Superhydrophobic cotton gauze with durably antibacterial activity as skin wound dressing

Liu, Gongyan; Xiang, Jun; Xia, Qiongfen; Li, Kaijun; Lan, Tianxiang; Yu, Ling

doi:10.1007/s10570-018-2110-y

Cited by 50 publications

(20 citation statements)

References 40 publications

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“…Bacterial infection will disrupt these phases, and the delayed wound healing will result in chronic infection at the wound site, causing the infection to worsen [ 6 ]. Traditional dressings, such as various gauze and bandage, are commonly used materials in the wound treatment because of their low cost, wide source of raw materials, soft texture, and strong absorption capacity readily preventing the accumulation of wound seepage [ 7 – 9 ]. Unfortunately, these traditional dressings have many drawbacks, such as limited ability to promote wound healing and poor moisturizing effect, resulting in adhesion and scab of dressing in the wound site.…”

Section: Introductionmentioning

confidence: 99%

A cellulose nanofibril-reinforced hydrogel with robust mechanical, self-healing, pH-responsive and antibacterial characteristics for wound dressing applications

et al. 2022

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Background Bacterial infection in wounds has become a major threat to human life and health. With the growth use of synthetic antibiotics and the elevated evolution of drug resistant bacteria in human body cells requires the development of novel wound curing strategies. Herein, a novel pH-responsive hydrogel (RPC/PB) was fabricated using poly(vinyl alcohol)-borax (PB) and natural antibiotic resveratrol grafted cellulose nanofibrils (RPC) for bacterial-infected wound management. Results In this hydrogel matrix, RPC conjugate was interpenetrated in the PB network to form a semi-interpenetrating network that exhibited robust mechanical properties (fracture strength of 149.6 kPa), high self-healing efficiency (> 90%), and excellent adhesion performance (tissue shear stress of 54.2 kPa). Interestingly, the induced RPC/PB hydrogel showed pH-responsive drug release behavior, the cumulative release amount of resveratrol in pH 5.4 was 2.33 times than that of pH 7.4, which was adapted well to the acidic wound microenvironment. Additionally, this RPC/PB hydrogel exhibited excellent biocompatibility and antioxidant effect. Moreover, in vitro and in vivo results revealed that such RPC/PB hydrogel had excellent antibacterial, skin tissue regeneration and wound closure capabilities. Conclusion Therefore, the generated RPC/PB hydrogel could be an excellent wound dressing for bacteria-infected wound healing.

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Section: Introductionmentioning

confidence: 99%

A cellulose nanofibril-reinforced hydrogel with robust mechanical, self-healing, pH-responsive and antibacterial characteristics for wound dressing applications

et al. 2022

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“…coli and S . aureus was recorded over time via UV–vis spectrophotometer 33 . Apparently, the number of bacteria increased rapidly in the control group after 12 h incubation and gradually reached the state of saturation, while the bacterial growth was inhibited visibly due to the biocidal action of PHMB in sample group.…”

Section: Resultsmentioning

confidence: 99%

Polyhexamethylene biguanide hydrochloride anchored polymeric elastic fibers with robust antibacterial performance

Gong

Zhang²,

Luo

et al. 2021

J of Applied Polymer Sci

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Elastic fibers have been widely applied for the fabrication of biomedical textiles, artificial extracellular matrix, and functional garments, as where antibacterial property is one of the indispensable features. Herein, we developed a fresh type of non‐leaching antibacterial fiber that could effectively inactivate bacteria with durable performance to circumvent above concerns. In detail, we firstly synthesized a precursor polymer (PS‐GMA) based on styrene and glycidyl methacrylate (GMA) through free radical polymerization, then blended PS‐GMA with thermoplastic polyurethane (TPU) and processed the blend into fiber through wet spinning technology. Finally, the obtained fiber was covalently modified by polyhexamethylene biguanide hydrochloride (PHMB). The experimental results showed that the resultant fiber (named as PGPs) exhibited a strong bactericidal ability to both Staphylococcus aureus and Escherichia coli, as well as maintained excellent antibacterial properties even after ultraviolet irradiation for 7 days or 50 washing cycles. Furthermore, we explored the sterilization mechanism with respect to the bacterial morphologies and the activity of the respiratory chain dehydrogenase. In addition, the biocidal efficacy of the prepared fiber could remain approximately 100% after eight consecutive antibacterial cycles. Collectively, this work exhibited an attempt in exploitation of the intrinsically antibacterial fiber with long‐run function duration by an economical tactic.

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“…The coated fabric exhibited antibacterial activity against both E. Coli and S. Aureus, which was mainly attributed to the synergistic effect of contact-killing by the chitosan together with continuous release of Ag þ . In addition, it was found that the outer PFDT deposition could act as a barrier to prevent leaching of the silver nanoparticles during laundry, enhancing the durability of the antibacterial activity [393].…”

Section: Passive Wound Dressingsmentioning

confidence: 99%

Medical textiles

Morris

Murray

2020

Textile Progress

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Superhydrophobic cotton gauze with durably antibacterial activity as skin wound dressing

Cited by 50 publications

References 40 publications

A cellulose nanofibril-reinforced hydrogel with robust mechanical, self-healing, pH-responsive and antibacterial characteristics for wound dressing applications

A cellulose nanofibril-reinforced hydrogel with robust mechanical, self-healing, pH-responsive and antibacterial characteristics for wound dressing applications

Polyhexamethylene biguanide hydrochloride anchored polymeric elastic fibers with robust antibacterial performance

Medical textiles

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