Superhydrophobicity‐mediated enhanced enzymatic kinetics and high‐performance bioassays

Abstract

As a typical superwettability behavior, superhydrophobicity can provide an appropriate strategy to enhance the mass transport in multiphase chemical reactions. In the oxidase-based enzymatic reactions, the elaborately regulating of reactant oxygen are critical to the development of an oxidase-based highperformance biosensor. In solid-liquid diphase condition, however, the kinetics of oxidase-catalyzed reactions is inhibited by delayed mass transport and poor solubility of oxygen. To address this limitation, the design of the solid-liquid-air triphase interface is proposed according to the binary cooperation of superhydrophobicity and hydrophilicity. On the triphase joint interface, oxygen required for the oxidase-catalyzed reactions can diffuse directly to the reaction center from the air phase through the micro/nanostructured superhydrophobic substrate, thus improving the kinetics of the oxidase-catalyzed reactions. In this minireview, we summarize recent advances in the fabrication of triphase reaction system based on different superhydrophobic substrate for oxidase-based biosensors. Common substrates including fibrous network, nanowire arrays, 3D porous framework, and hollow sphere structures are outlined in categories.

Impact of the Undersaturation Level on the Longevity of Superhydrophobic Surfaces in Stationary Liquids

“…Superhydrophobic surface (SHS) is an emerging material with many applications such as drag reduction, , anticorrosion, , antibiofouling, − anti-icing, − energy harvesting, , and biosensing. , Most of these applications rely on the presence of micro/nanoscale gas bubbles trapped within the surface texture when the SHS contacts with liquid. However, the beneficial gas trapped on a SHS can slowly dissolve in the ambient liquid, shortening the longevity of SHS .…”

Plasmonic Imaging of Spatiotemporal Electrochemical Bubble Evolution on Smooth Electrodes with Different Wettabilities

“…[1][2][3][4][5] Among them, bubble engineering has also been demonstrated to play a vital role in practical scenarios. [6,7,8] For instance, the construction of superaerophobic electrodes for gas evolution reactions [9] and superaerophilic electrodes for gas consumption reactions, [10] can effectively tailor the disengagement and adhesion of bubbles on electrodes, improving performance significantly.…”

Material assembly by droplet drying: From mechanics theories to applications

“…It is important to mention that the droplets discussed in this review exclusively pertain to nonreactive systems. When reactive components are introduced, such as chemically reactive particles or reactive solvents, the drying process can result in unintended chemical reactions, alterations in particle properties, or modifications to the assembly dynamics, [39][40][41] which is beyond the scope of this review.…”