Supercritical fluid extraction of diosgenin from tubers of Dioscorea nipponica

Liu, Ben; Lockwood, G.; Gifford, Larry

doi:10.1016/0021-9673(94)01117-w

Cited by 24 publications

(10 citation statements)

References 5 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Importance of fenugreek seeds pretreatment SC-CO 2 extraction of fenugreek seeds without both steps of pretreatment (defatting and hydrolysis) showed that diosgenin was not present in the collected extract. Importance of hydrolysis was also reported in literature [15][16][17][18] and this study proved that hydrolysis was the main step for pretreatment of fenugreek seeds necessary for diosgenin isolation by SC-CO 2 extraction.…”

Section: Resultssupporting

confidence: 67%

“…Seeds contain 1-2% steroidal sapogenins, mainly diosgenin contained in the plant as steroidal saponin glycoside. Generally, the extraction methods of diosgenin from fenugreek seeds require pretreatment of the plant including defatting as the first step, followed by acid hydrolysis with aim to prepare corresponding hydro-isolate [15][16][17][18].…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Supercritical carbon dioxide extraction of Trigonella foenum-graecum L. seeds: Process optimization using response surface methodology

Bogdanović

Tadić

Stamenić

et al. 2016

The Journal of Supercritical Fluids

View full text Add to dashboard Cite

Section: Resultssupporting

confidence: 67%

Section: Introductionmentioning

confidence: 99%

Supercritical carbon dioxide extraction of Trigonella foenum-graecum L. seeds: Process optimization using response surface methodology

Bogdanović

Tadić

Stamenić

et al. 2016

The Journal of Supercritical Fluids

View full text Add to dashboard Cite

“…The mass spectrum obtained for this compound revealed that fragment ion peaks appeared at m/z 397, 282 and 139 (Figure 4), which are characteristic of C 27 steroidal sapogenins (Ghosal et al 1974;Liu et al 1995).…”

Section: Morphological and Ultrastructural Changes In Cell Suspensionmentioning

confidence: 98%

Ultrastructural changes and diosgenin content in cell suspensions of Trigonella foenum-graecum L. by ethylene treatment

2004

View full text Add to dashboard Cite

This paper studies the effect of different concentrations of ethephon (an ethylene releasing compound) on the level of the steroidal sapogenin diosgenin in cell suspensions of Trigonella foenum-graecum L. The results reveal that diosgenin synthesis and/or accumulation was stimulated by 5 ppm ethephon treatment, an increase of 126% being observed, while concentrations of 25 ppm and 50 ppm reduced the levels of this secondary compound. Changes in the isopentenyl diphosphate isomerase activity, increased cell diameter, decreased cell packing (with all the ethephon concentrations assayed), increased cytoplasmic density (5 ppm ethephon treatment) and alterations in the membrane structures (25 and 50 ppm ethephon treatments) were also observed.

show abstract

“…Thus, supercritical fluid technology has been widely evaluated for its application in solute analysis (King, 1989;Anderson et al, 1989), the extraction of essential oils (Stahl et al, 1988), and the isolation of various flavour substances from plants (Ma et al, 1991). Also, supercritical fluids have been used to extract various phytochemicals from raw materials, such as diosgenin (Liu et al, 1995), ouabain (Xie et al, 1989), and pyrrolizidine alkaloids (Bicchi et al, 1991). Among supercritical gas solvents, carbon dioxide has been utilized the most extensively for extracting phytochemical substances from natural plants as exemplified by the extraction of various coumarins from species in the Moraceae family (Vilegas et al, 1993), and of parthenolide from Tanacetum parthenium (Smith and Burford, 1992).…”

Section: Introductionmentioning

confidence: 99%

Comparison of supercritical carbon dioxide extraction with solvent extraction of nonacosan-10-ol, α-amyrin acetate, squalene and stigmasterol from medicinal plants

et al. 1997

View full text Add to dashboard Cite

Supercritical carbon dioxide extraction was carried out in the temperature range 35 to 60°C and from 10 to 30 MPa in order to obtain phytochemical components from several medicinal plants. These were nonacosan‐10‐ol (1) from the aerial parts of Ephedra sinica, α‐amyrin acetate (2) from the root bark of Morus alba, and squalene (3) and stigmasterol (4) from the entire plant of Spirodela polyrhiza. For comparison, Soxhlet extraction with n‐hexane was also carried out for these constituents. In the case of supercritical carbon dioxide extraction of 1, 2 and 4, the extraction yields tended to increase with increased temperature when the pressure was above 20 MPa. However, extraction yields were maximal at 40°C or 50°C below 15 MPa. When the amounts of extracts obtained by supercritical extraction are compared with those by Soxhlet extraction using n‐hexane, it is apparent that supercritical carbon dioxide extraction can be used as an alternative method in the case of squalene and nonacosan‐10‐ol. © 1997 John Wiley & Sons, Ltd.

show abstract

Supercritical fluid extraction of diosgenin from tubers of Dioscorea nipponica

Cited by 24 publications

References 5 publications

Supercritical carbon dioxide extraction of Trigonella foenum-graecum L. seeds: Process optimization using response surface methodology

Supercritical carbon dioxide extraction of Trigonella foenum-graecum L. seeds: Process optimization using response surface methodology

Ultrastructural changes and diosgenin content in cell suspensions of Trigonella foenum-graecum L. by ethylene treatment

Comparison of supercritical carbon dioxide extraction with solvent extraction of nonacosan-10-ol, α-amyrin acetate, squalene and stigmasterol from medicinal plants

Contact Info

Product

Resources

About