapor–liquid–solid (VLS), explosion method, and so on, which laid a foundation for their subsequent large-scale preparation and industrial production. , …”

“…32 Although the synthesis conditions of GDY were relatively harsh before, with the development, new processes for preparing GDY emerged, such as chemical vapor deposition (CVD), vapor−liquid−solid (VLS), explosion method, and so on, which laid a foundation for their subsequent large-scale preparation and industrial production. 33,34 Unlike conventional carbon nanomaterials with a single sp 2 hybridization, the 2D planar structure of GDY consists of a benzene ring (sp 2 -hybridized carbon) and an acetylene bond (sp-hybridized carbon) together. 35 The structure gives this synthetic carbon stability qualities by inheriting the benefits of carbene and graphene.…”