Current Advances in the Synthesis, Properties, and Biomedical Applications of Two-Dimensional Graphdiyne: A Review

Abstract

Graphdiyne (GDY), a new kind of two-dimensional carbon nanomaterial, has abundant chemical bonds, a highly πconjugated structure, uniformly distributed pores, a large surface area, and good biocompatibility and has been applied in drug delivery, biosensing, antibacterial processes, and cancer therapy. Herein, this review is intended to provide an introduction of current advances in bioapplications of GDY, which covers the synthetic methods, structure and properties of GDY, and its application in antimicrobial processes, cancer therapy, biosensing, and bioimaging. Finally, we provide a perspective on future development in research relevant to GDY. We believe that this review can provide meaningful assistance for breakthroughs and innovations in the field of GDY.

Steering sp‐Carbon Content in Graphdiynes for Enhanced Two‐Electron Oxygen Reduction to Hydrogen Peroxide

“…[1][2][3][4][5] However, pristine sp 2 -hybridized carbon materials often exhibit poor 2eORR activity due to the exceptionally high chemical stability of the sp 2 -carbon atoms. [6][7][8][9][10] Graphdiynes (GDY), new carbon allotropes composed of sp and sp 2 -hybridized carbon atoms, [11][12][13][14][15] have garnered significant attention in various fields, including energy storage and conversion, cancer therapy, biosensing, catalysis, etc., [16][17][18][19][20][21][22][23][24][25] benefiting from their adjustable physicochemical properties as a result of the diverse structural patterns of the acetylene linkage and aromatic ring and unique pore structures. [26][27][28][29] Compared with graphene, which is composed only of sp 2 -hybridized carbon, GDYs have a stronger catalytic reactivity because of their high-energy acetylenic linkages with electron-rich ( orbitals).…”

Steering sp‐Carbon Content in Graphdiynes for Enhanced Two‐Electron Oxygen Reduction to Hydrogen Peroxide

“…[1][2][3][4][5] However, pristine sp 2 -hybridized carbon materials often exhibit poor 2eORR activity due to the exceptionally high chemical stability of the sp 2 -carbon atoms. [6][7][8][9][10] Graphdiynes (GDY), new carbon allotropes composed of sp and sp 2 -hybridized carbon atoms, [11][12][13][14][15] have garnered significant attention in various fields, including energy storage and conversion, cancer therapy, biosensing, catalysis, etc., [16][17][18][19][20][21][22][23][24][25] benefiting from their adjustable physicochemical properties as a result of the diverse structural patterns of the acetylene linkage and aromatic ring and unique pore structures. [26][27][28][29] Compared with graphene, which is composed only of sp 2 -hybridized carbon, GDYs have a stronger catalytic reactivity because of their high-energy acetylenic linkages with electron-rich ( orbitals).…”